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2x29
From Proteopedia
(Difference between revisions)
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<StructureSection load='2x29' size='340' side='right'caption='[[2x29]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='2x29' size='340' side='right'caption='[[2x29]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2x29]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2x29]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2wak 2wak]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X29 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X29 FirstGlance]. <br> |
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x29 OCA], [https://pdbe.org/2x29 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x29 RCSB], [https://www.ebi.ac.uk/pdbsum/2x29 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x29 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/TNFL9_HUMAN TNFL9_HUMAN]] Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Current revision
Crystal structure of human4-1BB ligand ectodomain
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