This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5j8r

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:54, 6 September 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='5j8r' size='340' side='right'caption='[[5j8r]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
<StructureSection load='5j8r' size='340' side='right'caption='[[5j8r]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5j8r]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J8R OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5J8R FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5j8r]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J8R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5J8R FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPN12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.043&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5j8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j8r OCA], [https://pdbe.org/5j8r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5j8r RCSB], [https://www.ebi.ac.uk/pdbsum/5j8r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5j8r ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5j8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j8r OCA], [http://pdbe.org/5j8r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j8r RCSB], [http://www.ebi.ac.uk/pdbsum/5j8r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j8r ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/PTN12_HUMAN PTN12_HUMAN]] Dephosphorylates cellular tyrosine kinases, including PTK2B/PYK2, and thereby regulates signaling via PTK2B/PYK2.<ref>PMID:17329398</ref>
+
[https://www.uniprot.org/uniprot/PTN12_HUMAN PTN12_HUMAN] Dephosphorylates cellular tyrosine kinases, including PTK2B/PYK2, and thereby regulates signaling via PTK2B/PYK2.<ref>PMID:17329398</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 26: Line 25:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Protein-tyrosine-phosphatase]]
+
[[Category: Li H]]
-
[[Category: Li, H]]
+
[[Category: Sun JP]]
-
[[Category: Sun, J P]]
+
[[Category: Wang WJ]]
-
[[Category: Wang, W J]]
+
[[Category: Xiao P]]
-
[[Category: Xiao, P]]
+
[[Category: Xu YF]]
-
[[Category: Xu, Y F]]
+
[[Category: Yang F]]
-
[[Category: Yang, F]]
+
[[Category: Yu X]]
-
[[Category: Yu, X]]
+
-
[[Category: Cancer]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Tyrosine phosphorylation]]
+

Current revision

Crystal Structure of the Catalytic Domain of Human Protein Tyrosine Phosphatase non-receptor Type 12 - K61R mutant

PDB ID 5j8r

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5j8r"
Personal tools