6k3n
From Proteopedia
(Difference between revisions)
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==Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with BPA-monoF== | ==Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with BPA-monoF== | ||
- | <StructureSection load='6k3n' size='340' side='right'caption='[[6k3n]]' scene=''> | + | <StructureSection load='6k3n' size='340' side='right'caption='[[6k3n]], [[Resolution|resolution]] 1.97Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K3N OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6k3n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K3N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6K3N FirstGlance]. <br> |
- | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.97Å</td></tr> |
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CW6:2-fluoranyl-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol'>CW6</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6k3n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k3n OCA], [https://pdbe.org/6k3n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6k3n RCSB], [https://www.ebi.ac.uk/pdbsum/6k3n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6k3n ProSAT]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/ERR3_HUMAN ERR3_HUMAN] Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).<ref>PMID:19067653</ref> <ref>PMID:18063693</ref> <ref>PMID:11864604</ref> | ||
+ | |||
+ | ==See Also== | ||
+ | *[[Estrogen-related receptor 3D structures|Estrogen-related receptor 3D structures]] | ||
+ | == References == | ||
+ | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Kakuta Y]] | [[Category: Kakuta Y]] | ||
[[Category: Matsushima A]] | [[Category: Matsushima A]] | ||
[[Category: Nose T]] | [[Category: Nose T]] |
Current revision
Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with BPA-monoF
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