This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5m5h

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (18:26, 1 November 2023) (edit) (undo)
 
Line 3: Line 3:
<SX load='5m5h' size='340' side='right' viewer='molstar' caption='[[5m5h]], [[Resolution|resolution]] 4.50&Aring;' scene=''>
<SX load='5m5h' size='340' side='right' viewer='molstar' caption='[[5m5h]], [[Resolution|resolution]] 4.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5m5h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M5H OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5M5H FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5m5h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M5H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M5H FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yidC, ECS88_4129 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.5&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5m5h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m5h OCA], [http://pdbe.org/5m5h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m5h RCSB], [http://www.ebi.ac.uk/pdbsum/5m5h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m5h ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m5h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m5h OCA], [https://pdbe.org/5m5h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m5h RCSB], [https://www.ebi.ac.uk/pdbsum/5m5h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m5h ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/YIDC_ECO45 YIDC_ECO45]] Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
+
[https://www.uniprot.org/uniprot/YIDC_ECOLI YIDC_ECOLI] Inner membrane protein required for the insertion and/or proper folding and/or complex formation of integral inner membrane proteins. Involved in integration of membrane proteins that insert dependently and independently of the Sec translocase complex, as well as at least 2 lipoproteins. Its own insertion requires SRP and is Sec translocase-dependent. Essential for the integration of Sec-dependent subunit a of the F(0)ATP synthase, FtsQ and SecE proteins and for Sec-independent subunit c of the F(0)ATP synthase, M13 phage procoat and the N-terminus of leader peptidase Lep. Probably interacts directly with Sec-independent substrates. Sec-dependent protein FtsQ interacts first with SecY then subsequently with YidC. Sec-dependent LacY and MalF require YidC to acquire tertiary structure and stability, a chaperone-like function, but not for membrane insertion. Stable maltose transport copmplex formation (MalFGK(2)) also requires YidC. Partially complements a Streptococcus mutans yidC2 disruption mutant.<ref>PMID:10675323</ref> <ref>PMID:10949305</ref> <ref>PMID:12724529</ref> <ref>PMID:12950181</ref> <ref>PMID:15140892</ref> <ref>PMID:15067017</ref> <ref>PMID:17073462</ref> <ref>PMID:18456666</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 25: Line 25:
__TOC__
__TOC__
</SX>
</SX>
-
[[Category: Bacillus coli migula 1895]]
+
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Beckmann, R]]
+
[[Category: Beckmann R]]
-
[[Category: Berninghausen, O]]
+
[[Category: Berninghausen O]]
-
[[Category: Buschauer, R]]
+
[[Category: Buschauer R]]
-
[[Category: Crevenna, A H]]
+
[[Category: Crevenna AH]]
-
[[Category: Kedrov, A]]
+
[[Category: Kedrov A]]
-
[[Category: Lamb, D C]]
+
[[Category: Lamb DC]]
-
[[Category: Sluis, E van der]]
+
[[Category: Wickles S]]
-
[[Category: Wickles, S]]
+
[[Category: Van der Sluis E]]
-
[[Category: Membrane protein]]
+
-
[[Category: Nanodisc]]
+
-
[[Category: Protein transport]]
+
-
[[Category: Ribosome ligand]]
+

Current revision

RIBOSOME-BOUND YIDC INSERTASE

5m5h, resolution 4.50Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5m5h"
Personal tools