Endonuclease 3D structures

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Line 71: Line 71:
**[[1k3x]], [[2ea0]], [[1k3w]], [[1k3x]], [[2ea0]], [[2opf]], [[2oq4]] - EcENN + DNA <br />
**[[1k3x]], [[2ea0]], [[1k3w]], [[1k3x]], [[2ea0]], [[2opf]], [[2oq4]] - EcENN + DNA <br />
**[[2opf]], [[2oq4]], [[6fbu]] - EcENN (mutant) + DNA
**[[2opf]], [[2oq4]], [[6fbu]] - EcENN (mutant) + DNA
 +
 +
*ENN-VIII-like
 +
 +
**[[6lwa]], [[6lwb]], [[6lwc]], [[6lwd]], [[6lwf]], [[6lwf]], [[6lwg]], [[6lwh]], [[6lwi]], [[6lwj]], [[6lwl]], [[6lwk]], [[6lwm]], [[6lwn]], [[6lwo]], [[6lwp]], [[6lwq]], [[6lwr]] – hENN + DNA<br />
*AP ENN
*AP ENN
Line 89: Line 93:
**[[3oq2]] – Cas2 – ''Desulfovibrio vulgaris''<br />
**[[3oq2]] – Cas2 – ''Desulfovibrio vulgaris''<br />
**[[4mak]] – EcCas2<br />
**[[4mak]] – EcCas2<br />
 +
**[[6jhz]] – EcCas2 + peptide<br />
**[[4p6i]], [[4qdl]] – EcCas1 + EcCas2<br />
**[[4p6i]], [[4qdl]] – EcCas1 + EcCas2<br />
**[[6qy3]] – GsCas1 + EcCas2 + Csn2 – Cryo EM<br />
**[[6qy3]] – GsCas1 + EcCas2 + Csn2 – Cryo EM<br />
Line 104: Line 109:
**[[3i4h]] – PfCas6 - ''Pyrococcus furiosus''<br />
**[[3i4h]] – PfCas6 - ''Pyrococcus furiosus''<br />
**[[4dzd]] – EcCas6e<br />
**[[4dzd]] – EcCas6e<br />
 +
**[[7jzx]] – PaCas6f in crispr-Cas surveillance complex – Cryo EM<br />
**[[4qr0]], [[4qr1]] - SpCas9 (Csn1) – ''Streptococcus pyogenes''<br />
**[[4qr0]], [[4qr1]] - SpCas9 (Csn1) – ''Streptococcus pyogenes''<br />
**[[4qr0]], [[4qr1]], [[4cmp]], [[4cmq]] - SpCas9 <br />
**[[4qr0]], [[4qr1]], [[4cmp]], [[4cmq]] - SpCas9 <br />
Line 112: Line 118:
**[[3w2w]] – PfCas10 CMR2+CMR3 subunits + ATP<br />
**[[3w2w]] – PfCas10 CMR2+CMR3 subunits + ATP<br />
**[[4gkf]] – PfCas10 CMR5 subunit<br />
**[[4gkf]] – PfCas10 CMR5 subunit<br />
 +
**[[6w62]] – Cas12i + RNA – ''Lachnospiraceae bacterium'' – Cryo EM<br />
**[[4an8]], [[4f3e]] – TtCasA (Cse1)<br />
**[[4an8]], [[4f3e]] – TtCasA (Cse1)<br />
**[[4h3t]] - CasA (Cse1) – ''Acidimicrobium ferrooxidans''<br />
**[[4h3t]] - CasA (Cse1) – ''Acidimicrobium ferrooxidans''<br />
Line 127: Line 134:
**[[5wfe]] – EcCas1 + EcCas2 + IHF-a + IHF-b + DNA<br />
**[[5wfe]] – EcCas1 + EcCas2 + IHF-a + IHF-b + DNA<br />
**[[5xvp]], [[5xvo]], [[5xvn]] – Cas1 + Cas2 + DNA – ''Enterococcus faecalis''<br />
**[[5xvp]], [[5xvo]], [[5xvn]] – Cas1 + Cas2 + DNA – ''Enterococcus faecalis''<br />
 +
**[[7cr6]], [[7cr8]] – Cas1 + Cas2 + DNA – ''Synechocystis''<br />
**[[6qxt]], [[6qxf]] – GsCas1 (mutant) + EcCas2 + Csn2 + DNA – Cryo EM<br />
**[[6qxt]], [[6qxf]] – GsCas1 (mutant) + EcCas2 + Csn2 + DNA – Cryo EM<br />
**[[6kdv]] – TtCas1 + DNA <br />
**[[6kdv]] – TtCas1 + DNA <br />
Line 160: Line 168:
**[[6je4]] - NmCas9 + RNA + DNA + AcriiC3<br />
**[[6je4]] - NmCas9 + RNA + DNA + AcriiC3<br />
**[[6rj9]], [[6rja]], [[6rjg]] - StCas9 + RNA + DNA + AcriiA6 – ''Streptococcus thermophilus''<br />
**[[6rj9]], [[6rja]], [[6rjg]] - StCas9 + RNA + DNA + AcriiA6 – ''Streptococcus thermophilus''<br />
-
**[[6rjd]] - StCas9 + RNA + DNA<br />
+
**[[6rjd]], [[6m0v]], [[6m0w]], [[6m0x]] - StCas9 + RNA + DNA<br />
**[[5x2h]], [[5x2g]] – Cas9 + RNA + DNA – ''Campylobacter jejuni''<br />
**[[5x2h]], [[5x2g]] – Cas9 + RNA + DNA – ''Campylobacter jejuni''<br />
**[[5czz]] - SaCas9 (Csn1) + RNA + DNA - ''Staphylococcus aureus''<br />
**[[5czz]] - SaCas9 (Csn1) + RNA + DNA - ''Staphylococcus aureus''<br />
**[[5axw]] - SaCas9 (Csn1) (mutant) + RNA + DNA <br />
**[[5axw]] - SaCas9 (Csn1) (mutant) + RNA + DNA <br />
-
**[[6joo]] - Cas9 + RNA + DNA – Corynebacterium diphtheriae<br />
+
**[[6joo]] - Cas9 + RNA + DNA – ''Corynebacterium diphtheriae''<br />
**[[5b2o]], [[5b2p]], [[5b2q]] - FtCas9 (mutant) + RNA + DNA – ''Francisella tularensis''<br />
**[[5b2o]], [[5b2p]], [[5b2q]] - FtCas9 (mutant) + RNA + DNA – ''Francisella tularensis''<br />
 +
**[[6wc0]] - Cas9 + RNA + DNA – ''Acidothermus cellulolyticus''<br />
**[[6i1l]], [[6i1k]], [[6gtg]], [[6gtf]], [[6gte]], [[6gtd]], [[6gtc]] – FtCas12a (mutant) + RNA + DNA <br />
**[[6i1l]], [[6i1k]], [[6gtg]], [[6gtf]], [[6gte]], [[6gtd]], [[6gtc]] – FtCas12a (mutant) + RNA + DNA <br />
 +
**[[6w62]] – Cas12i + RNA – ''Lachnospiraceae bacterium'' – Cryo EM<br />
**[[4u7u]] – EcCasA (Cse1) + CasB + CasC + CasD + CasE + RNA<br />
**[[4u7u]] – EcCasA (Cse1) + CasB + CasC + CasD + CasE + RNA<br />
**[[4qyz]], [[5h9f]], [[5h9e]] – EcCasA (Cse1) + CasB + CasC + CasD + CasE + RNA + DNA<br />
**[[4qyz]], [[5h9f]], [[5h9e]] – EcCasA (Cse1) + CasB + CasC + CasD + CasE + RNA + DNA<br />
Line 213: Line 223:
**[[6p4o]], [[6p4w]] – StENN + DNA-dependent ATPase XPBII – ''Sulfurisphera tokidaii''<br />
**[[6p4o]], [[6p4w]] – StENN + DNA-dependent ATPase XPBII – ''Sulfurisphera tokidaii''<br />
-
**[[6p4o]] – StENN + DNA-dependent ATPase XPBII + DNA<br />
+
**[[6p4f]] – StENN + DNA-dependent ATPase XPBII + DNA<br />
**[[6p66]] – AfENN + Rad25<br />
**[[6p66]] – AfENN + Rad25<br />
Line 241: Line 251:
**[[2gw6]] – hENN subunit sen15 – NMR<br />
**[[2gw6]] – hENN subunit sen15 – NMR<br />
 +
**[[6z9u]] – hENN subunits sen15+sen34<br />
**[[1a79]], [[1a76]], [[1a77]] - MjENN – ''Methanocaldococcus jannaschii''<br />
**[[1a79]], [[1a76]], [[1a77]] - MjENN – ''Methanocaldococcus jannaschii''<br />
**[[2cv8]] - ENN – ''Sulfolobus tokodaii''<br />
**[[2cv8]] - ENN – ''Sulfolobus tokodaii''<br />
Line 345: Line 356:
**[[4zou]] – hENN SLX4 subunit BTB domain<br />
**[[4zou]] – hENN SLX4 subunit BTB domain<br />
**[[4uyi]] – hENN SLX4 subunit BTB domain (mutant)<br />
**[[4uyi]] – hENN SLX4 subunit BTB domain (mutant)<br />
 +
**[[7cq4]] – yENN SLX1 (mutant)+SLX4 subunits + DNA<br />
**[[4xm5]] – CgENN SLX1 subunit – ''Candida glabrata''<br />
**[[4xm5]] – CgENN SLX1 subunit – ''Candida glabrata''<br />
**[[4xlg]] – CgENN SLX1 (mutant)+SLX4 subunits<br />
**[[4xlg]] – CgENN SLX1 (mutant)+SLX4 subunits<br />
Line 381: Line 393:
**[[5cxr]] – ENN + pyrazole derivative – Influenza virus <br />
**[[5cxr]] – ENN + pyrazole derivative – Influenza virus <br />
**[[6j9l]]] - NmENN + AcriiC2 <br />
**[[6j9l]]] - NmENN + AcriiC2 <br />
 +
**[[6yex]] – VcENN – ''Vibrio campbellii''<br />
 +
**[[6yjb]], [[6ykf]], [[6ymg]] – VcENN + DNA<br />
*UV damage ENN
*UV damage ENN
Line 417: Line 431:
**[[2ziw]], [[2zix]], [[2ziu]] – hENN EME1 + Mus81<br />
**[[2ziw]], [[2zix]], [[2ziu]] – hENN EME1 + Mus81<br />
**[[2ziv]] – hENN EME1 (mutant) + Mus81<br />
**[[2ziv]] – hENN EME1 (mutant) + Mus81<br />
 +
**[[6vwb]] – hENN Mus81 N-terminal - NMR<br />
**[[4p0p]], [[4p0q]], [[4p0r]], [[4p0s]] – hENN EME1 + Mus81 + DNA<br />
**[[4p0p]], [[4p0q]], [[4p0r]], [[4p0s]] – hENN EME1 + Mus81 + DNA<br />
**[[2kpf]] - mENN – mouse<br />
**[[2kpf]] - mENN – mouse<br />
Line 465: Line 480:
*ENN G
*ENN G
-
**[[6njt]] – mENN (mutant)<br />
+
**[[6lyf]], [[6m3f]], [[6m3t]], [[6njt]] – mENN (mutant)<br />
**[[6nju]] – mENN (mutant) + DNA<br />
**[[6nju]] – mENN (mutant) + DNA<br />
**[[5gkc]], [[4qn0]] – CeENN (mutant) – ''Caenorhabdfitis elegans''<br />
**[[5gkc]], [[4qn0]] – CeENN (mutant) – ''Caenorhabdfitis elegans''<br />
**[[5gkp]] – CeENN (mutant) + DNA <br />
**[[5gkp]] – CeENN (mutant) + DNA <br />
 +
 +
*ENN Q
 +
 +
**[[7k30]], [[7k31]], [[7k32]], [[7k33]] – PfENN + DNA<br />
*ENN S
*ENN S
Line 474: Line 493:
**[[5ybb]] – ENN + R-M system + DNA – ''Caldanaerobacter subterraneus'' <br />
**[[5ybb]] – ENN + R-M system + DNA – ''Caldanaerobacter subterraneus'' <br />
-
*Apurinic-apyrimidinic ENN
+
*Apurinic-apyrimidinic ENN or APE
-
**[[5cfg]], [[6mk3]], [[6mkk]], [[6mkm]], [[6mko]] – hENN <br />
+
**[[5cfg]], [[6mk3]], [[6mkk]], [[6mkm]], [[6mko]] – hAPE1 <br />
-
**[[5dff]], [[5dfh]], [[5dfi]], [[5dfj]], [[5dg0]], [[5wn5]], [[5wn4]], [[5wn3]], [[5wn2]], [[5wn1]], [[5wn0]], [[6bos]], [[6w3l]], [[6w3n]], [[6w3q]], [[6w3u]] – hENN + DNA<br />
+
**[[5dff]], [[5dfh]], [[5dfi]], [[5dfj]], [[5dg0]], [[5wn5]], [[5wn4]], [[5wn3]], [[5wn2]], [[5wn1]], [[5wn0]], [[6bos]], [[6w3l]], [[6w3n]], [[6w3q]], [[6w3u]] – hAPE1 + DNA<br />
-
**[[6bot]], [[6boq]], [[6bor]], [[6bou]], [[6bov]], [[6bow]], [[6p93]], [[6p94]], [[6w0q]], [[6w43]], [[6w4i]], [[6w4t]] – hENN (mutant) + DNA<br />
+
**[[6bot]], [[6boq]], [[6bor]], [[6bou]], [[6bov]], [[6bow]], [[6p93]], [[6p94]], [[6w0q]], [[6w43]], [[6w4i]], [[6w4t]] – hAPE1 (mutant) + DNA<br />
 +
**[[7cd5]], [[7cd6]] – mAPE1 + DNA<br />
 +
**[[6wcd]] – fAPE2 catalytic domain - frog<br />
*Restriction ENN Pfoi
*Restriction ENN Pfoi

Revision as of 07:42, 15 July 2021

3D structures of endonuclease

Updated on 15-July-2021

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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