6m6k
From Proteopedia
(Difference between revisions)
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==NMR solution structure of a DNA minidumbbell containing an abasic bulge between two CCTG repeats== | ==NMR solution structure of a DNA minidumbbell containing an abasic bulge between two CCTG repeats== | ||
| - | <StructureSection load='6m6k' size='340' side='right'caption='[[6m6k]]' scene=''> | + | <StructureSection load='6m6k' size='340' side='right'caption='[[6m6k]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full | + | <table><tr><td colspan='2'>[[6m6k]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M6K OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6M6K FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6m6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m6k OCA], [http://pdbe.org/6m6k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6m6k RCSB], [http://www.ebi.ac.uk/pdbsum/6m6k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6m6k ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> |
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=3DR:1,2-DIDEOXYRIBOFURANOSE-5-PHOSPHATE'>3DR</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6m6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m6k OCA], [http://pdbe.org/6m6k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6m6k RCSB], [http://www.ebi.ac.uk/pdbsum/6m6k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6m6k ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Here we report that incorporation of an abasic site to DNA minidumbbells formed by natural sequences can lead to significant enhancements in their thermodynamic stability. Based on these stable minidumbbells, the first metal ion-controlled molecular switch which can regulate instant and reversible DNA duplex formation and dissociation has been constructed. | ||
| + | |||
| + | Rational design of a reversible Mg(2+)/EDTA-controlled molecular switch based on a DNA minidumbbell.,Wan L, Lam SL, Lee HK, Guo P Chem Commun (Camb). 2020 Sep 1;56(70):10127-10130. doi: 10.1039/d0cc03774e. PMID:32870195<ref>PMID:32870195</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 6m6k" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Guo P]] | + | [[Category: Guo, P]] |
| - | [[Category: Lam | + | [[Category: Lam, S L]] |
| - | [[Category: Wan L]] | + | [[Category: Wan, L]] |
| + | [[Category: Abasic site]] | ||
| + | [[Category: Bulge]] | ||
| + | [[Category: Cc mispair]] | ||
| + | [[Category: Dna]] | ||
| + | [[Category: Minidumbbell]] | ||
Revision as of 10:05, 16 September 2020
NMR solution structure of a DNA minidumbbell containing an abasic bulge between two CCTG repeats
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Categories: Large Structures | Guo, P | Lam, S L | Wan, L | Abasic site | Bulge | Cc mispair | Dna | Minidumbbell
