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2pjr
From Proteopedia
(Difference between revisions)
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<StructureSection load='2pjr' size='340' side='right'caption='[[2pjr]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='2pjr' size='340' side='right'caption='[[2pjr]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2pjr]] is a 8 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2pjr]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PJR FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pjr OCA], [https://pdbe.org/2pjr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pjr RCSB], [https://www.ebi.ac.uk/pdbsum/2pjr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pjr ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/PCRA_GEOSE PCRA_GEOSE]] DNA helicase. Has a broad nucleotide specificity, even being able to hydrolyze ethenonucleotides, and is able to couple the hydrolysis to unwinding of DNA substrates. It is a 3'-5' helicase but at high protein concentrations it can also displace a substrate with a 5' tail. Preferred substrate being one with both single and double-stranded regions of DNA. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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*[[Helicase|Helicase]] | *[[Helicase|Helicase]] | ||
*[[Helicase 3D structures|Helicase 3D structures]] | *[[Helicase 3D structures|Helicase 3D structures]] | ||
| - | *[[Molecular Playground/PcrA Helicase|Molecular Playground/PcrA Helicase]] | ||
| - | *[[PcrA helicase|PcrA helicase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 07:46, 9 March 2022
HELICASE PRODUCT COMPLEX
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