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2kfy
From Proteopedia
(Difference between revisions)
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<StructureSection load='2kfy' size='340' side='right'caption='[[2kfy]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2kfy' size='340' side='right'caption='[[2kfy]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2kfy]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2kfy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KFY FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2hgl|2hgl]], [[2kg0|2kg0]], [[2kg1|2kg1]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2hgl|2hgl]], [[2kg0|2kg0]], [[2kg1|2kg1]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kfy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kfy OCA], [https://pdbe.org/2kfy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kfy RCSB], [https://www.ebi.ac.uk/pdbsum/2kfy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kfy ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/HNRPF_HUMAN HNRPF_HUMAN]] Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.<ref>PMID:20526337</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:34, 27 January 2022
NMR structure of the first qRRM of hnRNP F in complex with AGGGAU G-tract RNA
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