Sandbox 20009

From Proteopedia

Revision as of 09:01, 11 June 2020

Humanized mouse antibody (hmFab) is a modified mFab which resembles more hFab.
Broadly neutralizing Fab and Neutralizing Fab are anti-HIV Fab.
Lama antibodies or nanobodies or camelid or VHH are natural single-domain antibodies containing just the heavy chain.
scFv is a single chain variable fragment in a fusion protein of the variable regions of the heavy and light chains of immunoglobulin.

3D structures of Antibody

Updated on 11-June-2020 {{#tree:id=OrganizedByTopic|openlevels=0|

• Fab

• • 7fab, 1mco, 3na9, 3lrs, 3mme, 3hi5, 1vge, 3nfs, 1ad0, 3w9d, 4nm4, 8fab, 1opg, 4fnl, 4fqh, 6n32, 1aqk, 2hff, 2agj, 3hc0, 3g6a, 3dgg, 3dif, 1b2w, 3eyo, 3eyq, 2aj3, 3fzu, 3aaz, 3gje, 5fhb, 5fha, 5f6i, 5f6h, 5drw, 5d6c, 4py7, 4ptt, 4ob5, 5szf, 5chn, 4lkc, 4hie, 4gxv, 6u85 - hFab - human
    
  • 3naa, 3nab, 3nac, 3ncj, 3o2v, 3hc3, 3hc4 - hFab (mutant)
    
  • 6b0w, 6azx, 5bk5, 5bk3 - hFab anti-circumsporozoite
    
  • 6meg, 6med, 6mee, 6mef - hFab anti-hepacivirus
    
  • 6dzn, 5vz1 - hFab anti-ebola virus
    
  • 6nis - hFab anti-zika virus
    
  • 6phg, 6phh - hFab anti-malaria
    
  • 3i75, 1nqb, 1f4w, 1aif, 1ghf, 2z91, 1ind, 3bkc, 3bkm, 1iy0, 3pp3, 3pp4, 3okm, 6fab, 2hkh, 1ay1, 1nbv, 1qbm, 1bbd, 1dsf, 1gpo, 1mnu, 1igf, 1for, 1k6q, 1bz7, 1dqd, 2ipt, 2iq9, 2iqa, 2w60, 2w9d, 3iu4, 1q9k, 1q9l, 1q9o, 2z4q, 1cl7, 1cr9, 1r24, 1gig, 1uyw, 1cgs, 2cgr, 1q0x, 1ibg, 3eo0, 2op4, 2q76, 2ojz, 2g60, 2dbl, 1dbj, 1dbk, 1dbm, 1dba, 1mrc, 2gcy, 1flr, 1uz6, 1rfd, 1t2q, 1ggb, 1ggc, 1bm3, 2eh7, 2fat, 3cfc, 1fl3, 3cfe, 4j1u, 4gq9, 3qg7, 3rvt, 3s62, 4gay, 5mx3, 5l88, 5i66, 5cma, 5az2, 4z0b, 4qth, 4poz, 5vzr, 5lgh, 5l9d, 5l7x, 5h2b, 4lci, 4k23, 6p79 - mFab – mouse
    
  • 3eot, 2d03, 3esv, 3et9 – mFab (mutant)
    
  • 3iy2, 3iy3, 3iy4, 3iy5, 3iy6, 3iy7 - mFab – Cryo EM
    
  • 1jpt, 3mxv, 2o5x, 1ucb, 1bbj, 1t04, 2fgw, 1fvd, 1fve, 4kuz, 6l8t - hmFab
    
  • 1cqk – mFab MAK33 CH3 domain
    
  • 6a0x - mFab anti-influenza virus
    
  • 6h3h - mFab anti-fullerene
    
  • 6pyc - mFab anti-kappa
    
  • 6pyd - mFab anti-marinobufagenin
    
  • 6idh, 6kdh - mFab anti-photoproduct
    
  • 3mj8, 3r06 – AhFab – Armenian hamster
    
  • 3iy1, 1zan – raFab – rat
    
  • 4k3e, 4k3d – bFab – bovine
    
  • 6e8v – bFab-1
    
  • 6e9g – bFab-2
    
  • 6e9h – bFab-3
    
  • 6e9i – bFab-4
    
  • 6e9k – bFab-5
    
  • 6e9q – bFab-6
    
  • 6e9u – bFab-7
    
  • 4b41, 4m3j – LgFab – Lama glama
    
  • 6df0, 6dez - syFab anti-phosphotyrosine - synthetic
    

• Anti-HIV Fab

• • 1rz7, 1rz8, 1rzf, 1rzg, 1rzi, 3mlj, 3mug, 3qeh, 3ttn, rpi, 3tnm, 4fz8, 4f58, 4f57, 4f5a, 5iie, 5dt1, 5cey, 5cex, 5cck, 5bzw, 5bzd, 4rqq, 5uy3, 4qf1, 6mtr, 6mts - hFab
    
  • 3nz8, 3o6k, 3ntc, 3qeg – mFab
    
  • 5kg9 – hmFab
    
  • 5dd6, 5dd5, 5dd3, 5dd1, 4rfe, 4q2z, 5t4z – rmFab – rhesus macaque
    

• Human Fab: small molecule complex

• • 3o2w - hFab 1e9 (mutant) + transition state analog
    
  • 3oau – hFab 2g12 (mutant) + mannose
    
  • 4ptu, 4hih – hFab + rhamnose
    
  • 1ikf – hFab R45 + cyclosporin
    
  • 3oay, 3oaz, 3ob0, 6msy, 6mub, [[6mu3], 6mnf - hFab 2g12 + glycan
    

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