5jn0

<table><tr><td colspan='2'>[[5jn0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JN0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JN0 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jn0 OCA], [http://pdbe.org/5jn0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jn0 RCSB], [http://www.ebi.ac.uk/pdbsum/5jn0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jn0 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/CRK_MOUSE CRK_MOUSE]] The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

[[Category: Cho, J H]]

[[Category: Sh2 domain]]