This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5j9o

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:56, 6 September 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='5j9o' size='340' side='right'caption='[[5j9o]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
<StructureSection load='5j9o' size='340' side='right'caption='[[5j9o]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5j9o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymmo Zymmo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J9O OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5J9O FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5j9o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zymomonas_mobilis_subsp._mobilis_ZM4_=_ATCC_31821 Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5J9O FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6H8:N-[2-(METHYLAMINO)-1H-BENZIMIDAZOL-6-YL]GUANIDINE'>6H8</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.41&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5j9m|5j9m]], [[5j9n|5j9n]], [[1p0d|1p0d]], [[4puk|4puk]], [[3s1g|3s1g]], [[5i07|5i07]], [[4kwo|4kwo]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6H8:N-[2-(METHYLAMINO)-1H-BENZIMIDAZOL-6-YL]GUANIDINE'>6H8</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tgt, ZMO0363 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=264203 ZYMMO])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5j9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j9o OCA], [https://pdbe.org/5j9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5j9o RCSB], [https://www.ebi.ac.uk/pdbsum/5j9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5j9o ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA-guanine(34)_transglycosylase tRNA-guanine(34) transglycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5j9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j9o OCA], [http://pdbe.org/5j9o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j9o RCSB], [http://www.ebi.ac.uk/pdbsum/5j9o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j9o ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]
+
[https://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]
==See Also==
==See Also==
-
*[[TRNA-guanine transglycosylase|TRNA-guanine transglycosylase]]
+
*[[TRNA-guanine transglycosylase 3D structures|TRNA-guanine transglycosylase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Zymmo]]
+
[[Category: Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821]]
-
[[Category: Ehrmann, F R]]
+
[[Category: Ehrmann FR]]
-
[[Category: Heine, A]]
+
[[Category: Heine A]]
-
[[Category: Klebe, G]]
+
[[Category: Klebe G]]
-
[[Category: Benzimidazole-derivative]]
+
-
[[Category: Shigellosis]]
+
-
[[Category: Transferase]]
+
-
[[Category: Transferase inhibitor]]
+

Current revision

tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 1-(2-(methylamino)-1H-benzo[d]imidazol-6-yl)guanidine

PDB ID 5j9o

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5j9o"
Personal tools