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6m66

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Current revision (05:46, 13 May 2020) (edit) (undo)
 
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==The Cryo-EM Structure of Human Pannexin 1==
==The Cryo-EM Structure of Human Pannexin 1==
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<StructureSection load='6m66' size='340' side='right'caption='[[6m66]]' scene=''>
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<StructureSection load='6m66' size='340' side='right'caption='[[6m66]], [[Resolution|resolution]] 4.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M66 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6M66 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6m66]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M66 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6M66 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6m66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m66 OCA], [http://pdbe.org/6m66 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6m66 RCSB], [http://www.ebi.ac.uk/pdbsum/6m66 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6m66 ProSAT]</span></td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PANX1, MRS1, UNQ2529/PRO6028 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6m66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m66 OCA], [http://pdbe.org/6m66 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6m66 RCSB], [http://www.ebi.ac.uk/pdbsum/6m66 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6m66 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PANX1_HUMAN PANX1_HUMAN]] Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.<ref>PMID:16908669</ref> <ref>PMID:20829356</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bo Z]]
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[[Category: Bo, Z]]
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[[Category: Jin Q]]
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[[Category: Jin, Q]]
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[[Category: Xiang Z]]
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[[Category: Xiang, Z]]
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[[Category: Xiaokang Z]]
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[[Category: Xiaokang, Z]]
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[[Category: Ye S]]
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[[Category: Ye, S]]
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[[Category: Atp release]]
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[[Category: Heptameric channel]]
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[[Category: Pannexin 1]]
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[[Category: Transport protein]]

Current revision

The Cryo-EM Structure of Human Pannexin 1

PDB ID 6m66

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