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2j66
From Proteopedia
(Difference between revisions)
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<StructureSection load='2j66' size='340' side='right'caption='[[2j66]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='2j66' size='340' side='right'caption='[[2j66]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2j66]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2j66]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_24 Atcc 24]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J66 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J66 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j66 OCA], [https://pdbe.org/2j66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j66 RCSB], [https://www.ebi.ac.uk/pdbsum/2j66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j66 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/BTRK_BACCI BTRK_BACCI]] Pyridoxal phosphate-dependent decarboxylase that catalyzes 1 step in the biosynthesis of the side chain of the aminoglycoside antibiotics in the biosynthetic pathway of butirosin. Able to decarboxylate L-ornithine, L-arginine, L-lysine, but not L-glutamate or any D-amino acids. Has low activity with substrates not bound to an acyl-carrier protein.<ref>PMID:15975512</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 08:02, 19 January 2022
Structural characterisation of BtrK decarboxylase from butirosin biosynthesis
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