This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5jdb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:59, 6 September 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='5jdb' size='340' side='right'caption='[[5jdb]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='5jdb' size='340' side='right'caption='[[5jdb]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5jdb]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JDB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JDB FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5jdb]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Rotavirus_A Rotavirus A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JDB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JDB FirstGlance]. <br>
-
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jdb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jdb OCA], [http://pdbe.org/5jdb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jdb RCSB], [http://www.ebi.ac.uk/pdbsum/5jdb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jdb ProSAT]</span></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.901&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jdb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jdb OCA], [https://pdbe.org/5jdb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jdb RCSB], [https://www.ebi.ac.uk/pdbsum/5jdb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jdb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/E2EA82_9REOV E2EA82_9REOV]] Outer capsid protein VP5*: forms the spike "foot" and "body". Acts as a membrane permeabilization protein that mediates release of viral particles from endosomal compartments into the cytoplasm. In integrin-dependent strains, VP5* targets the integrin heterodimer ITGA2/ITGB1 for cell attachment.[SAAS:SAAS00136874] VP8* forms the head of the spikes. It is the viral hemagglutinin and an important target of neutralizing antibodies. In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.[SAAS:SAAS00136880]
+
[https://www.uniprot.org/uniprot/E2EA82_9VIRU E2EA82_9VIRU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 17: Line 18:
</div>
</div>
<div class="pdbe-citations 5jdb" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5jdb" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 22: Line 26:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Cao, Y]]
+
[[Category: Rotavirus A]]
-
[[Category: Duan, Z]]
+
[[Category: Cao Y]]
-
[[Category: Guo, N]]
+
[[Category: Duan Z]]
-
[[Category: Jin, M]]
+
[[Category: Guo N]]
-
[[Category: Li, D]]
+
[[Category: Jin M]]
-
[[Category: Pang, L]]
+
[[Category: Li D]]
-
[[Category: Sun, X]]
+
[[Category: Pang L]]
-
[[Category: Xie, G]]
+
[[Category: Sun X]]
-
[[Category: Zhang, Q]]
+
[[Category: Xie G]]
-
[[Category: Zhou, Y]]
+
[[Category: Zhang Q]]
-
[[Category: Rotavirus]]
+
[[Category: Zhou Y]]
-
[[Category: Vaccine]]
+
-
[[Category: Viral protein]]
+
-
[[Category: Vp8]]
+

Current revision

Binding specificity of P[8] VP8* proteins of rotavirus vaccine strains with histo-blood group antigens

PDB ID 5jdb

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5jdb"
Personal tools