5izd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:39, 6 September 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='5izd' size='340' side='right'caption='[[5izd]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='5izd' size='340' side='right'caption='[[5izd]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5izd]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/"thermoplasma_acidophila"_(sic)_darland_et_al._1970 "thermoplasma acidophila" (sic) darland et al. 1970]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IZD OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IZD FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5izd]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IZD FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ta0809 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2303 "Thermoplasma acidophila" (sic) Darland et al. 1970])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5izd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5izd OCA], [https://pdbe.org/5izd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5izd RCSB], [https://www.ebi.ac.uk/pdbsum/5izd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5izd ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-glyceraldehyde_dehydrogenase_(NADP(+)) D-glyceraldehyde dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.89 1.2.1.89] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5izd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5izd OCA], [http://pdbe.org/5izd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5izd RCSB], [http://www.ebi.ac.uk/pdbsum/5izd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5izd ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/GADH_THEAC GADH_THEAC]] NADP-dependent dehydrogenase of the nED (non-phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D-glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3-phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes.<ref>PMID:16458304</ref> <ref>PMID:16566751</ref>
+
[https://www.uniprot.org/uniprot/GADH_THEAC GADH_THEAC] NADP-dependent dehydrogenase of the nED (non-phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D-glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3-phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes.<ref>PMID:16458304</ref> <ref>PMID:16566751</ref>
== References ==
== References ==
<references/>
<references/>
Line 17: Line 15:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Iermak, I]]
+
[[Category: Thermoplasma acidophilum]]
-
[[Category: Mesters, J R]]
+
[[Category: Iermak I]]
-
[[Category: Smatanova, I Kuta]]
+
[[Category: Kuta Smatanova I]]
-
[[Category: Nadp-dependent dehydrogenase]]
+
[[Category: Mesters JR]]
-
[[Category: Oxidoreductase]]
+

Current revision

Wild-type glyceraldehyde dehydrogenase from Thermoplasma acidophilum in complex with NADP

PDB ID 5izd

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools