This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5m8p

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:25, 7 December 2022) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='5m8p' size='340' side='right'caption='[[5m8p]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='5m8p' size='340' side='right'caption='[[5m8p]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5m8p]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M8P OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5M8P FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5m8p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M8P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M8P FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TYR:TYROSINE'>TYR</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TYR:TYROSINE'>TYR</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TYRP1, CAS2, TYRP, TYRRP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m8p OCA], [https://pdbe.org/5m8p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m8p RCSB], [https://www.ebi.ac.uk/pdbsum/5m8p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m8p ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5m8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m8p OCA], [http://pdbe.org/5m8p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m8p RCSB], [http://www.ebi.ac.uk/pdbsum/5m8p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m8p ProSAT]</span></td></tr>
+
</table>
</table>
== Disease ==
== Disease ==
-
[[http://www.uniprot.org/uniprot/TYRP1_HUMAN TYRP1_HUMAN]] Oculocutaneous albinism type 3. The disease is caused by mutations affecting the gene represented in this entry.
+
[https://www.uniprot.org/uniprot/TYRP1_HUMAN TYRP1_HUMAN] Oculocutaneous albinism type 3. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/TYRP1_HUMAN TYRP1_HUMAN]] Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.[UniProtKB:P07147]
+
[https://www.uniprot.org/uniprot/TYRP1_HUMAN TYRP1_HUMAN] Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.[UniProtKB:P07147]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 25: Line 24:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Dijkstra, B W]]
+
[[Category: Dijkstra BW]]
-
[[Category: Lai, X]]
+
[[Category: Lai X]]
-
[[Category: Soler-Lopez, M]]
+
[[Category: Soler-Lopez M]]
-
[[Category: Wichers, H J]]
+
[[Category: Wichers HJ]]
-
[[Category: Human tyrosinase related protein 1]]
+
-
[[Category: Melanin biosynthesis]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Tyrosinase]]
+
-
[[Category: Unknown function]]
+

Current revision

Crystal structure of human tyrosinase related protein 1 in complex with tyrosine

PDB ID 5m8p

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5m8p"
Personal tools