1d4s
From Proteopedia
(New page: 200px<br /> <applet load="1d4s" size="450" color="white" frame="true" align="right" spinBox="true" caption="1d4s, resolution 2.5Å" /> '''HIV-1 PROTEASE V82F/...) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:1d4s. | + | [[Image:1d4s.jpg|left|200px]]<br /><applet load="1d4s" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="1d4s" size=" | + | |
caption="1d4s, resolution 2.5Å" /> | caption="1d4s, resolution 2.5Å" /> | ||
'''HIV-1 PROTEASE V82F/I84V DOUBLE MUTANT/TIPRANAVIR COMPLEX'''<br /> | '''HIV-1 PROTEASE V82F/I84V DOUBLE MUTANT/TIPRANAVIR COMPLEX'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
| - | 1D4S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with TPV as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http:// | + | 1D4S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=TPV:'>TPV</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D4S OCA]. |
==Reference== | ==Reference== | ||
| Line 19: | Line 18: | ||
[[Category: hydrolase]] | [[Category: hydrolase]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Feb 15 15:38:33 2008'' |
Revision as of 13:38, 15 February 2008
|
HIV-1 PROTEASE V82F/I84V DOUBLE MUTANT/TIPRANAVIR COMPLEX
About this Structure
1D4S is a Single protein structure of sequence from Human immunodeficiency virus 1 with as ligand. Active as HIV-1 retropepsin, with EC number 3.4.23.16 Full crystallographic information is available from OCA.
Reference
Structure-based design of HIV protease inhibitors: sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrones as non-peptidic inhibitors., Thaisrivongs S, Skulnick HI, Turner SR, Strohbach JW, Tommasi RA, Johnson PD, Aristoff PA, Judge TM, Gammill RB, Morris JK, Romines KR, Chrusciel RA, Hinshaw RR, Chong KT, Tarpley WG, Poppe SM, Slade DE, Lynn JC, Horng MM, Tomich PK, Seest EP, Dolak LA, Howe WJ, Howard GM, Watenpaugh KD, et al., J Med Chem. 1996 Oct 25;39(22):4349-53. PMID:8893827
Page seeded by OCA on Fri Feb 15 15:38:33 2008
