2pbr
From Proteopedia
(Difference between revisions)
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<StructureSection load='2pbr' size='340' side='right'caption='[[2pbr]], [[Resolution|resolution]] 1.96Å' scene=''> | <StructureSection load='2pbr' size='340' side='right'caption='[[2pbr]], [[Resolution|resolution]] 1.96Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2pbr]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2pbr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquae Aquae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PBR FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pbr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pbr OCA], [https://pdbe.org/2pbr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pbr RCSB], [https://www.ebi.ac.uk/pdbsum/2pbr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pbr ProSAT], [https://www.topsan.org/Proteins/RSGI/2pbr TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/KTHY_AQUAE KTHY_AQUAE]] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:44, 9 March 2022
Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5
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Categories: Aquae | Large Structures | DTMP kinase | Ebihara, A | Jeyakanthan, J | Kanaujia, S P | Kuramitsu, S | Nakagawa, N | Structural genomic | Ranjani, C Vasuki | Sekar, K | Shinkai, A | Shiro, Y | Yokoyama, S | Atp-binding | Kinase | National project on protein structural and functional analyse | Nppsfa | Nucleotide biosynthesis | Rsgi | Tmp-binding | Transferase
