WWP2
From Proteopedia
(Difference between revisions)
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| - | <scene name='84/848928/Linker/8'>Text To Be Displayed</scene><scene name='84/848928/Linker/3'>Text To Be Displayed</scene>[[Image:WWP2 F2Scene.png|300px|right|thumb| WWP2 Overall]] | + | <scene name='84/848928/Linker/9'>Text To Be Displayed</scene><scene name='84/848928/Linker/8'>Text To Be Displayed</scene><scene name='84/848928/Linker/3'>Text To Be Displayed</scene>[[Image:WWP2 F2Scene.png|300px|right|thumb| WWP2 Overall]] |
==Introduction== | ==Introduction== | ||
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<scene name='84/848928/Linker/3'>Green link</scene><scene name='84/848928/Linker/4'>Text To Be Displayed</scene> for Scene F1 | <scene name='84/848928/Linker/3'>Green link</scene><scene name='84/848928/Linker/4'>Text To Be Displayed</scene> for Scene F1 | ||
| - | 17-142 is C2 Domain | + | 17-142 is<scene name='84/848928/Linker/9'> C2 Domain</scene> |
302-361 is WW1 and WW2 | 302-361 is WW1 and WW2 | ||
361-407 is 2,3 Linker | 361-407 is 2,3 Linker | ||
Revision as of 19:33, 15 June 2020
Contents |
Introduction
WWP2 is a family member of Homologous to the E6-AP Carboxyl Terminus (HECT) E3 Ligases which accept a ubiquitin molecule from an enzyme upstream in the ubiquitination pathway and transfer the ubiquitin to a target signaling molecule or transcription factor. The thioester bond formation between an active site Cystine on HECT E3 Ligases and ubiquitin differentiates this family of enzymes from the more abundant RING family of ubiquitin ligases which do not covalently bond to the ubiquitin ligand. ---
Structure
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Function
Disease
Relevance
Structural highlights
References
Proteopedia Page Contributors and Editors (what is this?)
Tihitina Y Aytenfisu, Hannah Campbell, Sandra B. Gabelli, Michal Harel
