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5l8p

From Proteopedia

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Current revision (16:11, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5l8p' size='340' side='right'caption='[[5l8p]], [[Resolution|resolution]] 1.29&Aring;' scene=''>
<StructureSection load='5l8p' size='340' side='right'caption='[[5l8p]], [[Resolution|resolution]] 1.29&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5l8p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L8P OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5L8P FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5l8p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L8P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L8P FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6MG:N~2~-[(R)-({[(BENZYLOXY)CARBONYL]AMINO}METHYL)(HYDROXY)PHOSPHORYL]-N-[(2S)-2,3,3-TRIMETHYLBUTYL]-L-LEUCINAMIDE'>6MG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.29&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6MG:N~2~-[(R)-({[(BENZYLOXY)CARBONYL]AMINO}METHYL)(HYDROXY)PHOSPHORYL]-N-[(2S)-2,3,3-TRIMETHYLBUTYL]-L-LEUCINAMIDE'>6MG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5l8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l8p OCA], [http://pdbe.org/5l8p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l8p RCSB], [http://www.ebi.ac.uk/pdbsum/5l8p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l8p ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l8p OCA], [https://pdbe.org/5l8p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l8p RCSB], [https://www.ebi.ac.uk/pdbsum/5l8p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l8p ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/THER_BACTH THER_BACTH]] Extracellular zinc metalloprotease.
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[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5l8p" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5l8p" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Thermolysin 3D structures|Thermolysin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Thermolysin]]
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[[Category: Cramer J]]
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[[Category: Cramer, J]]
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[[Category: Heine A]]
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[[Category: Heine, A]]
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[[Category: Klebe G]]
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[[Category: Klebe, G]]
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[[Category: Krimmer SG]]
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[[Category: Krimmer, S G]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase inhibitor complex]]
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[[Category: Metalloprotease]]
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Current revision

Thermolysin in complex with JC114 (PEG400 cryo protectant)

PDB ID 5l8p

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