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2z9n

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Current revision (13:27, 1 November 2023) (edit) (undo)
 
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<StructureSection load='2z9n' size='340' side='right'caption='[[2z9n]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='2z9n' size='340' side='right'caption='[[2z9n]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2z9n]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z9N OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2Z9N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2z9n]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z9N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z9N FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2r2k|2r2k]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2z9n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z9n OCA], [http://pdbe.org/2z9n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z9n RCSB], [http://www.ebi.ac.uk/pdbsum/2z9n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2z9n ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z9n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z9n OCA], [https://pdbe.org/2z9n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z9n RCSB], [https://www.ebi.ac.uk/pdbsum/2z9n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z9n ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR]] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
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[https://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Camelus dromedarius]]
[[Category: Camelus dromedarius]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Jain, R]]
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[[Category: Jain R]]
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[[Category: Kaur, P]]
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[[Category: Kaur P]]
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[[Category: Sharma, P]]
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[[Category: Sharma P]]
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[[Category: Sharma, S]]
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[[Category: Sharma S]]
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[[Category: Singh, N]]
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[[Category: Singh N]]
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[[Category: Singh, T P]]
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[[Category: Singh TP]]
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[[Category: Antibiotic]]
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[[Category: Antimicrobial]]
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[[Category: Complex]]
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[[Category: Crystal]]
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[[Category: Immune response]]
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[[Category: Immune system]]
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[[Category: Peptidoglycan recognition protein]]
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[[Category: Secreted]]
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Current revision

Crystal structure of cameline peptidoglycan recognition protein at 3.2 A resolution

PDB ID 2z9n

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