2jis
From Proteopedia
(Difference between revisions)
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<StructureSection load='2jis' size='340' side='right'caption='[[2jis]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='2jis' size='340' side='right'caption='[[2jis]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2jis]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2jis]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JIS FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jis OCA], [https://pdbe.org/2jis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jis RCSB], [https://www.ebi.ac.uk/pdbsum/2jis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jis ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CSAD_HUMAN CSAD_HUMAN] Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. The preferred substrate is 3-sulfino-L-alanine. Does not exhibit any decarboxylation activity toward glutamate.[UniProtKB:Q9DBE0] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/2jis_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/2jis_consurf.spt"</scriptWhenChecked> | ||
| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Arrowsmith C]] | |
| - | [[Category: Arrowsmith | + | [[Category: Berglund H]] |
| - | + | [[Category: Busam R]] | |
| - | [[Category: Berglund | + | [[Category: Collins R]] |
| - | [[Category: Busam | + | [[Category: Dahlgren LG]] |
| - | [[Category: Collins | + | [[Category: Edwards A]] |
| - | [[Category: Dahlgren | + | [[Category: Flodin S]] |
| - | [[Category: Edwards | + | [[Category: Flores A]] |
| - | [[Category: Flodin | + | [[Category: Graslund S]] |
| - | [[Category: Flores | + | [[Category: Hallberg BM]] |
| - | [[Category: Graslund | + | [[Category: Hammarstrom M]] |
| - | [[Category: Hallberg | + | [[Category: Holmberg-Schiavone L]] |
| - | [[Category: Hammarstrom | + | [[Category: Johansson I]] |
| - | [[Category: Holmberg-Schiavone | + | [[Category: Kallas A]] |
| - | [[Category: Johansson | + | [[Category: Karlberg T]] |
| - | [[Category: Kallas | + | [[Category: Kotenyova T]] |
| - | [[Category: Karlberg | + | [[Category: Lehtio L]] |
| - | [[Category: Kotenyova | + | [[Category: Moche M]] |
| - | [[Category: Lehtio | + | [[Category: Nordlund P]] |
| - | [[Category: Moche | + | [[Category: Nyman T]] |
| - | [[Category: Nordlund | + | [[Category: Ogg D]] |
| - | [[Category: Nyman | + | [[Category: Persson C]] |
| - | [[Category: Ogg | + | [[Category: Sagemark J]] |
| - | [[Category: Persson | + | [[Category: Stenmark P]] |
| - | + | [[Category: Sundstrom M]] | |
| - | [[Category: Sagemark | + | [[Category: Thorsell AG]] |
| - | [[Category: Stenmark | + | [[Category: Tresaugues L]] |
| - | [[Category: Sundstrom | + | [[Category: Weigelt J]] |
| - | [[Category: Thorsell | + | [[Category: Welin M]] |
| - | [[Category: Tresaugues | + | [[Category: Van den Berg S]] |
| - | [[Category: Weigelt | + | |
| - | [[Category: Welin | + | |
| - | [[Category: | + | |
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Current revision
Human cysteine sulfinic acid decarboxylase (CSAD) in complex with PLP.
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Categories: Homo sapiens | Large Structures | Arrowsmith C | Berglund H | Busam R | Collins R | Dahlgren LG | Edwards A | Flodin S | Flores A | Graslund S | Hallberg BM | Hammarstrom M | Holmberg-Schiavone L | Johansson I | Kallas A | Karlberg T | Kotenyova T | Lehtio L | Moche M | Nordlund P | Nyman T | Ogg D | Persson C | Sagemark J | Stenmark P | Sundstrom M | Thorsell AG | Tresaugues L | Weigelt J | Welin M | Van den Berg S
