This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5i4h

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:22, 23 August 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='5i4h' size='340' side='right'caption='[[5i4h]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
<StructureSection load='5i4h' size='340' side='right'caption='[[5i4h]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5i4h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I4H OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5I4H FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5i4h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I4H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5I4H FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.42&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTSL, CTSL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_L Cathepsin L], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.15 3.4.22.15] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5i4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i4h OCA], [https://pdbe.org/5i4h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5i4h RCSB], [https://www.ebi.ac.uk/pdbsum/5i4h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5i4h ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5i4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i4h OCA], [http://pdbe.org/5i4h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i4h RCSB], [http://www.ebi.ac.uk/pdbsum/5i4h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5i4h ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN]] Important for the overall degradation of proteins in lysosomes.
+
[https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 27: Line 26:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Cathepsin L]]
+
[[Category: Homo sapiens]]
-
[[Category: Human]]
+
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Sosnowski, P]]
+
[[Category: Sosnowski P]]
-
[[Category: Turk, D]]
+
[[Category: Turk D]]
-
[[Category: Cathepsin]]
+
-
[[Category: Cysteine cathepsin]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Interaction]]
+
-
[[Category: Substrate]]
+

Current revision

Caught in the Act: The Crystal Structure of cleaved Cathepsin L bound to the active site of Cathepsin L

PDB ID 5i4h

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools