3a8b

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<StructureSection load='3a8b' size='340' side='right'caption='[[3a8b]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='3a8b' size='340' side='right'caption='[[3a8b]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3a8b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A8B OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3A8B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3a8b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A8B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A8B FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR6:(E)-4-((4-BROMOPHENYLIMINO)METHYL)BENZIMIDAMIDE'>BR6</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3a7t|3a7t]], [[3a7v|3a7v]], [[3a7w|3a7w]], [[3a7x|3a7x]], [[3a7y|3a7y]], [[3a7z|3a7z]], [[3a80|3a80]], [[3a81|3a81]], [[3a82|3a82]], [[3a83|3a83]], [[3a84|3a84]], [[3a85|3a85]], [[3a86|3a86]], [[3a87|3a87]], [[3a88|3a88]], [[3a89|3a89]], [[3a8a|3a8a]], [[3a8c|3a8c]], [[3a8d|3a8d]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR6:(E)-4-((4-BROMOPHENYLIMINO)METHYL)BENZIMIDAMIDE'>BR6</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a8b OCA], [https://pdbe.org/3a8b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a8b RCSB], [https://www.ebi.ac.uk/pdbsum/3a8b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a8b ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3a8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a8b OCA], [http://pdbe.org/3a8b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a8b RCSB], [http://www.ebi.ac.uk/pdbsum/3a8b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3a8b ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Trypsin]]
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[[Category: Tanaka I]]
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[[Category: Tanaka, I]]
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[[Category: Yamane J]]
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[[Category: Yamane, J]]
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[[Category: Yao M]]
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[[Category: Yao, M]]
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[[Category: Disulfide bond]]
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[[Category: Hydrolase]]
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[[Category: In-crystal chemical ligation]]
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[[Category: Metal-binding]]
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[[Category: Protease]]
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[[Category: Secreted]]
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[[Category: Serine protease]]
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[[Category: Zymogen]]
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Revision as of 14:15, 1 November 2023

Crystal Structure of Trypsin complexed with (E)-4-((4-bromophenylimino)methyl)benzimidamide

PDB ID 3a8b

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