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5k4u

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Current revision (10:39, 27 September 2023) (edit) (undo)
 
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<StructureSection load='5k4u' size='340' side='right'caption='[[5k4u]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='5k4u' size='340' side='right'caption='[[5k4u]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5k4u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_(trypanozoon)_brucei Trypanosoma (trypanozoon) brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K4U OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5K4U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5k4u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K4U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5K4U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-threonine_3-dehydrogenase L-threonine 3-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.103 1.1.1.103] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5k4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k4u OCA], [http://pdbe.org/5k4u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k4u RCSB], [http://www.ebi.ac.uk/pdbsum/5k4u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k4u ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k4u OCA], [https://pdbe.org/5k4u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k4u RCSB], [https://www.ebi.ac.uk/pdbsum/5k4u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k4u ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q7YW97_9TRYP Q7YW97_9TRYP]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: L-threonine 3-dehydrogenase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Adjogatse, E K]]
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[[Category: Trypanosoma brucei]]
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[[Category: Cooper, J B]]
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[[Category: Adjogatse EK]]
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[[Category: Erskine, P T]]
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[[Category: Cooper JB]]
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[[Category: Holo]]
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[[Category: Erskine PT]]
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[[Category: Ligand-bound]]
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[[Category: Oxidoreductase]]
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[[Category: Short-chain dehydrogenase]]
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Current revision

Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei showing different active site loop conformations between dimer subunits, refined to 1.9 angstroms

PDB ID 5k4u

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