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5l0k

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Current revision (16:04, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5l0k' size='340' side='right'caption='[[5l0k]], [[Resolution|resolution]] 2.73&Aring;' scene=''>
<StructureSection load='5l0k' size='340' side='right'caption='[[5l0k]], [[Resolution|resolution]] 2.73&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5l0k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L0K OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5L0K FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5l0k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L0K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L0K FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6ZO:(3,5-DICHLOROPHENYL)METHYL+4-[3-OXO-3-(2-OXO-2,3-DIHYDRO-1,3-BENZOXAZOL-6-YL)PROPYL]PIPERAZINE-1-CARBOXYLATE'>6ZO</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.73&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5l0b|5l0b]], [[5l0e|5l0e]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6ZO:(3,5-DICHLOROPHENYL)METHYL+4-[3-OXO-3-(2-OXO-2,3-DIHYDRO-1,3-BENZOXAZOL-6-YL)PROPYL]PIPERAZINE-1-CARBOXYLATE'>6ZO</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Enpp2, Atx, Npps2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l0k OCA], [https://pdbe.org/5l0k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l0k RCSB], [https://www.ebi.ac.uk/pdbsum/5l0k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l0k ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alkylglycerophosphoethanolamine_phosphodiesterase Alkylglycerophosphoethanolamine phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.39 3.1.4.39] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5l0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l0k OCA], [http://pdbe.org/5l0k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l0k RCSB], [http://www.ebi.ac.uk/pdbsum/5l0k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l0k ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ENPP2_RAT ENPP2_RAT]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Alkylglycerophosphoethanolamine phosphodiesterase]]
 
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[[Category: Buffalo rat]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Durbin, J D]]
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[[Category: Rattus norvegicus]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Durbin JD]]
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[[Category: Phospholipase]]
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Current revision

Crystal Structure of Autotaxin and Compound PF-8380

PDB ID 5l0k

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