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2xhb

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<StructureSection load='2xhb' size='340' side='right'caption='[[2xhb]], [[Resolution|resolution]] 2.72&Aring;' scene=''>
<StructureSection load='2xhb' size='340' side='right'caption='[[2xhb]], [[Resolution|resolution]] 2.72&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xhb]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_700654 Atcc 700654]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XHB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2XHB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xhb]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_700654 Atcc 700654]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XHB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XHB FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DI:2-DEOXYINOSINE-5-MONOPHOSPHATE'>DI</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DI:2-DEOXYINOSINE-5-MONOPHOSPHATE'>DI</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1wn7|1wn7]], [[2vwk|2vwk]], [[2vwj|2vwj]], [[1tgo|1tgo]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1wn7|1wn7]], [[2vwk|2vwk]], [[2vwj|2vwj]], [[1tgo|1tgo]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2xhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xhb OCA], [http://pdbe.org/2xhb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xhb RCSB], [http://www.ebi.ac.uk/pdbsum/2xhb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xhb ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xhb OCA], [https://pdbe.org/2xhb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xhb RCSB], [https://www.ebi.ac.uk/pdbsum/2xhb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xhb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DPOL_THEGO DPOL_THEGO]] In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity.
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[[https://www.uniprot.org/uniprot/DPOL_THEGO DPOL_THEGO]] In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 2xhb" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2xhb" style="background-color:#fffaf0;"></div>
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==See Also==
 
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
 
== References ==
== References ==
<references/>
<references/>

Revision as of 10:52, 13 April 2022

Crystal structure of DNA polymerase from Thermococcus gorgonarius in complex with hypoxanthine-containing DNA

PDB ID 2xhb

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