5hex

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<StructureSection load='5hex' size='340' side='right'caption='[[5hex]], [[Resolution|resolution]] 2.73&Aring;' scene=''>
<StructureSection load='5hex' size='340' side='right'caption='[[5hex]], [[Resolution|resolution]] 2.73&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5hex]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HEX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5HEX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5hex]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HEX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=604:5-[[(2~{R},3~{S},4~{R},5~{R},6~{S})-5-[(3-BROMOPHENYL)CARBONYLAMINO]-3,4,6-TRIS(OXIDANYL)OXAN-2-YL]METHYLSULFAMOYL]-2-METHYL-FURAN-3-CARBOXYLIC+ACID'>604</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.734&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hfu|5hfu]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=604:5-[[(2~{R},3~{S},4~{R},5~{R},6~{S})-5-[(3-BROMOPHENYL)CARBONYLAMINO]-3,4,6-TRIS(OXIDANYL)OXAN-2-YL]METHYLSULFAMOYL]-2-METHYL-FURAN-3-CARBOXYLIC+ACID'>604</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hex OCA], [https://pdbe.org/5hex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hex RCSB], [https://www.ebi.ac.uk/pdbsum/5hex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hex ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5hex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hex OCA], [http://pdbe.org/5hex PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hex RCSB], [http://www.ebi.ac.uk/pdbsum/5hex PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hex ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HXK2_HUMAN HXK2_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Hexokinase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Campobasso, N]]
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[[Category: Campobasso N]]
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[[Category: Smallwood, A]]
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[[Category: Smallwood A]]
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[[Category: Zhao, B]]
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[[Category: Zhao B]]
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[[Category: Inhibitor complex]]
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[[Category: Transferase-transferase inhibitor complex]]
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Revision as of 07:33, 9 August 2023

Crystal Structure of Human Hexokinase 2 with cmpd 30, a 2-amino-6-benzenesulfonamide glucosamine

PDB ID 5hex

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