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5i5n

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<StructureSection load='5i5n' size='340' side='right'caption='[[5i5n]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
<StructureSection load='5i5n' size='340' side='right'caption='[[5i5n]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5i5n]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I5N OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5I5N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5i5n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thogoto_thogotovirus Thogoto thogotovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I5N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5I5N FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5i5o|5i5o]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.418&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5i5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i5n OCA], [http://pdbe.org/5i5n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i5n RCSB], [http://www.ebi.ac.uk/pdbsum/5i5n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5i5n ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5i5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i5n OCA], [https://pdbe.org/5i5n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5i5n RCSB], [https://www.ebi.ac.uk/pdbsum/5i5n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5i5n ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ML_THOGV ML_THOGV] Blocks host IRF3 and IRF7, thereby inhibiting IFN-beta expression and activation of host antiviral state.<ref>PMID:15582653</ref> <ref>PMID:18768974</ref> <ref>PMID:19812269</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Liang, H]]
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[[Category: Thogoto thogotovirus]]
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[[Category: Liu, Y]]
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[[Category: Liang H]]
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[[Category: Yang, M]]
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[[Category: Liu Y]]
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[[Category: Viral protein]]
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[[Category: Yang M]]

Revision as of 08:23, 23 August 2023

Crystal Structure of N-terminal Domain of Matrix Protein of Thogoto Virus at Acidic pH.

PDB ID 5i5n

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