2roo
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='2roo' size='340' side='right'caption='[[2roo]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2roo' size='340' side='right'caption='[[2roo]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2roo]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ROO OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[2roo]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ROO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ROO FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2roo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2roo OCA], [https://pdbe.org/2roo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2roo RCSB], [https://www.ebi.ac.uk/pdbsum/2roo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2roo ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/TXMG4_MACGS TXMG4_MACGS]] Selectively slows channel inactivation of mammalian Nav1.1/SCN1A, Nav1.3/SCN3A, and Nav1.6/SCN8A and shows higher affinity for insect Nav1/para channels (site 3). Induces tonic repetitive firing of nerve impulses in insect neurons accompanied by plateau potentials.<ref>PMID:12860384</ref> <ref>PMID:19592486</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 06:54, 16 March 2022
Solution structure of Magi4, a spider toxin from Macrothele gigas
| |||||||||||
