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5etm

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Current revision (08:23, 12 July 2023) (edit) (undo)
 
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<StructureSection load='5etm' size='340' side='right'caption='[[5etm]], [[Resolution|resolution]] 1.46&Aring;' scene=''>
<StructureSection load='5etm' size='340' side='right'caption='[[5etm]], [[Resolution|resolution]] 1.46&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5etm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ETM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5ETM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5etm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ETM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ETM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5RW:2-AZANYL-8-[(4-FLUOROPHENYL)METHYLSULFANYL]-1,7-DIHYDROPURIN-6-ONE'>5RW</scene>, <scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.46&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5etk|5etk]], [[5etl|5etl]], [[5etn|5etn]], [[5eto|5eto]], [[5etp|5etp]], [[5etq|5etq]], [[5etr|5etr]], [[5ets|5ets]], [[5ett|5ett]], [[5etv|5etv]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5RW:2-AZANYL-8-[(4-FLUOROPHENYL)METHYLSULFANYL]-1,7-DIHYDROPURIN-6-ONE'>5RW</scene>, <scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folK, b0142, JW0138 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5etm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5etm OCA], [https://pdbe.org/5etm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5etm RCSB], [https://www.ebi.ac.uk/pdbsum/5etm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5etm ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine_diphosphokinase 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.3 2.7.6.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5etm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5etm OCA], [http://pdbe.org/5etm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5etm RCSB], [http://www.ebi.ac.uk/pdbsum/5etm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5etm ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HPPK_ECOLI HPPK_ECOLI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Dennis, M L]]
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[[Category: Dennis ML]]
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[[Category: Peat, T S]]
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[[Category: Peat TS]]
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[[Category: Swarbrick, J D]]
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[[Category: Swarbrick JD]]
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[[Category: Ampcpp]]
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[[Category: Complex]]
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[[Category: Inhibitor]]
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[[Category: Pyrophosphokinase]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

E. coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.46 angstrom resolution

PDB ID 5etm

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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