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2xu1
From Proteopedia
(Difference between revisions)
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<StructureSection load='2xu1' size='340' side='right'caption='[[2xu1]], [[Resolution|resolution]] 1.45Å' scene=''> | <StructureSection load='2xu1' size='340' side='right'caption='[[2xu1]], [[Resolution|resolution]] 1.45Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xu1]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2xu1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XU1 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=424:(2S,4R)-1-[1-(4-CHLOROPHENYL)CYCLOPROPYL]CARBONYL-4-(2-CHLOROPHENYL)SULFONYL-N-[1-(IMINOMETHYL)CYCLOPROPYL]PYRROLIDINE-2-CARBOXAMIDE'>424</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=424:(2S,4R)-1-[1-(4-CHLOROPHENYL)CYCLOPROPYL]CARBONYL-4-(2-CHLOROPHENYL)SULFONYL-N-[1-(IMINOMETHYL)CYCLOPROPYL]PYRROLIDINE-2-CARBOXAMIDE'>424</scene></td></tr> | ||
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1cjl|1cjl]], [[1cs8|1cs8]], [[2xu4|2xu4]], [[2vhs|2vhs]], [[1icf|1icf]], [[2xu3|2xu3]], [[1mhw|1mhw]], [[2xu5|2xu5]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1cjl|1cjl]], [[1cs8|1cs8]], [[2xu4|2xu4]], [[2vhs|2vhs]], [[1icf|1icf]], [[2xu3|2xu3]], [[1mhw|1mhw]], [[2xu5|2xu5]]</div></td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cathepsin_L Cathepsin L], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.15 3.4.22.15] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xu1 OCA], [https://pdbe.org/2xu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xu1 RCSB], [https://www.ebi.ac.uk/pdbsum/2xu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xu1 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN]] Important for the overall degradation of proteins in lysosomes. |
==See Also== | ==See Also== | ||
Revision as of 12:17, 27 April 2022
CATHEPSIN L WITH A NITRILE INHIBITOR
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