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6jta

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Current revision (10:19, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6jta' size='340' side='right'caption='[[6jta]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='6jta' size='340' side='right'caption='[[6jta]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6jta]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JTA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6JTA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6jta]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JTA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">purL, C2273_06610, DD95_10355 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoribosylformylglycinamidine_synthase Phosphoribosylformylglycinamidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.5.3 6.3.5.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jta OCA], [https://pdbe.org/6jta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jta RCSB], [https://www.ebi.ac.uk/pdbsum/6jta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jta ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6jta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jta OCA], [http://pdbe.org/6jta PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jta RCSB], [http://www.ebi.ac.uk/pdbsum/6jta PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jta ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A0D6F9Y3_SALTM A0A0D6F9Y3_SALTM]] Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.[HAMAP-Rule:MF_00419][SAAS:SAAS01200885]
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[https://www.uniprot.org/uniprot/PUR4_SALTY PUR4_SALTY]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus typhimurium loeffler 1892]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Phosphoribosylformylglycinamidine synthase]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Ahalawat, N]]
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[[Category: Ahalawat N]]
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[[Category: Anand, R]]
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[[Category: Anand R]]
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[[Category: Mondal, J]]
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[[Category: Mondal J]]
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[[Category: Sandhu, P]]
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[[Category: Sandhu P]]
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[[Category: Sharma, N]]
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[[Category: Sharma N]]
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[[Category: Biosynthetic protein]]
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[[Category: Fgam synthetase]]
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Current revision

Crystal Structure of D464A L465A mutant of FGAM Synthetase

PDB ID 6jta

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OCA

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