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CAMP-dependent protein kinase 3D structures

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**[[3ag9]] - bPKA + inhibitor<br />
**[[3ag9]] - bPKA + inhibitor<br />
**[[5n1f]], [[5n1g]], [[5n1h]], [[5n3g]], [[5n3h]], [[5n3i]], [[5n3j]], [[5n3k]], [[5n3l]], [[5n3m]], [[5n3n]], [[5n3o]], [[5n3p]], [[5n3q]], [[5n3r]], [[5n3s]], [[5n3t]] - haPKA + fragment molecule<br />
**[[5n1f]], [[5n1g]], [[5n1h]], [[5n3g]], [[5n3h]], [[5n3i]], [[5n3j]], [[5n3k]], [[5n3l]], [[5n3m]], [[5n3n]], [[5n3o]], [[5n3p]], [[5n3q]], [[5n3r]], [[5n3s]], [[5n3t]] - haPKA + fragment molecule<br />
-
**[[6em2]] - haPKA + fasudil<br />
+
**[[6em2]], [[6sq1]] - haPKA + drug<br />
 +
**[[6snn]], [[6snx]], [[6sox]], [[6spm]], [[6sps]], [[6spu]], [[6z44]] - haPKA + benzoic acid derivative<br />
 +
**[[6spy]] - haPKA + pyridine derivative<br />
 +
**[[6zn0]] - haPKA + nicotinamide derivative<br />
**[[4ntt]] – mPKA (mutant) + ADP<br />
**[[4ntt]] – mPKA (mutant) + ADP<br />
**[[1bkx]] – mPKA + adenosine<br />
**[[1bkx]] – mPKA + adenosine<br />
Line 39: Line 42:
**[[4iac]], [[4iad]], [[4iaf]], [[4iai]], [[4iak]], [[4iay]], [[4iaz]], [[4ib0]] - mPKA + PSP20 peptide<br />
**[[4iac]], [[4iad]], [[4iaf]], [[4iai]], [[4iak]], [[4iay]], [[4iaz]], [[4ib0]] - mPKA + PSP20 peptide<br />
**[[4ib1]], [[4ib3]], [[4o22]] – mPKA + SP20 peptide<br />
**[[4ib1]], [[4ib3]], [[4o22]] – mPKA + SP20 peptide<br />
-
**[[6mm5]] – mPKA + RYR2 peptide<br />
+
**[[6mm5]] – mPKA + ryanodine receptor 2 peptide<br />
-
**[[6mm6]], [[6mm7]], [[6mm8]] – mPKA + RYR2 phosphorylation domain<br />
+
**[[6mm6]], [[6mm7]], [[6mm8]] – mPKA + ryanodine receptor 2 phosphorylation domain<br />
**[[4wb5]], [[4wb6]], [[4wb8]] – mPKA (mutant) + PKI peptide<br />
**[[4wb5]], [[4wb6]], [[4wb8]] – mPKA (mutant) + PKI peptide<br />
**[[4wih]], [[5lcp]], [[5lcq]], [[5lcr]], [[5lct]], [[5lcu]], [[5m0u]] - haPKA + peptide inhibitor <br />
**[[4wih]], [[5lcp]], [[5lcq]], [[5lcr]], [[5lct]], [[5lcu]], [[5m0u]] - haPKA + peptide inhibitor <br />
 +
**[[6y2u]], [[6yna]], [[6ynb]], [[6ync]], [[6ynt]], [[6ypp]], [[6yqi]], [[6yqj]], [[6yqk]] – haPKA + PKI peptide + drug<br />
 +
**[[6y0b]], [[6y2o]], [[6y89]], [[6ynr]], [[6yot]] – haPKA + PKI peptide + inhibitor<br />
*PKA catalytic subunit ternary complex
*PKA catalytic subunit ternary complex
Line 65: Line 70:
**[[5mhi]], [[5n1d]], [[5n1e]], [[5n1k]], [[5n1l]], [[5n1m]], [[5n1n]], [[5n1o]], [[5n32]], [[5n33]], [[5n36]], [[5n37]], [[5n39]], [[5n3a]], [[5n3b]], [[5n3c]], [[5n3d]], [[5n3e]], [[5n3f]], [[5n7p]], [[5n7u]] - haPKA + peptide inhibitor + fragment molecule<br />
**[[5mhi]], [[5n1d]], [[5n1e]], [[5n1k]], [[5n1l]], [[5n1m]], [[5n1n]], [[5n1o]], [[5n32]], [[5n33]], [[5n36]], [[5n37]], [[5n39]], [[5n3a]], [[5n3b]], [[5n3c]], [[5n3d]], [[5n3e]], [[5n3f]], [[5n7p]], [[5n7u]] - haPKA + peptide inhibitor + fragment molecule<br />
**[[6f14]], [[6frx]], [[6erv]], [[6eru]], [[6ert]], [[6i2h]], [[6emd]], [[6i2b]], [[6eh3]], [[6egw]], [[5ous]], [[5ouc]], [[5oua]], [[5otg]], [[5ot3]], [[5ol3]], [[5ok3]], [[5o5m]], [[5o0e]], [[5nw8]], [[5ntj]] - haPKA + peptide inhibitor + inhibitor<br />
**[[6f14]], [[6frx]], [[6erv]], [[6eru]], [[6ert]], [[6i2h]], [[6emd]], [[6i2b]], [[6eh3]], [[6egw]], [[5ous]], [[5ouc]], [[5oua]], [[5otg]], [[5ot3]], [[5ol3]], [[5ok3]], [[5o5m]], [[5o0e]], [[5nw8]], [[5ntj]] - haPKA + peptide inhibitor + inhibitor<br />
-
**[[6erw]], [[6ers]], [[6emb]], [[5m75]], [[5m71]], [[5m6y]], [[5m6v]], [[5m0l]], [[5m0c]], [[5m0b]] - haPKA + peptide inhibitor + fasudil derivative<br />
+
**[[6erw]], [[6ers]], [[6emb]], [[5m75]], [[5m71]], [[5m6y]], [[5m6v]], [[5m0l]], [[5m0c]], [[5m0b]] - haPKA + peptide inhibitor + drug<br />
-
**[[6i2a]] - haPKA + RPK153 + fasudil <br />
+
**[[6i2a]] - haPKA + RPK153 + drug <br />
-
**[[6i2c]], [[6i2d]] - haPKA + RPK182 + fasudil <br />
+
**[[6i2c]], [[6i2d]] - haPKA + RPK182 + drug <br />
*PKA catalytic subunit ternary complex with nucleotide
*PKA catalytic subunit ternary complex with nucleotide
Line 81: Line 86:
**[[6esa]] - haPKA + peptide inhibitor + ribose + AMP<br />
**[[6esa]] - haPKA + peptide inhibitor + ribose + AMP<br />
**[[6ema]] - haPKA + peptide inhibitor + inhibitor + ATP<br />
**[[6ema]] - haPKA + peptide inhibitor + inhibitor + ATP<br />
 +
**[[6y8c]] – haPKA + PKI peptide + ATP<br />
 +
**[[6y05]] – haPKA + PKI peptide + Adenine<br />
-
*PKA regulatory subunit
+
*'''PKA regulatory subunit'''
**[[4f9k]] – hPKA I-β<br />
**[[4f9k]] – hPKA I-β<br />
Line 92: Line 99:
**[[1r2a]] - mPKA II dimerization-anchoring domain – NMR<br />
**[[1r2a]] - mPKA II dimerization-anchoring domain – NMR<br />
**[[1l6e]] - mPKA II-α dimerization-anchoring domain – NMR<br />
**[[1l6e]] - mPKA II-α dimerization-anchoring domain – NMR<br />
-
**[[3of1]] - yPKA <br />
+
**[[3of1]], [[6xqk]] - yPKA <br />
*PKA regulatory subunit binary complex
*PKA regulatory subunit binary complex
Line 108: Line 115:
**[[5t3n]] - PfPKA + cAMP derivative – ''Plasmodium falciparum''<br />
**[[5t3n]] - PfPKA + cAMP derivative – ''Plasmodium falciparum''<br />
**[[5kbf]], [[5k8s]] - PfPKA + cAMP <br />
**[[5kbf]], [[5k8s]] - PfPKA + cAMP <br />
 +
**[[6h4g]] - PKA (mutant) + cAMP – ''Trypanosoma brucei''<br />
 +
**[[6rsx]] - PKA + cAMP – ''Euglena gracilis''<br />
*PKA regulatory subunit ternary complex
*PKA regulatory subunit ternary complex

Revision as of 07:10, 24 May 2021

3D structures of cAMP-dependent protein kinase

Updated on 24-May-2021

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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