5jyh

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==Solution Structure of Hge36: Scorpine-like Peptide from Hadrurus Gertschi==
==Solution Structure of Hge36: Scorpine-like Peptide from Hadrurus Gertschi==
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<StructureSection load='5jyh' size='340' side='right'caption='[[5jyh]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='5jyh' size='340' side='right'caption='[[5jyh]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5jyh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hofge Hofge]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JYH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JYH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5jyh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hadrurus_gertschi Hadrurus gertschi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JYH FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jyh OCA], [http://pdbe.org/5jyh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jyh RCSB], [http://www.ebi.ac.uk/pdbsum/5jyh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jyh ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jyh OCA], [https://pdbe.org/5jyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jyh RCSB], [https://www.ebi.ac.uk/pdbsum/5jyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jyh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/KBX3_HADGE KBX3_HADGE]] Hge-scorpine has antibacterial activity against B.subtilis, but not against S.aureus. Also has hemolytic and cytolytic activities.<ref>PMID:18030427</ref> Hge36 peptide blocks Kv1.1/KCNA1 (IC(50)=185 nM) potassium channels. Shows a weak hemolytic activity.<ref>PMID:18030427</ref>
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[https://www.uniprot.org/uniprot/KBX3_HOFGE KBX3_HOFGE] Has antibacterial activity against B.subtilis, but not against S.aureus. Also has hemolytic and cytolytic activities.<ref>PMID:18030427</ref> Blocks Kv1.1/KCNA1 (IC(50)=185 nM) potassium channels. Shows a weak hemolytic activity.<ref>PMID:18030427</ref> <ref>PMID:27314815</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Hofge]]
 
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[[Category: Large Structures]]
 
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[[Category: Flores-Solis, D]]
 
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[[Category: Rio-Portilla, F del]]
 
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[[Category: Vega, R Rodriguez De La]]
 
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[[Category: Antiparasitic activity]]
 
[[Category: Hadrurus gertschi]]
[[Category: Hadrurus gertschi]]
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[[Category: Scorpine-like peptide]]
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[[Category: Large Structures]]
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[[Category: Toxin]]
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[[Category: Flores-Solis D]]
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[[Category: Rodriguez De La Vega R]]
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[[Category: Del Rio-Portilla F]]

Revision as of 19:15, 20 September 2023

Solution Structure of Hge36: Scorpine-like Peptide from Hadrurus Gertschi

PDB ID 5jyh

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