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5hz8

From Proteopedia

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Current revision (11:01, 16 August 2023) (edit) (undo)
 
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<StructureSection load='5hz8' size='340' side='right'caption='[[5hz8]], [[Resolution|resolution]] 1.12&Aring;' scene=''>
<StructureSection load='5hz8' size='340' side='right'caption='[[5hz8]], [[Resolution|resolution]] 1.12&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5hz8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HZ8 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5HZ8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5hz8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HZ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HZ8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=65Z:6,8-DICHLORO-4-PHENYL-2-(PIPERIDIN-1-YL)QUINOLINE-3-CARBOXYLIC+ACID'>65Z</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.12&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FABP4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=65Z:6,8-DICHLORO-4-PHENYL-2-(PIPERIDIN-1-YL)QUINOLINE-3-CARBOXYLIC+ACID'>65Z</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5hz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hz8 OCA], [http://pdbe.org/5hz8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hz8 RCSB], [http://www.ebi.ac.uk/pdbsum/5hz8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hz8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hz8 OCA], [https://pdbe.org/5hz8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hz8 RCSB], [https://www.ebi.ac.uk/pdbsum/5hz8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hz8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FABP4_HUMAN FABP4_HUMAN]] Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity).
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[https://www.uniprot.org/uniprot/FABP4_HUMAN FABP4_HUMAN] Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ehler, A]]
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[[Category: Ehler A]]
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[[Category: Rudolph, M G]]
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[[Category: Rudolph MG]]
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[[Category: _refmac]]
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[[Category: Cytoplasm]]
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[[Category: Fatty acid binding protein]]
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[[Category: Lipid binding protein]]
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[[Category: Lipid-binding]]
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[[Category: Protein binding]]
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[[Category: Transport protein]]
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Current revision

FABP4_3 in complex with 6,8-Dichloro-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid

PDB ID 5hz8

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