7c22
From Proteopedia
(Difference between revisions)
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==Crystal structure of the C-terminal domain of SARS-CoV-2 nucleocapsid protein== | ==Crystal structure of the C-terminal domain of SARS-CoV-2 nucleocapsid protein== | ||
| - | <StructureSection load='7c22' size='340' side='right'caption='[[7c22]]' scene=''> | + | <StructureSection load='7c22' size='340' side='right'caption='[[7c22]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C22 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7C22 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7c22]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/2019-ncov 2019-ncov]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C22 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7C22 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7c22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c22 OCA], [http://pdbe.org/7c22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7c22 RCSB], [http://www.ebi.ac.uk/pdbsum/7c22 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7c22 ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7c22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c22 OCA], [http://pdbe.org/7c22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7c22 RCSB], [http://www.ebi.ac.uk/pdbsum/7c22 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7c22 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NCAP_SARS2 NCAP_SARS2]] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: 2019-ncov]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Lei J]] | + | [[Category: Lei, J]] |
| - | [[Category: Zeng R]] | + | [[Category: Zeng, R]] |
| - | [[Category: Zhou | + | [[Category: Zhou, R J]] |
| + | [[Category: Coronavirus]] | ||
| + | [[Category: Dimerization]] | ||
| + | [[Category: Nucleocapsid]] | ||
| + | [[Category: Sars-cov-2]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 10:11, 12 August 2020
Crystal structure of the C-terminal domain of SARS-CoV-2 nucleocapsid protein
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Categories: 2019-ncov | Large Structures | Lei, J | Zeng, R | Zhou, R J | Coronavirus | Dimerization | Nucleocapsid | Sars-cov-2 | Viral protein
