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2vwe

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<StructureSection load='2vwe' size='340' side='right'caption='[[2vwe]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
<StructureSection load='2vwe' size='340' side='right'caption='[[2vwe]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2vwe]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VWE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2VWE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2vwe]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VWE FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2c7w|2c7w]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2c7w|2c7w]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2vwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vwe OCA], [http://pdbe.org/2vwe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vwe RCSB], [http://www.ebi.ac.uk/pdbsum/2vwe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vwe ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vwe OCA], [https://pdbe.org/2vwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vwe RCSB], [https://www.ebi.ac.uk/pdbsum/2vwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vwe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/VEGFB_HUMAN VEGFB_HUMAN]] Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
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[[https://www.uniprot.org/uniprot/VEGFB_HUMAN VEGFB_HUMAN]] Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 11:47, 30 March 2022

Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralizing Antibody Fab Fragment

PDB ID 2vwe

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