5dy2

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Current revision (22:05, 28 June 2023) (edit) (undo)
 
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<StructureSection load='5dy2' size='340' side='right'caption='[[5dy2]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
<StructureSection load='5dy2' size='340' side='right'caption='[[5dy2]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5dy2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DY2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5DY2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5dy2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Artemisia_annua Artemisia annua]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DY2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DIN:1,6-DIHYDROXY+NAPHTHALENE'>DIN</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.57&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dxx|5dxx]], [[5dxy|5dxy]], [[5dy3|5dy3]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DIN:1,6-DIHYDROXY+NAPHTHALENE'>DIN</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Artemisinic_aldehyde_Delta(11(13))_reductase Artemisinic aldehyde Delta(11(13)) reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.92 1.3.1.92] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dy2 OCA], [https://pdbe.org/5dy2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dy2 RCSB], [https://www.ebi.ac.uk/pdbsum/5dy2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dy2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5dy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dy2 OCA], [http://pdbe.org/5dy2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dy2 RCSB], [http://www.ebi.ac.uk/pdbsum/5dy2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dy2 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DBR2_ARTAN DBR2_ARTAN]] Involved in the biosynthesis of the antimalarial endoperoxide artemisinin by catalyzing the double bond reduction of (11R)-dihydroartemisinic aldehyde to produce artemisinic aldehyde. Also able to reduce artemisinic alcohol and artemisinic acid to a lesser extent.<ref>PMID:18495659</ref>
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[https://www.uniprot.org/uniprot/DBR2_ARTAN DBR2_ARTAN] Involved in the biosynthesis of the antimalarial endoperoxide artemisinin by catalyzing the double bond reduction of (11R)-dihydroartemisinic aldehyde to produce artemisinic aldehyde. Also able to reduce artemisinic alcohol and artemisinic acid to a lesser extent.<ref>PMID:18495659</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Artemisia annua]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chen, T T]]
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[[Category: Chen TT]]
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[[Category: Li, L]]
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[[Category: Li L]]
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[[Category: Xu, Y C]]
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[[Category: Xu YC]]
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[[Category: Dbr2]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal structure of Dbr2 with mutation M27L

PDB ID 5dy2

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