2j1p

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(New page: 200px<br /> <applet load="2j1p" size="450" color="white" frame="true" align="right" spinBox="true" caption="2j1p, resolution 1.80&Aring;" /> '''GERANYLGERANYL DIPH...)
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==About this Structure==
==About this Structure==
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2J1P is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Sinapis_alba Sinapis alba]] with GRG, PGO and BME as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2J1P OCA]].
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2J1P is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Sinapis_alba Sinapis alba]] with GRG, PGO and BME as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2J1P OCA]].
==Reference==
==Reference==
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[[Category: transit peptide]]
[[Category: transit peptide]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 17:52:38 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:25:46 2007''

Revision as of 09:21, 30 October 2007


2j1p, resolution 1.80Å

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GERANYLGERANYL DIPHOSPHATE SYNTHASE FROM SINAPIS ALBA IN COMPLEX WITH GGPP

Overview

The crystal structure of the geranylgeranyl diphosphate synthase from, Sinapis alba (mustard) has been solved in two crystal forms at 1.8 and 2.0, A resolutions. In one of these forms, the dimeric enzyme binds one, molecule of the final product geranylgeranyl diphosphate in one subunit., The chainfold of the enzyme corresponds to that of other members of the, farnesyl diphosphate synthase family. Whereas the binding modes of the two, substrates dimethylallyl diphosphate and isopentenyl diphosphate at the, allyl and isopentenyl sites, respectively, have been established with, other members of the family, the complex structure presented reveals for, the first time the binding mode of a reaction product at the isopentenyl, site. The binding geometry of substrates and product in conjunction ... [(full description)]

About this Structure

2J1P is a [Single protein] structure of sequence from [Sinapis alba] with GRG, PGO and BME as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].

Reference

Structure and Reaction Geometry of Geranylgeranyl Diphosphate Synthase from Sinapis alba(,)., Kloer DP, Welsch R, Beyer P, Schulz GE, Biochemistry. 2006 Dec 26;45(51):15197-204. Epub 2006 Dec 1. PMID:17176041

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