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5e0a

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Current revision (22:08, 28 June 2023) (edit) (undo)
 
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<StructureSection load='5e0a' size='340' side='right'caption='[[5e0a]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='5e0a' size='340' side='right'caption='[[5e0a]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5e0a]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ebt 4ebt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E0A OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5E0A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5e0a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ebt 4ebt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E0A FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nw3|3nw3]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5e0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e0a OCA], [http://pdbe.org/5e0a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e0a RCSB], [http://www.ebi.ac.uk/pdbsum/5e0a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e0a ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e0a OCA], [https://pdbe.org/5e0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e0a RCSB], [https://www.ebi.ac.uk/pdbsum/5e0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e0a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR]] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
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[https://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Camelus dromedarius]]
[[Category: Camelus dromedarius]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Dube, D]]
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[[Category: Dube D]]
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[[Category: Kaur, P]]
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[[Category: Kaur P]]
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[[Category: Sharma, P]]
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[[Category: Sharma P]]
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[[Category: Sharma, S]]
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[[Category: Sharma S]]
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[[Category: Singh, T P]]
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[[Category: Singh TP]]
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[[Category: Sinha, M]]
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[[Category: Sinha M]]
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[[Category: Antibiotic]]
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[[Category: Antimicrobial]]
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[[Category: Immune response]]
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[[Category: Immune system]]
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[[Category: Nag]]
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[[Category: Peptidoglycan binding]]
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[[Category: Pgrp]]
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[[Category: Secreted]]
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Current revision

Crystal Structure of the complex of Camel Peptidoglycan Recognition Protein (CPGRP-S) and N-Acetylglucosamine at 2.6 A

PDB ID 5e0a

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