6qvt
From Proteopedia
(Difference between revisions)
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==CMP-Sialic acid bound structure of the human wild type Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6Gal1)== | ==CMP-Sialic acid bound structure of the human wild type Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6Gal1)== | ||
| - | <StructureSection load='6qvt' size='340' side='right'caption='[[6qvt]]' scene=''> | + | <StructureSection load='6qvt' size='340' side='right'caption='[[6qvt]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QVT OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6QVT FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6qvt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QVT OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6QVT FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6qvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qvt OCA], [http://pdbe.org/6qvt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qvt RCSB], [http://www.ebi.ac.uk/pdbsum/6qvt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qvt ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NCC:CYTIDINE-5-MONOPHOSPHATE-5-N-ACETYLNEURAMINIC+ACID'>NCC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ST6GAL1, SIAT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-galactoside_alpha-2,6-sialyltransferase Beta-galactoside alpha-2,6-sialyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.99.1 2.4.99.1] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6qvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qvt OCA], [http://pdbe.org/6qvt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qvt RCSB], [http://www.ebi.ac.uk/pdbsum/6qvt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qvt ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SIAT1_HUMAN SIAT1_HUMAN]] Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.<ref>PMID:21081508</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Beta-galactoside alpha-2,6-sialyltransferase]] | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Glumoff T]] | + | [[Category: Glumoff, T]] |
| - | [[Category: Harrus D]] | + | [[Category: Harrus, D]] |
| + | [[Category: 6-sialyltransferase 1]] | ||
| + | [[Category: Beta-galactoside alpha-2]] | ||
| + | [[Category: Cmp-neu5ac]] | ||
| + | [[Category: Cmp-sia]] | ||
| + | [[Category: Cmp-sialic acid]] | ||
| + | [[Category: Cytidine-5'-monophospho-n-acetylneuraminic]] | ||
| + | [[Category: N-linked glycosylation]] | ||
| + | [[Category: Sialic acid]] | ||
| + | [[Category: Sialyltransferase]] | ||
| + | [[Category: St6gal1]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 10:37, 17 June 2020
CMP-Sialic acid bound structure of the human wild type Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6Gal1)
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Categories: Beta-galactoside alpha-2,6-sialyltransferase | Human | Large Structures | Glumoff, T | Harrus, D | 6-sialyltransferase 1 | Beta-galactoside alpha-2 | Cmp-neu5ac | Cmp-sia | Cmp-sialic acid | Cytidine-5'-monophospho-n-acetylneuraminic | N-linked glycosylation | Sialic acid | Sialyltransferase | St6gal1 | Transferase
