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Antibody 3D structures

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Line 11: Line 11:
*Fab
*Fab
-
**[[7fab]], [[1mco]], [[3na9]], [[3lrs]], [[3mme]], [[3hi5]], [[1vge]], [[3nfs]], [[1ad0]], [[3w9d]], [[4nm4]], [[8fab]], [[1opg]], [[4fnl]], [[4fqh]], [[6n32]], [[1aqk]], [[2hff]], [[2agj]], [[3hc0]], [[3g6a]], [[3dgg]], [[3dif]], [[1b2w]], [[3eyo]], [[3eyq]], [[2aj3]], [[3fzu]], [[3aaz]], [[3gje]], [[5fhb]], [[5fha]], [[5f6i]], [[5f6h]], [[5drw]], [[5d6c]], [[4py7]], [[4ptt]], [[4ob5]], [[5szf]], [[5chn]], [[4lkc]], [[4hie]], [[4gxv]], [[6u85]] - hFab - human<br />
+
**[[7fab]], [[1mco]], [[3na9]], [[3lrs]], [[3mme]], [[3hi5]], [[1vge]], [[3nfs]], [[1ad0]], [[3w9d]], [[4nm4]], [[8fab]], [[1opg]], [[4fnl]], [[4fqh]], [[6n32]], [[1aqk]], [[2hff]], [[2agj]], [[3hc0]], [[3g6a]], [[3dgg]], [[3dif]], [[1b2w]], [[3eyo]], [[3eyq]], [[2aj3]], [[3fzu]], [[3aaz]], [[3gje]], [[5fhb]], [[5fha]], [[5f6i]], [[5f6h]], [[5drw]], [[5d6c]], [[4py7]], [[4ptt]], [[4ob5]], [[5szf]], [[5chn]], [[4lkc]], [[4hie]], [[4gxv]], [[6be2]], [[6be4]], [[6cbj]], [[6dcv]], [[6dwc]], [[6foe]], [[6ghg]], [[6hkg]], [[6ias]], [[6nuy]], [[6nuz]], [[6nv0]], [[6obz]], [[6pzg]], [[6pzh]], [[6q19]], [[6q1a]], [[6q1e]], [[6q1g]], [[6q1j]], [[6q1k]], [[6qbc]], [[6qcu]], [[6srv]], [[6srx]], [[6ss0]], [[6tul]], [[6u85]], [[6u9u]], [[6vi2]], [[6vrq]], [[6v4r]], [[6vpy]], [[6vtu]], [[6w5a]], [[6w5d]], [[6wiy]], [[6wj0]], [[6wla]], [[6x9x]], [[6xrj]], [[6z3k]] - hFab - human<br />
-
**[[3naa]], [[3nab]], [[3nac]], [[3ncj]], [[3o2v]], [[3hc3]], [[3hc4]] - hFab (mutant)<br />
+
**[[3naa]], [[3nab]], [[3nac]], [[3ncj]], [[3o2v]], [[3hc3]], [[3hc4]], [[6uum]], [[6y1k]], [[6y1l]], [[6y1m]], [[6y1n]] - hFab (mutant)<br />
**[[6b0w]], [[6azx]], [[5bk5]], [[5bk3]] - hFab anti-circumsporozoite<br />
**[[6b0w]], [[6azx]], [[5bk5]], [[5bk3]] - hFab anti-circumsporozoite<br />
-
**[[6meg]], [[6med]], [[6mee]], [[6mef]] - hFab anti-hepacivirus<br />
+
**[[6b6z]], [[6dzn]], [[5vz1]] - hFab anti-ebola virus<br />
-
**[[6dzn]], [[5vz1]] - hFab anti-ebola virus<br />
+
**[[6mtx]], [[6mty]], [[6nis]] - hFab anti-zika virus<br />
-
**[[6nis]] - hFab anti-zika virus<br />
+
**[[6ws6]] - hFab anti-sarbecovirus<br />
**[[6phg]], [[6phh]] - hFab anti-malaria<br />
**[[6phg]], [[6phh]] - hFab anti-malaria<br />
-
**[[3i75]], [[1nqb]], [[1f4w]], [[1aif]], [[1ghf]], [[2z91]], [[1ind]], [[3bkc]], [[3bkm]], [[1iy0]], [[3pp3]], [[3pp4]], [[3okm]], [[6fab]], [[2hkh]], [[1ay1]], [[1nbv]], [[1qbm]], [[1bbd]], [[1dsf]], [[1gpo]], [[1mnu]], [[1igf]], [[1for]], [[1k6q]], [[1bz7]], [[1dqd]], [[2ipt]], [[2iq9]], [[2iqa]], [[2w60]], [[2w9d]], [[3iu4]], [[1q9k]], [[1q9l]], [[1q9o]], [[2z4q]], [[1cl7]], [[1cr9]], [[1r24]], [[1gig]], [[1uyw]], [[1cgs]], [[2cgr]], [[1q0x]], [[1ibg]], [[3eo0]], [[2op4]], [[2q76]], [[2ojz]], [[2g60]], [[2dbl]], [[1dbj]], [[1dbk]], [[1dbm]], [[1dba]], [[1mrc]], [[2gcy]], [[1flr]], [[1uz6]], [[1rfd]], [[1t2q]], [[1ggb]], [[1ggc]], [[1bm3]], [[2eh7]], [[2fat]], [[3cfc]], [[1fl3]], [[3cfe]], [[4j1u]], [[4gq9]], [[3qg7]], [[3rvt]], [[3s62]], [[4gay]], [[5mx3]], [[5l88]], [[5i66]], [[5cma]], [[5az2]], [[4z0b]], [[4qth]], [[4poz]], [[5vzr]], [[5lgh]], [[5l9d]], [[5l7x]], [[5h2b]], [[4lci]], [[4k23]], [[6p79]] - mFab – mouse<br />
+
**[[6dl8]] - hFab anti-influenza<br />
 +
**[[6nb5]] - hFab anti-MERS-CoV<br />
 +
**[[3i75]], [[1nqb]], [[1f4w]], [[1aif]], [[1ghf]], [[2z91]], [[1ind]], [[3bkc]], [[3bkm]], [[1iy0]], [[3pp3]], [[3pp4]], [[3okm]], [[6fab]], [[2hkh]], [[1ay1]], [[1nbv]], [[1qbm]], [[1bbd]], [[1dsf]], [[1gpo]], [[1mnu]], [[1igf]], [[1for]], [[1k6q]], [[1bz7]], [[1dqd]], [[2ipt]], [[2iq9]], [[2iqa]], [[2w60]], [[2w9d]], [[3iu4]], [[1q9k]], [[1q9l]], [[1q9o]], [[2z4q]], [[1cl7]], [[1cr9]], [[1r24]], [[1gig]], [[1uyw]], [[1cgs]], [[2cgr]], [[1q0x]], [[1ibg]], [[3eo0]], [[2op4]], [[2q76]], [[2ojz]], [[2g60]], [[2dbl]], [[1dbj]], [[1dbk]], [[1dbm]], [[1dba]], [[1mrc]], [[2gcy]], [[1flr]], [[1uz6]], [[1rfd]], [[1t2q]], [[1ggb]], [[1ggc]], [[1bm3]], [[2eh7]], [[2fat]], [[3cfc]], [[1fl3]], [[3cfe]], [[4j1u]], [[4gq9]], [[3qg7]], [[3rvt]], [[3s62]], [[4gay]], [[5mx3]], [[5l88]], [[5i66]], [[5cma]], [[5az2]], [[4z0b]], [[4qth]], [[4poz]], [[5vzr]], [[5lgh]], [[5l9d]], [[5l7x]], [[5h2b]], [[4lci]], [[4k23]], [[6hgu]], [[6ks2]], [[6kx0]], [[6p4y]], [[6p79]], [[6qnk]], [[6shg]], [[6ug7]], [[6ug8]], [[6uga]], [[6ugd]], [[6vl8]], [[6vl9]], [[6w4v]], [[6x5e]], [[6xuk]], [[6y54]], [[6z7x]], [[7c95]] - mFab – mouse<br />
**[[3eot]], [[2d03]], [[3esv]], [[3et9]] – mFab (mutant)<br />
**[[3eot]], [[2d03]], [[3esv]], [[3et9]] – mFab (mutant)<br />
**[[3iy2]], [[3iy3]], [[3iy4]], [[3iy5]], [[3iy6]], [[3iy7]] - mFab – Cryo EM<br />
**[[3iy2]], [[3iy3]], [[3iy4]], [[3iy5]], [[3iy6]], [[3iy7]] - mFab – Cryo EM<br />
-
**[[1jpt]], [[3mxv]], [[2o5x]], [[1ucb]], [[1bbj]], [[1t04]], [[2fgw]], [[1fvd]], [[1fve]], [[4kuz]], [[6l8t]] - hmFab <br />
+
**[[1jpt]], [[3mxv]], [[2o5x]], [[1ucb]], [[1bbj]], [[1t04]], [[2fgw]], [[1fvd]], [[1fve]], [[4kuz]], [[6l8t]], [[6w4w]] - hmFab <br />
**[[1cqk]] – mFab MAK33 CH3 domain<br />
**[[1cqk]] – mFab MAK33 CH3 domain<br />
**[[6a0x]] - mFab anti-influenza virus<br />
**[[6a0x]] - mFab anti-influenza virus<br />
 +
**[[6u1t]] - mFab anti-Nipa virus<br />
**[[6h3h]] - mFab anti-fullerene<br />
**[[6h3h]] - mFab anti-fullerene<br />
**[[6pyc]] - mFab anti-kappa<br />
**[[6pyc]] - mFab anti-kappa<br />
**[[6pyd]] - mFab anti-marinobufagenin<br />
**[[6pyd]] - mFab anti-marinobufagenin<br />
**[[6idh]], [[6kdh]] - mFab anti-photoproduct<br />
**[[6idh]], [[6kdh]] - mFab anti-photoproduct<br />
 +
**[[6pxg]] - mFab anti-MERS-CoV<br />
 +
**[[6gxx]], [[6i1o]], [[6qu9]] - mFab anti-antitrypsin<br />
**[[3mj8]], [[3r06]] – AhFab – Armenian hamster<br />
**[[3mj8]], [[3r06]] – AhFab – Armenian hamster<br />
-
**[[3iy1]], [[1zan]] – raFab – rat<br />
+
**[[3iy1]], [[1zan]], [[6e64]] – raFab – rat<br />
-
**[[4k3e]], [[4k3d]] – bFab – bovine<br />
+
**[[4k3e]], [[4k3d]], [[6oo0]], [[6qn7]], [[6qn8]], [[6qn9]], [[6qna]] – bFab – bovine<br />
**[[6e8v]] – bFab-1<br />
**[[6e8v]] – bFab-1<br />
**[[6e9g]] – bFab-2<br />
**[[6e9g]] – bFab-2<br />
Line 39: Line 44:
**[[6e9u]] – bFab-7<br />
**[[6e9u]] – bFab-7<br />
**[[4b41]], [[4m3j]] – LgFab – ''Lama glama''<br />
**[[4b41]], [[4m3j]] – LgFab – ''Lama glama''<br />
 +
**[[6cjk]] – rFab - rabbit<br />
**[[6df0]], [[6dez]] - syFab anti-phosphotyrosine - synthetic<br />
**[[6df0]], [[6dez]] - syFab anti-phosphotyrosine - synthetic<br />
Line 44: Line 50:
*Anti-HIV Fab
*Anti-HIV Fab
-
**[[1rz7]], [[1rz8]], [[1rzf]], [[1rzg]], [[1rzi]], [[3mlj]], [[3mug]], [[3qeh]], [[3ttn]], [[rpi]], [[3tnm]], [[4fz8]], [[4f58]], [[4f57]], [[4f5a]], [[5iie]], [[5dt1]], [[5cey]], [[5cex]], [[5cck]], [[5bzw]], [[5bzd]], [[4rqq]], [[5uy3]], [[4qf1]], [[6mtr]], [[6mts]] - hFab <br />
+
**[[1rz7]], [[1rz8]], [[1rzf]], [[1rzg]], [[1rzi]], [[3mlj]], [[3mug]], [[3qeh]], [[3ttn]], [[rpi]], [[3tnm]], [[4fz8]], [[4f58]], [[4f57]], [[4f5a]], [[5iie]], [[5dt1]], [[5cey]], [[5cex]], [[5cck]], [[5bzw]], [[5bzd]], [[4rqq]], [[5uy3]], [[4qf1]], [[6avn]], [[6b3d]], [[6bla]], [[6cxl]], [[6mtr]], [[6mts]], [[6o3d]], [[6o3k]], [[6uul]], [[6vu2]], [[6wor]], [[6wos]] - hFab <br />
**[[3nz8]], [[3o6k]], [[3ntc]], [[3qeg]] – mFab <br />
**[[3nz8]], [[3o6k]], [[3ntc]], [[3qeg]] – mFab <br />
**[[5kg9]] – hmFab <br />
**[[5kg9]] – hmFab <br />
-
**[[5dd6]], [[5dd5]], [[5dd3]], [[5dd1]], [[4rfe]], [[4q2z]], [[5t4z]] – rmFab – rhesus macaque <br />
+
**[[5dd6]], [[5dd5]], [[5dd3]], [[5dd1]], [[4rfe]], [[4q2z]], [[5t4z]], [[6u3z]], [[6u6m]], [[6u6o]], [[6vor]], [[6vsr]] – rmFab – rhesus macaque <br />
 +
**[[7l6m]] – rmFab – Cryo EM <br />
 +
*Anti-SARS-CoV-2 Fab
 +
 +
**[[6nb8]], [[6w7y]], [[6xca]], [[7jmx]], [[7k8n]], [[7k8o]], [[7k8q]], [[7k8r]], [[7kza]], [[7kzc]], [[7lk9]], [[7lka]] - hFab anti-SARS-CoV-2<br />
 +
**[[6c6z]], [[4xak]], [[6w41]], [[6xc2]], [[6xc3]], [[6xc4]], [[6xc7]], [[6xe1]], [[6xkp]], [[6xkq]], [[6yla]], [[6ym0]], [[6zer]], [[6zlr]], [[7bei]], [[7bem]], [[7bwj]], [[7bz5]], [[7c01]], [[7chb]], [[7chc]], [[7che]], [[7chf]], [[7cm4]], [[7jmw]], [[7jn5]], [[7k8m]], [[7k8v]], [[7k8w]], [[7kfv]], [[7kfw]], [[7kfx]], [[7kfy]], [[7klg]], [[7klh]], [[7kmg]], [[7kmh]], [[7kmi]], [[7kzb]], [[7l2c]], [[7lop]], [[7neg]] - hFab + SARS-CoV-2 spike protein <br />
 +
**[[6nb6]], [[6nb7]], [[6wps]], [[6wpt]], [[6xcm]], [[6xcn]], [[6xdg]], [[6xey]], [[6yor]], [[6zdh]], [[6zdg]], [[6zfo]], [[7a5r]], [[7a5s]], [[7byr]], [[7cac]], [[7cai]], [[7cak]], [[7bwj]], [[7c2l]], [[7cah]], [[7chh]], [[7cwl]], [[7cwm]], [[7cwn]], [[7cwo]], [[7cws]], [[7cwu]], [[7czq]], [[7czr]], [[7czs]], [[7czt]], [[7czu]], [[7czv]], [[7czw]], [[7czp]], [[7czx]], [[7d03]], [[7d0b]], [[7d0c]], [[7d0d]], [[7jv2]], [[7jv4]], [[7jv6]], [[7jva]], [[7jvc]], [[7jw0]], [[7k43]], [[7k45]], [[7k4n]], [[7k8t]], [[7k8u]], [[7k8x]], [[7k8y]], [[7k8z]], [[7k8s]], [[7k90]], [[7kmk]], [[7kml]], [[7l02]], [[7l06]], [[7l09]], [[7l2e]], [[7l3n]], [[7laa]], [[7lab]], [[7ld1]], [[7lcn]], [[7ljr]], [[7lm8]], [[7lqv]],[[7lqw]], [[7ls9]], [[7lss]], [[7nd4]], [[7nda]] - hFab + SARS-CoV-2 spike protein – Cryo EM<br />
 +
**[[7b3o]] - hFab + SARS-CoV-2 surface glycoprotein <br />
 +
**[[6yz7]], [[6z2m]], [[6zcz]], [[6zh9]] - hFab + SARS-CoV-2 spike protein + nanobody<br />
 +
**[[7kn6]], [[7kn7]] - hFab + ViVHH + SARS-CoV-2 spike protein<br />
 +
**[[7kkj]] – syVHH anti-SARS<br />
 +
**[[6waq]], [[6z43]] – LgVHH anti-SARS + spike protein<br />
 +
**[[7kn5]] – ViVHH anti-SARS + spike protein <br />
 +
**[[6zxn]] – ViVHH anti-SARS + spike protein – Cryo EM<br />
 +
**[[7c8v]], [[7c8w]], [[7can]], [[7d2z]], [[7d30]], [[7kgj]], [[7kgk]], [[7klw]] – syVHH + SARS-CoV-2 spike protein<br/>
 +
**[[7a25]], [[7a29]], [[7kkk]], [[7kkl]] – syVHH + SARS-CoV-2 spike protein – Cryo EM<br/>
 +
**[[7ean]] - mFab + SARS-CoV-2 spike protein <br />
 +
 +
*Anti-hepatitis Fab
 +
 +
**[[6mwn]] – hFab + hepatitis A virus RNA<br />
 +
**[[6jhq]], [[6jhr]], [[6jhs]], [[6jht]] - mFab + hepatitis A proteins – Cryo EM<br />
 +
**[[6txz]] – sFab + Hepatitis A virus protein<br />
 +
**[[6cwt]] – rFab + Hepatitis B capsid<br />
 +
**[[6cwd]] – rscFv + hepatitis B capsid<br />
 +
**[[6meg]], [[6med]], [[6mee]], [[6mef]], [[6wo5]] - hFab anti-hepatitis C virus<br />
 +
**[[5nph]], [[6bzu]], [[6bzv]], [[6bzw]], [[6bzy]] – mFab + hepatitis C virus peptide <br />
 +
**[[4hs8]], [[5kzp]] – hFab + hepatitis C virus peptide <br />
 +
**[[4why]], [[4wht]] - raFab + hepatitis C peptide<br />
 +
**[[6bkb]], [[6bkc]], [[6bkd]], [[6mej]], [[6meh]], [[6mei]], [[6mek]], [[6u8d]], [[6u8k]], [[6uyf]], [[6urh]], [[6uyd]], [[6uyg]], [[6uym]], [[6wo3]], [[6wo4]], [[6woq]] - hFab anti-hepatitis C virus + glycoprotein<br />
 +
**[[7jtf]], [[7jtg]] - rmFab + hepatitis C envelope protein<br />
 +
**[[5npi]], [[5npj]] – mscFv + hepatitis C peptide<br />
*Human Fab: small molecule complex
*Human Fab: small molecule complex
Line 58: Line 95:
**[[3oay]], [[3oaz]], [[3ob0]], [[6msy]], [[6mub]], [[6mu3]], [[6mnf]] - hFab 2g12 + glycan<br />
**[[3oay]], [[3oaz]], [[3ob0]], [[6msy]], [[6mub]], [[6mu3]], [[6mnf]] - hFab 2g12 + glycan<br />
**[[6n35]], [[6n2x]], [[5i8o]] - hFab + polysaccharide<br />
**[[6n35]], [[6n2x]], [[5i8o]] - hFab + polysaccharide<br />
-
 
+
**[[7dc7]] - hFab + ATP<br />
 +
**[[6bjz]] - hFab + fluorescent amino acid<br />
 +
**[[6o3u]] - hFab anti-HIV + PA<br />
*Mouse Fab: small molecule complex
*Mouse Fab: small molecule complex
Line 84: Line 123:
**[[4kze]], [[4kzd]] – mFab + RNA <br />
**[[4kze]], [[4kzd]] – mFab + RNA <br />
**[[6kdi]] - mFab anti-photoproduct + DNA<br />
**[[6kdi]] - mFab anti-photoproduct + DNA<br />
- 
*Other Fab: small molecule complex
*Other Fab: small molecule complex
Line 90: Line 128:
**[[2jb5]], [[2jb6]] - hmFab + hapten<br />
**[[2jb5]], [[2jb6]] - hmFab + hapten<br />
**[[3eyv]] - hmFab 13G5 (mutant) + hapten<br />
**[[3eyv]] - hmFab 13G5 (mutant) + hapten<br />
- 
*Mouse Fab: peptide complex
*Mouse Fab: peptide complex
Line 110: Line 147:
**[[1fpt]] – mFab + poliovirus peptide<br />
**[[1fpt]] – mFab + poliovirus peptide<br />
**[[1jp5]] – mFab + HIV-1 protease peptide<br />
**[[1jp5]] – mFab + HIV-1 protease peptide<br />
 +
**[[6p8d]], [[6p8n]], [[6pdr]], [[6wwc]], [[6wx2]] – mFab + HIV-1 fusion peptide<br />
**[[1mvu]] – mFab + glycoprotein <br />
**[[1mvu]] – mFab + glycoprotein <br />
**[[2ap2]] – mFab + glycoprotein peptide + C-myc peptide<br />
**[[2ap2]] – mFab + glycoprotein peptide + C-myc peptide<br />
Line 116: Line 154:
**[[5epm]] – mFab + therapotoxin peptide<br />
**[[5epm]] – mFab + therapotoxin peptide<br />
**[[5eor]], [[5eoq]] – mFab + protein A27 peptide<br />
**[[5eor]], [[5eoq]] – mFab + protein A27 peptide<br />
-
**[[1i8i]], [[1i8k]] – mFab + EGFR peptide<br />
 
-
**[[1i8k]] – mFab + EGFR peptide<br />
 
**[[1i8i]], [[1i8k]] – mFab + EGFR peptide<br />
**[[1i8i]], [[1i8k]] – mFab + EGFR peptide<br />
**[[1i8k]] – mFab + EGFR peptide<br />
**[[1i8k]] – mFab + EGFR peptide<br />
**[[4gag]], [[4gaj]] – mFab + genome polyprotein peptide<br />
**[[4gag]], [[4gaj]] – mFab + genome polyprotein peptide<br />
-
**[[5nph]] – mFab + hepatitis virus peptide <br />
 
**[[5mv4]], [[5mu0]] – mFab + collagen peptide <br />
**[[5mv4]], [[5mu0]] – mFab + collagen peptide <br />
-
 
+
**[[6uud]], [[6x8p]], [[6x8q]], [[6x8s]], [[6x8u]] – mFab + CSP peptide<br />
 +
**[[6f7t]] – mFab + RNase peptide<br />
*Human Fab: peptide complex
*Human Fab: peptide complex
Line 134: Line 170:
**[[2hfg]], [[2h9g]] – hFab + TNF receptor peptide<br />
**[[2hfg]], [[2h9g]] – hFab + TNF receptor peptide<br />
**[[3csy]], [[6n7j]] - hFab + Ebola envelope glycoprotein peptide<br />
**[[3csy]], [[6n7j]] - hFab + Ebola envelope glycoprotein peptide<br />
-
**[[4hs8]], [[5kzp]] – hFab + hepatitis virus peptide <br />
 
**[[6b0s]], [[6azm]], [[5bk0]], [[6d11]], [[6d0x]], [[6d01]] - hFab anti-circumsporozoite + circumsporozoite domain<br />
**[[6b0s]], [[6azm]], [[5bk0]], [[6d11]], [[6d0x]], [[6d01]] - hFab anti-circumsporozoite + circumsporozoite domain<br />
-
**[[6h06]], [[6h0e]], [[6gk7]], [[6gk8]], [[5zia]], [[5zv3]] - hFab + Tau peptide<br />
+
**[[6h06]], [[6h0e]], [[6gk7]], [[6gk8]], [[5zia]], [[5zv3]], [[6dcw]], [[6lra]] - hFab + Tau peptide<br />
-
**[[6mtp]], [[6mtt]] - hFab + HIV peptide<br />
+
**[[6fy0]], [[6mtp]], [[6mtt]], [[6o3j]] - hFab + HIV peptide<br />
-
 
+
**[[6ubi]], [[6uce]], [[6ucf]], [[6pdu]] – hFab + HIV-1 fusion peptide<br />
 +
**[[6axk]], [[6axl]], [[6b5l]], [[6b5m]], [[6b5n]], [[6b5o]], [[6b5p]], [[6b5r]], [[6b5s]], [[6b5t]], [[6o23]], [[6o26]], [[6pbw]], [[6uc5]], [[6w05]], [[6wfx]], [[6wfy]], [[6wfz]], [[6wg0]], [[6wg1]], [[6wg2]] – hFab + CSP peptide<br />
 +
**[[6bqb]], [[6ct7]], [[6kva]], [[6kvf]], [[6ldv]], [[6ldw]], [[6ldx]], [[7c94]] – hFab + peptide<br />
 +
**[[6e4y]], [[6e4z]], [[6mv5]] - hFab + PCSK9 peptide<br />
*Other Fab: peptide complex
*Other Fab: peptide complex
Line 144: Line 182:
**[[2hh0]] – hmFab + prion protein peptide<br />
**[[2hh0]] – hmFab + prion protein peptide<br />
**[[3bky]] – hmFab + CD20 peptide<br />
**[[3bky]] – hmFab + CD20 peptide<br />
-
**[[5dmg]] – rFab + microtubule-associated protein peptide - rabbit<br />
+
**[[5dmg]] – rFab + microtubule-associated protein peptide<br />
 +
**[[6ldy]], [[6x1s]], [[6x1t]], [[6x1u]], [[6x1v]], [[6x1w]] – rFab + peptide<br />
**[[5dd0]] – rmFab + peptide<br />
**[[5dd0]] – rmFab + peptide<br />
-
**[[4why]], [[4wht]] - raFab + hepatitis peptide<br />
+
**[[6mnq]], [[6mnr]], [[6mns]] - rmFab anti-HIV + gp120 peptide<br />
**[[6df1]], [[6df2]] - syFab anti-phosphotyrosine + phosphotyrosine peptide<br />
**[[6df1]], [[6df2]] - syFab anti-phosphotyrosine + phosphotyrosine peptide<br />
- 
*Anti-HIV Fab: peptide complex
*Anti-HIV Fab: peptide complex
-
**[[3egs]], [[3drt]], [[3drq]], [[3dro]], [[2fx7]], [[2fx8]], [[2fx9]], [[2cmr]], [[1tzg]], [[1tjg]], [[3mnw]], [[3moa]], [[3mob]], [[3mod]], [[1tjh]], [[1tji]], [[1u8h]], [[1u8i]], [[1u8j]], [[1u8k]], [[1u8l]], [[1u8m]], [[1u8n]], [[1u8o]], [[1u8p]], [[1u8q]], [[1u91]], [[1u92]], [[1u93]], [[1u95]], [[2f5b]], [[3go1]], [[5drz]], [[4ydv]] - hFab anti-HIV + gp41 peptide<br />
+
**[[3egs]], [[3drt]], [[3drq]], [[3dro]], [[2fx7]], [[2fx8]], [[2fx9]], [[2cmr]], [[1tzg]], [[1tjg]], [[3mnw]], [[3moa]], [[3mob]], [[3mod]], [[1tjh]], [[1tji]], [[1u8h]], [[1u8i]], [[1u8j]], [[1u8k]], [[1u8l]], [[1u8m]], [[1u8n]], [[1u8o]], [[1u8p]], [[1u8q]], [[1u91]], [[1u92]], [[1u93]], [[1u95]], [[2f5b]], [[3go1]], [[5drz]], [[4ydv]], [[6o42]] - hFab anti-HIV + gp41 peptide<br />
**[[3ghb]], [[3ghe]], [[3c2a]] - hFab anti-HIV + envelope glycoprotein peptide<br />
**[[3ghb]], [[3ghe]], [[3c2a]] - hFab anti-HIV + envelope glycoprotein peptide<br />
-
**[[3fn0]], [[2oqj]] - hFab + peptide<br />
+
**[[3fn0]], [[2oqj]], [[6fy3]], [[6ncp]] - hFab anti-HIV + peptide<br />
-
**[[2b0s]], [[2b1a]], [[2b1h]], [[3se8]], [[3se9]], [[4jkp]], [[4jpv]], [[4jb9]] - hFab anti-HIV + glycoprotein gp120 peptide<br />
+
**[[2b0s]], [[2b1a]], [[2b1h]], [[3se8]], [[3se9]], [[4jkp]], [[4jpv]], [[4jb9]], [[6vbo]], [[6vbp]], [[6vbq]] - hFab anti-HIV + glycoprotein gp120 peptide<br />
**[[1nak]], [[2f58]], [[3f58]], [[1f58]], [[1acy]], [[1qnz]] - mFab anti-HIV + glycoprotein gp120 peptide<br />
**[[1nak]], [[2f58]], [[3f58]], [[1f58]], [[1acy]], [[1qnz]] - mFab anti-HIV + glycoprotein gp120 peptide<br />
**[[1ai1]], [[1ggi]] – mFab anti-HIV + V3 peptide<br />
**[[1ai1]], [[1ggi]] – mFab anti-HIV + V3 peptide<br />
**[[3o6l]], [[3o6m]] - mFab 11H6H1 anti-HIV + Tat peptide<br />
**[[3o6l]], [[3o6m]] - mFab 11H6H1 anti-HIV + Tat peptide<br />
**[[1svz]] - mFab anti-HIV + HIV-2 protease peptide<br />
**[[1svz]] - mFab anti-HIV + HIV-2 protease peptide<br />
- 
*Human Fab: protein complex
*Human Fab: protein complex
Line 167: Line 204:
**[[3h42]] - hFab LDLR + proprotein convertase subtilisin/kexin<br />
**[[3h42]] - hFab LDLR + proprotein convertase subtilisin/kexin<br />
**[[3nh7]] – hFab ABD1556 + bone morphogenetic protein receptor<br />
**[[3nh7]] – hFab ABD1556 + bone morphogenetic protein receptor<br />
-
**[[3hi6]] – hFab AL-57 + integrin<br />
+
**[[3hi6]] – hFab + integrin<br />
 +
**[[6avq]], [[6avr]], [[6avu]] – hFab + integrin – Cryo EM<br />
**[[2vxs]], [[5fhx]] - hFab + interleukin<br />
**[[2vxs]], [[5fhx]] - hFab + interleukin<br />
**[[3b2u]], [[3b2v]] – hFab IMC-11F8 + EGFR<br />
**[[3b2u]], [[3b2v]] – hFab IMC-11F8 + EGFR<br />
Line 174: Line 212:
**[[6j71]] - hmFab + ERBB-2<br />
**[[6j71]] - hmFab + ERBB-2<br />
**[[3kr3]] – hFab + IGF-II<br />
**[[3kr3]] – hFab + IGF-II<br />
 +
**[[6yio]] – hFab + CD25<br />
 +
**[[6oel]] – hFab + IL-4R<br />
 +
**[[6p67]] – hFab + IL-7R<br />
 +
**[[7dc8]] – hFab + IL-6R<br />
 +
**[[6hga]], [[6ppg]] – hFab + IL-17R<br />
 +
**[[6plh]] – hFab + IL-21R<br />
 +
**[[6u6u]] – hFab + IL-36R<br />
 +
**[[6wzm]] – hFab + IL-8<br />
 +
**[[6ppg]], [[6wio]], [[6wir]] – hFab + IL-17<br />
**[[3g6d]] – hFab CNTO607 + IL-13<br />
**[[3g6d]] – hFab CNTO607 + IL-13<br />
**[[3g6j]] – hFab + complement C3<br />
**[[3g6j]] – hFab + complement C3<br />
**[[2wub]], [[3k2u]] – hFab 40 + hepatocyte growth factor activator<br />
**[[2wub]], [[3k2u]] – hFab 40 + hepatocyte growth factor activator<br />
 +
**[[6iz9]] – hFab + hepatocyte growth factor<br />
 +
**[[6i04]] – hFab + hepatocyte growth factor receptor<br />
 +
**[[6ktr]] - hFab + fibroblast growth factor <br />
**[[3grw]] - hFab + fibroblast growth factor receptor<br />
**[[3grw]] - hFab + fibroblast growth factor receptor<br />
 +
**[[6umx]] - hFab + growth factor 8<br />
**[[6ba5]] - hFab + tyrosine protein kinase receptor<br />
**[[6ba5]] - hFab + tyrosine protein kinase receptor<br />
-
**[[3bdy]], [[2qr0]], [[2fjg]], [[2fjh]], [[1cz8]], [[5fv2]], [[5fv1]] – hFab + VEGF<br />
+
**[[3bdy]], [[2qr0]], [[2fjg]], [[2fjh]], [[1cz8]], [[5fv2]], [[5fv1]], [[6t9d]] – hFab + VEGF<br />
**[[3bqu]] – hFab 2F5 anti-HIV + mFab 3H6<br />
**[[3bqu]] – hFab 2F5 anti-HIV + mFab 3H6<br />
**[[1adq]] – hFab IGM + igG1 Fc<br />
**[[1adq]] – hFab IGM + igG1 Fc<br />
 +
**[[6eyo]] – hFab + igE<br />
**[[3dvg]], [[3dvn]] – hFab igG1 + ubiquitin<br />
**[[3dvg]], [[3dvn]] – hFab igG1 + ubiquitin<br />
**[[3bn9]] – hFab E2 + membrane-type serine protease<br />
**[[3bn9]] – hFab E2 + membrane-type serine protease<br />
**[[2jix]] – hFab ABT-007 + erythropoietin receptor<br />
**[[2jix]] – hFab ABT-007 + erythropoietin receptor<br />
-
**[[1za3]] - hFab YSD1 + TNF receptor<br />
+
**[[1za3]], [[6t3j]] - hFab + TNF receptor<br />
 +
**[[6ogx]], [[6okm]], [[6okn]] - hFab + TNFRSF4<br />
**[[3l95]] – hFab + NRR1<br />
**[[3l95]] – hFab + NRR1<br />
**[[1uj3]], [[4dtg]] – hFab + tissue factor<br />
**[[1uj3]], [[4dtg]] – hFab + tissue factor<br />
**[[3lev]] – hFab 2F5 + RNA polymerase sigma factor<br />
**[[3lev]] – hFab 2F5 + RNA polymerase sigma factor<br />
-
**[[3ru8]], [[6mto]], [[6mtq]] – hFab + scaffold <br />
+
**[[3ru8]], [[6mto]], [[6mtq]], [[6s3d]] – hFab + scaffold <br />
**[[3skj]] – hFab + ephrin receptor<br />
**[[3skj]] – hFab + ephrin receptor<br />
**[[3sob]] – hFab + LPR6<br />
**[[3sob]] – hFab + LPR6<br />
Line 195: Line 248:
**[[5c8j]] – hFab + protein MJ0480<br />
**[[5c8j]] – hFab + protein MJ0480<br />
**[[4zso]] – hFab + natural cytotoxicity triggering receptor<br />
**[[4zso]] – hFab + natural cytotoxicity triggering receptor<br />
-
**[[4rrp]] - hFab + ASF1P <br />
+
**[[4rrp]], [[6ayz]], [[6az2]] - hFab + ASF1 <br />
-
**[[4qci]] - hFab + platelet factor B<br />
+
**[[4qci]], [[6t9e]] - hFab + platelet factor B<br />
**[[4mxv]] - hFab + lymphotoxin <br />
**[[4mxv]] - hFab + lymphotoxin <br />
-
**[[5dmj]], [[5ihl]] - hFab + CD40 <br />
+
**[[6al5]] - hFab + CD19 <br />
-
**[[3vg9]] – hFab + adenosine receptor<br />
+
**[[5dmj]], [[5ihl]], [[6fax]], [[6pe8]], [[6pe9]] - hFab + CD40 <br />
-
**[[3vga]] – hFab + adenosine receptor (mutant)<br />
+
**[[6hxw]] - hFab + CD73 <br />
 +
**[[3vg9]], [[3vga]] – hFab + adenosine receptor<br />
**[[2qqk]], [[2qql]], [[2qqn]] – hFab + neuropilin<br />
**[[2qqk]], [[2qql]], [[2qqn]] – hFab + neuropilin<br />
**[[2vyr]] – hFab + MDM4<br />
**[[2vyr]] – hFab + MDM4<br />
**[[6b0h]], [[6b0g]], [[6b0e]], [[6b0a]], [[6b08]], [[6azz]] - hFab + PFS25 <br />
**[[6b0h]], [[6b0g]], [[6b0e]], [[6b0a]], [[6b08]], [[6azz]] - hFab + PFS25 <br />
-
**[[6aod]], [[6hhc]] - hFab + coagulation factor <br />
+
**[[6aod]], [[6hhc]], [[6r8x]], [[7k66]] - hFab + coagulation factor <br />
-
**[[5oca]] - hFab + PCSK9 <br />
+
**[[5oca]], [[6u36]], [[6u38]] - hFab + PCSK9 <br />
**[[5n88]] - hFab + SFRS1-interacting protein <br />
**[[5n88]] - hFab + SFRS1-interacting protein <br />
**[[5bk1]], [[5bjz]] - hFab + maltose-binding protein <br />
**[[5bk1]], [[5bjz]] - hFab + maltose-binding protein <br />
-
**[[4hj0]] - hFab + GIPR <br />
+
**[[4hj0]], [[6dkj]] - hFab + GIPR <br />
**[[4g80]], [[4g7y]], [[4g7v]] - hFab + VSP <br />
**[[4g80]], [[4g7y]], [[4g7v]] - hFab + VSP <br />
**[[6cyf]] – hFab + secretion system protein<br />
**[[6cyf]] – hFab + secretion system protein<br />
Line 214: Line 268:
**[[6m58]] – hFab + serum albumin<br />
**[[6m58]] – hFab + serum albumin<br />
**[[6mvl]] – hFab + VISTA<br />
**[[6mvl]] – hFab + VISTA<br />
-
**[[6nmr]], [[6nms]], [[6nmt]], [[6nmu]], [[6nmv]] – hFab + SIRP-alpha<br />
+
**[[6bit]], [[6nmr]], [[6nms]], [[6nmt]], [[6nmu]], [[6nmv]], [[7kpg]] – hFab + SIRP-alpha<br />
**[[6o39]] – hFab + frizzled-5<br />
**[[6o39]] – hFab + frizzled-5<br />
**[[6o3a]], [[6o3b]] – hFab + frizzled-7<br />
**[[6o3a]], [[6o3b]] – hFab + frizzled-7<br />
Line 220: Line 274:
**[[6r0x]] – hFab + G6B<br />
**[[6r0x]] – hFab + G6B<br />
**[[6r2s]] – hFab + duffy receptor<br />
**[[6r2s]] – hFab + duffy receptor<br />
-
**[[6u8c]] – hFab + protein G<br />
+
**[[6o41]], [[6u8c]] – hFab + protein G<br />
**[[6xxv]] – hFab + S2_1.2<br />
**[[6xxv]] – hFab + S2_1.2<br />
-
 
+
**[[6ss2]], [[6ss4]], [[6ss6]] – hFab + arginase<br />
 +
**[[6hx4]] – hFab + cytokine receptor<br />
 +
**[[6e63]] – hFab + CSP <br />
 +
**[[6mb3]], [[6mhg]] – hFab + CSP – Cryo EM<br />
 +
**[[6c9u]], [[6mlk]] – hFab + DEBS<br />
 +
**[[6s5a]] – hFab + LALA<br />
 +
**[[6o9h]] – hFab + ECD<br />
 +
**[[6bfs]] – hFab + GM-CSF<br />
 +
**[[7dm1]], [[7dm2]] – hFab + PstS-1<br />
 +
**[[6vgr]] - hFab + dipeptidase<br />
 +
**[[6vvu]] - hFab + tryptase<br />
 +
**[[6j14]], [[6j15]] - hFab + PD-1<br />
 +
**[[6vc9]], [[6vca]] - hFab + nucleotidase<br />
 +
**[[6i3z]] - hFab anti-antitrypsin + antitrypsin<br />
 +
**[[6xy2]] – hFab + CTLA<br />
 +
**[[6wmw]] – hFab + GFRAL receptor<br />
 +
**[[6xmi]] – hFab + terminase<br />
 +
**[[6cbv]] – hFab + BRIL<br />
 +
**[[7khf]] – hFab + rifin<br />
 +
**[[6y9b]] – hFab + STEAP1<br />
 +
**[[6fn4]] – hFab + ABCB<br />
 +
**[[6bdz]] – hFab + ADAM-10<br />
 +
**[[7c61]] – hFab + HT1B<br />
 +
**[[6wzj]], [[6wzk]], [[6wzl]] – hFab + CXCL<br />
 +
**[[6m3b]], [[6m3c]] – hFab + vitamin K-dependent protein<br />
 +
**[[6j6y]] – sFab + FGFR4<br />
*Human Fab: viral protein complex
*Human Fab: viral protein complex
-
**[[6e3h]], [[6d0u]], [[5vag]], [[3gbm]], [[3gbn]], [[3lzf]], [[3fku]], [[3sdy]], [[3ztj]], [[3ztn]], [[4fp8]], [[4fqi]], [[4fqj]], [[4fqk]], [[4fql]], [[4fqr]], [[4fqv]], [[4fqy]], [[4gxu]], [[4nm8]], [[5gjt]], [[5gjs]], [[5dur]], [[5c0s]], [[4yk4]], [[4py8]], [[5wko]], [[5w6g]], [[5w0d]], [[5w08]], [[5v2a]], [[5umn]], [[5kaq]], [[6ml8]], [[6e56]], [[4r8w]] – hFab + Influenza virus hemagglutinin<br />
+
**[[6e3h]], [[6d0u]], [[5vag]], [[3gbm]], [[3gbn]], [[3lzf]], [[3fku]], [[3sdy]], [[3ztj]], [[3ztn]], [[4fp8]], [[4fqi]], [[4fqj]], [[4fqk]], [[4fql]], [[4fqr]], [[4fqv]], [[4fqy]], [[4gxu]], [[4nm8]], [[5gjt]], [[5gjs]], [[5dur]], [[5c0s]], [[4yk4]], [[4py8]], [[5wko]], [[5w6g]], [[5w0d]], [[5w08]], [[5v2a]], [[5umn]], [[5kaq]], [[6b3m]], [[6cnv]], [[6e4x]], [[6ii4]], [[6ii8]], [[6ii9]], [[6ml8]], [[6e56]], [[4r8w]], [[6iut]], [[6iuv]], [[6mlm]], [[6oc3]], [[6ocb]], [[6p3r]], [[6p3s]], [[6pdx]], [[6q0e]], [[6q0h]], [[6q0i]], [[6q0l]], [[6q0o]], [[6q18]], [[6uig]], [[6ur5]], [[6urm]], [[6uyn]], [[6wex]], [[6wez]], [[6wf0]], [[6wf1]], [[6wiz]], [[6wj1]], [[7kqg]], [[7kqh]], [[7kqi]] – hFab + Influenza virus hemagglutinin<br />
-
**[[6pzy]], [[6pzz]] – hFab + Influenza virus neuraminidase<br />
+
**[[7k37]], [[7k39]], [[7k3a]], [[7k3b]] – hFab + Influenza virus hemagglutinin – Cryo EM<br />
-
**[[5gzo]], [[5gzn]], [[6dfi]], [[6dfj]], [[5lcv]] – hFab + zika polyprotein<br />
+
**[[6pze]], [[6pzf]], [[6pzy]], [[6pzz]], [[6q1z]], [[6q20]], [[6q23]], [[6u02]] – hFab + Influenza virus neuraminidase<br />
-
**[[5hj3]], [[5fhc]] – hFab + ebola envelope protein<br />
+
**[[6pzw]], [[6pzy]], [[6pzz]], [[6v4n]], [[6v4o]] – hFab + Influenza virus neuraminidase – Cryo EM<br />
 +
**[[5gzo]], [[5gzn]], [[6dfi]], [[6dfj]], [[5lcv]], [[6jep]], [[6nip]], [[6niu]], [[6plk]] – hFab + zika protein<br />
 +
**[[6jfh]], [[6jfi]], [[6lnt]], [[7bu8]], [[7bua]], [[7c2t]], [[7kcr]] – hFab + zika proteins – Cryo EM<br />
 +
**[[5hj3]], [[5fhc]], [[6oz9]], [[6s8d]], [[6s8i]], [[6s8j]] – hFab + ebola envelope protein<br />
**[[6dzm]], [[6uye]] – hFab + ebola spike proteins – Cryo EM<br />
**[[6dzm]], [[6uye]] – hFab + ebola spike proteins – Cryo EM<br />
-
**[[6mej]], [[6meh]], [[6mei]] – hFab + hepacivirus glycoprotein<br />
 
**[[5n09]], [[4utb]], [[4uta]], [[4ut9]], [[4ut6]] – hFab + dengue virus envelope protein <br />
**[[5n09]], [[4utb]], [[4uta]], [[4ut9]], [[4ut6]] – hFab + dengue virus envelope protein <br />
-
**[[4c2i]] – hFab + dengue virus envelope protein - Cryo EM<br />
+
**[[4c2i]], [[7bub]], [[7bud]], [[7bue]], [[7buf]], [[7c2s]] – hFab + dengue virus envelope protein - Cryo EM<br />
 +
**[[6weq]], [[6wer]], [[7bsc]], [[7bsd]] – hFab + dengue virus NS1c <br />
 +
**[[6cmg]], [[6cmi]], [[6vy4]], [[6vy6]] – hFab + Hendra virus protein<br />
 +
**[[6ute]] – hFab + West NIle virus protein<br />
 +
**[[6vy5]] – hFab + nipa virus receptor binding protein<br />
 +
**[[6blh]], [[6bli]], [[6oe4]], [[6ous]], [[6w52]] – hFab + RSV fusion protein<br />
 +
**[[6mjz]] – hFab + respirovirus fusion protein<br />
 +
**[[6ce0]], [[6vlw]], [[6w16]] – hFab + HIV-1 protein<br />
 +
**[[6w7s]], [[6wh9]] – hFab + KR1<br />
 +
**[[6ddm]], [[6ddv]] – hFab + MHC<br />
**[[4dag]] – hFab + metapneumovirus glycoprotein F0<br />
**[[4dag]] – hFab + metapneumovirus glycoprotein F0<br />
**[[6p91]], [[6p95]] – hFab + lassa mammarenavirus glycoprotein <br />
**[[6p91]], [[6p95]] – hFab + lassa mammarenavirus glycoprotein <br />
-
**[[6c6z]], [[4xak]] - hFab + coronavirus spike protein <br />
+
**[[6h2y]] – hFab + Neisseria lipoprotein<br />
-
**[[6z2m]] - hFab + coronavirus spike protein + nanobody<br />
+
**[[7cvz]], [[7cvy]], [[7cw0]], [[7cw2]], [[7cw3]] – hFab + chikungunyavirus proteins – Cryo EM<br />
-
**[[7bwj]] - hFab + coronavirus receptor RBD <br />
+
**[[6nb3]], [[6nb4]] - hFab + MERS-CoV spike protein – Cryo EM<br />
-
**[[6wps]], [[6wpt]] - hFab + coronavirus spike protein – Cryo EM<br />
+
**[[6xob]] – hFab + eastern equine encephalitis virus protein - Cryo EM<br />
-
 
+
**[[6yo6]] – hFab + LgHC3NB1<br />
 +
**[[6b9j]] – sFab + vaccinia virus protein<br />
 +
**[[6otc]] – sFab + Marburg virus protein<br />
 +
**[[6svl]] – sFab + MYDGF<br />
*Mouse Fab: protein complex
*Mouse Fab: protein complex
Line 250: Line 343:
**[[3o0r]], [[5gux]] – mFab + nitric oxide reductase<br />
**[[3o0r]], [[5gux]] – mFab + nitric oxide reductase<br />
**[[1ahw]] - mFab 5G9+ tissue factor<br />
**[[1ahw]] - mFab 5G9+ tissue factor<br />
-
**[[2w9e]], [[1tpx]], [[1tqb]], [[1tqc]] – mFAB + major prion protein<br />
+
**[[2w9e]], [[1tpx]], [[1tqb]], [[1tqc]], [[6aq7]], [[6suz]], [[6sv2]] – mFAB + major prion protein<br />
**[[2oz4]] – mFab + intercellular adhesion molecule<br />
**[[2oz4]] – mFab + intercellular adhesion molecule<br />
**[[3eo1]] - mFab GC-1008 + transforming growth factor β-3<br />
**[[3eo1]] - mFab GC-1008 + transforming growth factor β-3<br />
 +
**[[6z7w]], [[6z7y]], [[6z7z]] – mFab + insulin<br />
**[[4zxb]] – mFab 83 + insulin receptor<br />
**[[4zxb]] – mFab 83 + insulin receptor<br />
**[[1egj]] – mFab + cytokine receptor<br />
**[[1egj]] – mFab + cytokine receptor<br />
Line 260: Line 354:
**[[1qfw]] – mFab + gonadotropin<br />
**[[1qfw]] – mFab + gonadotropin<br />
**[[4cad]] – mFab + RCE1<br />
**[[4cad]] – mFab + RCE1<br />
-
**[[4m48]], [[4xpt]], [[4xph]], [[4xpg]], [[4xpf]], [[4xpb]], [[4xpa]], [[4xp9]], [[4xp6]], [[4xp5]], [[4xp4]], [[4xp1]], [[4xnx]], [[4xnu]] – mFab + dopamine transporter<br />
+
**[[4m48]], [[4xpt]], [[4xph]], [[4xpg]], [[4xpf]], [[4xpb]], [[4xpa]], [[4xp9]], [[4xp6]], [[4xp5]], [[4xp4]], [[4xp1]], [[4xnx]], [[4xnu]], [[6m0f]], [[6m3z]] – mFab + dopamine transporter<br />
**[[5i75]], [[5i74]], [[5i73]], [[5i71]], [[5i6z]], [[5i6x]], [[6awq]], [[6awp]], [[6awo]], [[6awn]], [[6w2b]], [[6w2c]] – mFab + serotonin transporter<br />
**[[5i75]], [[5i74]], [[5i73]], [[5i71]], [[5i6z]], [[5i6x]], [[6awq]], [[6awp]], [[6awo]], [[6awn]], [[6w2b]], [[6w2c]] – mFab + serotonin transporter<br />
**[[6dzv]], [[6dzw]], [[6dzy]], [[6dzz]], [[6vrh]], [[6vrk]], [[6vrl]] – mFab + serotonin transporter – Cryo EM<br />
**[[6dzv]], [[6dzw]], [[6dzy]], [[6dzz]], [[6vrh]], [[6vrk]], [[6vrl]] – mFab + serotonin transporter – Cryo EM<br />
Line 268: Line 362:
**[[4r0l]] – mFab + CD28<br />
**[[4r0l]] – mFab + CD28<br />
**[[4qex]], [[4k2u]] – mFab + erythrocyte binding antigen<br />
**[[4qex]], [[4k2u]] – mFab + erythrocyte binding antigen<br />
-
**[[2r9h]], [[6ad7]], [[6ad8]], [[6ada]], [[6adb]], [[6adc]] – mFab + exchange transporter ClCA<br />
+
**[[2r9h]], [[6ad7]], [[6ad8]], [[6ada]], [[6adb]], [[6adc]], [[6k5a]], [[6k5i]] – mFab + exchange transporter ClCA<br />
**[[1rjl]] – mFab + outer surface protein<br />
**[[1rjl]] – mFab + outer surface protein<br />
**[[1mhh]] – mFab + protein L (mutant)<br />
**[[1mhh]] – mFab + protein L (mutant)<br />
Line 294: Line 388:
**[[5d96]], [[5d93]] - mFab + sulfhydryl oxidase<br />
**[[5d96]], [[5d93]] - mFab + sulfhydryl oxidase<br />
**[[4ybq]] – mFab + fructose transporter<br />
**[[4ybq]] – mFab + fructose transporter<br />
-
**[[4xzu]] - mFab + coagulation factor <br />
+
**[[4xzu]], [[7kbt]] - mFab + coagulation factor <br />
**[[4u6h]] - mFab + virion membrane protein M25 <br />
**[[4u6h]] - mFab + virion membrane protein M25 <br />
**[[4r9y]], [[4r97]] - mFab + platelet factor 4<br />
**[[4r9y]], [[4r97]] - mFab + platelet factor 4<br />
Line 305: Line 399:
**[[5ldn]] – mFab + hexon C5<br />
**[[5ldn]] – mFab + hexon C5<br />
**[[5ldn]] – mFab + MIG-C4<br />
**[[5ldn]] – mFab + MIG-C4<br />
-
 
+
**[[6ule]], [[6x87]] – mFab + CSP – Cryo EM<br />
 +
**[[6vx4]] – mFab + toxins – Cryo EM<br />
 +
**[[6elu]] – mFab + Trypanosoma protein<br />
 +
**[[6k65]] – mFab + immunoglobulin G-binding protein<br />
 +
**[[6ks0]], [[6ks1]] – mFab + adiponectin receptor protein<br />
 +
**[[6p50]] – mFab + IL-17R<br />
 +
**[[6sxi]] – mFab + scFv<br />
 +
**[[6z2l]] – mFab + P113<br />
 +
**[[6ohg]] – mFab + P230<br />
 +
**[[7kr5]] – mFab + CRAC – Cryo EM<br />
 +
**[[6nyq]] – mFab + GLMP<br />
 +
**[[6vtw]] – mFab + RSV S4<br />
 +
**[[7a65]] – mFab + ABCB – Cryo EM<br />
*Mouse Fab: viral protein complex
*Mouse Fab: viral protein complex
Line 311: Line 417:
**[[6a0z]], [[1eo8]], [[1ken]], [[4mhh]], [[4mhj]], [[6n5b]], [[6n5d]] - mFab anti-influenza virus hemagglutinin<br />
**[[6a0z]], [[1eo8]], [[1ken]], [[4mhh]], [[4mhj]], [[6n5b]], [[6n5d]] - mFab anti-influenza virus hemagglutinin<br />
**[[4qnp]], [[1nca]], [[1ncb]], [[1ncc]], [[1ncd]] – mFab + influenza neuraminidase<br />
**[[4qnp]], [[1nca]], [[1ncb]], [[1ncc]], [[1ncd]] – mFab + influenza neuraminidase<br />
 +
**[[6n5e]] – mFab + influenza hemagglutinin <br />
 +
**[[6wzt]] – mFab + influenza hemagglutinin – Cryo EM<br />
**[[1rvf]] – mFab 17-IA + intact rhinovirus<br />
**[[1rvf]] – mFab 17-IA + intact rhinovirus<br />
**[[3j3o]], [[3j3p]]- mFab + poliovirus proteins – cryoEM<br />
**[[3j3o]], [[3j3p]]- mFab + poliovirus proteins – cryoEM<br />
Line 316: Line 424:
**[[6j5g]], [[6j5f]] - mFab + tick-borne encephalitis virus protein <br />
**[[6j5g]], [[6j5f]] - mFab + tick-borne encephalitis virus protein <br />
**[[6j5d]] - mFab + louping ILL virus protein – cryoEM<br />
**[[6j5d]] - mFab + louping ILL virus protein – cryoEM<br />
-
**[[5kvg]], [[5kvf]], [[5kve]], [[5kvd]], [[5jhl]] – mFab + zika envelope DIII <br />
+
**[[5kvg]], [[5kvf]], [[5kve]], [[5kvd]], [[5jhl]], [[6uta]] – mFab + zika envelope DIII <br />
**[[3ve0]] - mFab + Ebola envelope glycoprotein<br />
**[[3ve0]] - mFab + Ebola envelope glycoprotein<br />
**[[5y9t]], [[5y9c]], [[5y9f]] – mFab + papilloma virus capsid protein<br />
**[[5y9t]], [[5y9c]], [[5y9f]] – mFab + papilloma virus capsid protein<br />
-
**[[4l5f]] – mFab + dengue virus envelope protein <br />
+
**[[4l5f]], [[6fla]], [[6flb]], [[6flc]] – mFab + dengue virus envelope protein <br />
-
**[[5zud]], [[5zuf]] – mFab + enterovirus caspid proteins – Cryo EM<br />
+
**[[5zud]], [[5zuf]], [[6aj7]], [[6aj9]], [[7ebz]], [[7ec5]], [[7ecy]] – mFab + enterovirus caspid proteins – Cryo EM<br />
**[[6tys]] – mFab + nipa virus fusion protein – Cryo EM<br />
**[[6tys]] – mFab + nipa virus fusion protein – Cryo EM<br />
**[[3fmg]] – mFab + rotavirus glycoprotein VP7<br />
**[[3fmg]] – mFab + rotavirus glycoprotein VP7<br />
**[[3ixx]], [[3ixy]] - mFab E53 + envelope glycoprotein + West Nile virus peptide<br />
**[[3ixx]], [[3ixy]] - mFab E53 + envelope glycoprotein + West Nile virus peptide<br />
 +
**[[6pxh]], [[6pz8]], [[7eam]] - mFab anti-MERS-CoV + MERS-CoV protein<br />
 +
*Anti-HIV Fab: protein complex or broadly neutralizing antibody complex
-
*Anti-HIV Fab: protein complex
+
**[[3mac]], [[3ma9]], [[6fy1]] – hFab anti-HIV 8062 + transmembrane glycoprotein<br />
-
 
+
**[[3idx]], [[3idy]], [[2ny7]], [[4jpw]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lss]], [[4lst]], [[4lsu]], [[4lsv]], [[5te4]], [[5fyl]], [[5f9w]], [[5f96]], [[5f6j]], [[4ywg]], [[4ye4]], [[4ydl]], [[4ydk]], [[4ydj]], [[4ydi]], [[4yc2]], [[4ybl]], [[4s1s]], [[4s1r]], [[4s1q]], [[4rwy]], [[4rfn]], [[5w4l]], [[5uwe]], [[6bck]], [[6bf4]], [[6d2p]], [[6db5]], [[6oej]], [[6ofi]] - hFab anti-HIV + gp120 core<br />
-
**[[3mac]], [[3ma9]] – hFab anti-HIV 8062 + transmembrane glycoprotein<br />
+
**[[6b0n]] - hFab anti-HIV + gp140<br />
-
**[[3idx]], [[3idy]], [[2ny7]], [[4jpw]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lss]], [[4lst]], [[4lsu]], [[4lsv]], [[5te4]], [[5fyl]], [[5f9w]], [[5f96]], [[5f6j]], [[4ywg]], [[4ye4]], [[4ydl]], [[4ydk]], [[4ydj]], [[4ydi]], [[4yc2]], [[4ybl]], [[4s1s]], [[4s1r]], [[4s1q]], [[4rwy]], [[4rfn]], [[5w4l]], [[6w4m]] - hFab anti-HIV + gp120 core<br />
+
**[[5v7j]], [[4j6r]] - hFab anti-HIV + gp160<br />
**[[5v7j]], [[4j6r]] - hFab anti-HIV + gp160<br />
-
**[[6pwu]] - hFab anti-HIV + gp160 – Cryo EM<br />
+
**[[6dfg]], [[6dfh]], [[6e5p]], [[6pwu]] - hFab anti-HIV + gp160 – Cryo EM<br />
**[[4xnz]], [[4xny]], [[4xmp]] - hFab anti-HIV + gp41<br />
**[[4xnz]], [[4xny]], [[4xmp]] - hFab anti-HIV + gp41<br />
-
**[[6orn]], [[6oro]], [[6orp]], [[6orq]] - hFab anti-HIV + gp41 + gp120<br />
+
**[[6ccb]], [[6mft]], [[6orn]], [[6oro]], [[6orp]], [[6orq]], [[6utk]], [[6v6w]] - hFab anti-HIV + gp41 + gp120<br />
-
**[[6ulc]] - hFab anti-HIV + gp41 + gp120 – Cryo EM<br />
+
**[[6nij]], [[6nqd]], [[6ulc]], [[6um5]], [[6um6]], [[6um7]], [[6vo3]], [[6vy2]], [[7ll1]] - hFab anti-HIV + gp41 + gp120 – Cryo EM<br />
 +
**[[6opa]], [[6oz4]] - hFab anti-HIV + gp41 + gp160<br />
 +
**[[6ozc]] - hFab anti-HIV + gp41 + gp160 – Cryo EM<br />
 +
**[[6u0l]], [[6u0n]] - hFab anti-HIV + gp41 + gp160 + CD4 – Cryo EM<br />
 +
**[[6mg7]], [[6w4m]] - hFab anti-HIV + gp120 + M48U1<br />
**[[6vpx]] - hFab anti-HIV + gp41 + gp120 + MPER peptide – Cryo EM<br />
**[[6vpx]] - hFab anti-HIV + gp41 + gp120 + MPER peptide – Cryo EM<br />
**[[5tfw]], [[5t85]], [[5t80]], [[5t6l]], [[5t5b]], [[5t29]] - hFab anti-HIV + T117V2<br />
**[[5tfw]], [[5t85]], [[5t80]], [[5t6l]], [[5t5b]], [[5t29]] - hFab anti-HIV + T117V2<br />
**[[2x7l]] – hFab anti-HIV + HIV REV<br />
**[[2x7l]] – hFab anti-HIV + HIV REV<br />
 +
**[[6cdm]], [[6cdo]], [[6cdp]], [[6ch8]], [[6ch9]], [[6chb]], [[6ck9]], [[6cxg]], [[6fy2]], [[6muf]], [[6myy]], [[6mzj]], [[6w03]] – hFab anti-HIV + HIV protein<br />
 +
**[[6cde]], [[6cdi]], [[6edu]], [[7kde]] – hFab anti-HIV + HIV protein – Cryo EM<br />
 +
**[[6uuh]] – hFab anti-HIV + IggG<br />
 +
**[[6mam]] – hFab anti-HIV + ebola glycoprotein<br />
 +
**[[6qd7]], [[6qd8]] – hFab anti-HIV + ebola glycoprotein – Cryo EM<br />
 +
**[[6id4]] – hFab anti-HIV + MHC antigen + beta-2-microglobulin<br />
 +
**[[6vkn]], [[6vn0]], [[6xrt]] - rmFab anti-HIV + gp41 + gp160 – Cryo EM<br />
 +
**[[6vlr]] – rmFab anti-HIV + HIV protein<br />
 +
**[[6pw6]], [[6vo1]] - bFab anti-HIV + gp41 + gp120 – Cryo EM<br />
**[[1afv]] – mFab anti-HIV + capsid protein C<br />
**[[1afv]] – mFab anti-HIV + capsid protein C<br />
-
 
+
**[[6p8m]] - mFab anti-HIV + gp120 core<br />
*Other Fab: protein complex
*Other Fab: protein complex
Line 352: Line 474:
**[[4ht1]] – rFab + TNF ligand 12 <br />
**[[4ht1]] – rFab + TNF ligand 12 <br />
**[[6cf2]] – rFab + REV<br />
**[[6cf2]] – rFab + REV<br />
-
**[[6p65]] – rFab + HIV protein – Cryo EM<br />
+
**[[6cez]], [[6p65]], [[6vo0]] – rFab anti-HIV + HIV protein – Cryo EM<br />
**[[6osh]], [[6osv]] – rFab + ROR2<br />
**[[6osh]], [[6osv]] – rFab + ROR2<br />
**[[2r56]] – bFab igE + β-lactoglobulin <br />
**[[2r56]] – bFab igE + β-lactoglobulin <br />
Line 358: Line 480:
**[[4hgk]] – Fab + albumin – shark<br />
**[[4hgk]] – Fab + albumin – shark<br />
**[[4n9g]] - rmFab + scaffold<br />
**[[4n9g]] - rmFab + scaffold<br />
-
**[[6mqc]], [[6mqe]], [[6mqm]], [[6mqr]], [[6mqs]], [[6n16]] - rmFab + HIV fusion peptide<br />
+
**[[6mqc]], [[6mqe]], [[6mqm]], [[6mqr]], [[6mqs]], [[6n16]], [[6pds]], [[6pec]], [[6pef]] - rmFab + HIV fusion peptide<br />
**[[6tyb]] - rmFab + SIV gp160<br />
**[[6tyb]] - rmFab + SIV gp160<br />
 +
**[[6xgc]] – rmFab + Influenza virus hemagglutinin – Cryo EM<br />
 +
**[[6xcj]] - rmFab anti-HIV + gp120 core<br />
 +
**[[6z06]], [[7b09]] - Fab + envelope polyprotein - vole<br />
**[[6oor]] – raFab + β-2-microglobulin + CD1D<br />
**[[6oor]] – raFab + β-2-microglobulin + CD1D<br />
-
**[[6h5n]] – raFab + malaria protein<br />
+
**[[6e62]], [[6h5n]] – raFab + malaria protein<br />
**[[6qig]] – raFab + ADAMTS-13<br />
**[[6qig]] – raFab + ADAMTS-13<br />
-
**[[6p60]] - Fab + HIV fusion peptide - platytthini<br />
+
**[[6al0]], [[6al1]], [[6icc]], [[6icf]] – raFab + S2P<br />
 +
**[[7k23]] – raFab + VP1<br />
 +
**[[7k22]] – raFab + VP4<br />
 +
**[[6gku]] – LgFab + galectin<br />
 +
**[[6vi1]] – syFab + terminase<br />
 +
**[[6iap]] – syFab + Nkp46<br />
 +
**[[6p60]], [[6p7h]] - Fab + HIV fusion peptide - platytthini<br />
**[[6i8s]] - Fab + plasminogen activator inhibitor – Escherichia coli<br />
**[[6i8s]] - Fab + plasminogen activator inhibitor – Escherichia coli<br />
**[[6pis]] – Fab + TRAAK – Cricetulus migratorius<br />
**[[6pis]] – Fab + TRAAK – Cricetulus migratorius<br />
- 
*Human Fab: protein higher complexes
*Human Fab: protein higher complexes
Line 382: Line 512:
**[[6gv4]] – hFab + parechovirus proteins + RNA - Cryo EM<br />
**[[6gv4]] – hFab + parechovirus proteins + RNA - Cryo EM<br />
**[[6cw2]] – hFab + histone acetyltransferase + transcriptional adapter<br />
**[[6cw2]] – hFab + histone acetyltransferase + transcriptional adapter<br />
-
**[[6c5v]] – hFab + herpesvirus proteins - Cryo EM<br />
+
**[[6uoe]] – hFab + herpesvirus proteins <br />
 +
**[[6c5v]], [[7kdd]], [[7lbe]], [[7lbf]] – hFab + herpesvirus proteins - Cryo EM<br />
**[[6c08]] – hFab + amino acid transporter + Arg<br />
**[[6c08]] – hFab + amino acid transporter + Arg<br />
-
 
+
**[[6w00]], [[6wfw]] – hFab + immunoglobulin G-binding protein + CSP peptide<br />
 +
**[[6apd]] – hFab + RSV fusion protein + immunoglobulin + IGL <br />
 +
**[[6w51]] – hFab + 2-b-microglobulin + MHC + p53 peptide<br />
 +
**[[6o24]], [[6o25]], [[6o28]], [[6o29]], [[6o2a]], [[6o2b]], [[6o2c]], [[6ulf]], [[6vln]] – hFab + LgVHH + CSP<br />
 +
**[[6o1f]] - hFab + trypsin inhibitor + tryptase<br />
 +
**[[7joo]] - hFab + LgVHH + ICOS<br />
 +
**[[6fn1]] – hFab + ABCB + drug<br />
 +
**[[7a69]] – hFab + ABCB + drug – Cryo EM<br />
 +
**[[6w9g]] - hFab + CD40 + fluorescent amino acid<br />
 +
**[[6e0c]], [[6e0p]] - hscFv in nucleosome – Cryo EM<br />
 +
**[[6ww2]] – hFab + syVHH + frizzled-5 – Cryo EM<br />
*Human anti-HIV Fab: protein higher complexes
*Human anti-HIV Fab: protein higher complexes
Line 392: Line 533:
**[[4r4n]], [[4r4f]] - hFab anti-HIV + envelope glycoprotein gp120 + M48U1 peptide<br />
**[[4r4n]], [[4r4f]] - hFab anti-HIV + envelope glycoprotein gp120 + M48U1 peptide<br />
**[[3lqa]], [[2qad]] - hFab anti-HIV + CD4 + gp41<br />
**[[3lqa]], [[2qad]] - hFab anti-HIV + CD4 + gp41<br />
-
 
+
**[[6mtj]], [[6mtn]], [[6mu6]], [[6mu7]], [[6mu8]], [[6mug]] - hFab anti-HIV + HIV proteins + inhibitor<br />
*Mouse Fab: protein higher complexes
*Mouse Fab: protein higher complexes
Line 406: Line 547:
**[[6jmq]], [[6jmr]] – mFab + large neutral amino acid transporter + 4f2 cell-surface antigen<br />
**[[6jmq]], [[6jmr]] – mFab + large neutral amino acid transporter + 4f2 cell-surface antigen<br />
**[[6qno]] - mFab + guanine nucleotide-binding protein + transducin + rhodopsin – Cryo EM<br />
**[[6qno]] - mFab + guanine nucleotide-binding protein + transducin + rhodopsin – Cryo EM<br />
-
 
+
**[[7k78]] - mFab + yeast nucleosome – Cryo EM<br />
 +
**[[7c6a]] – mFab + angiotensin receptor + SAR1<br />
 +
**[[6gff]] – mFab + TGF + GARPIN<br />
 +
**[[7a6e]], [[7a6f]] – mFab + ABCB + drug – Cryo EM<br />
*Full Immunoglobulin
*Full Immunoglobulin
Line 413: Line 557:
**[[1iga]] - hIgA1 - model<br />
**[[1iga]] - hIgA1 - model<br />
-
*Fc Fragments
+
*Fc Fragments or immunoglobulin gamma-1 heavy chain
-
**[[3dnk]] - hFc Igg1br />
+
**[[3dnk]] - hFc Igg1<br />
**[[1qp1]] – hFc BRE<br />
**[[1qp1]] – hFc BRE<br />
**[[3muh]] – hFc PG9<br />
**[[3muh]] – hFc PG9<br />
Line 421: Line 565:
**[[1f6a]] - hFc IgE + high-affinity receptor Fc (ε) RI (α)<br />
**[[1f6a]] - hFc IgE + high-affinity receptor Fc (ε) RI (α)<br />
**[[1fp5]] - hFc IgE C ε 3-C ε 4<br />
**[[1fp5]] - hFc IgE C ε 3-C ε 4<br />
-
 
+
**[[6cjx]], [[6f2z]], [[6x3i]] - hFc (mutant) <br />
 +
**[[6iqg]] - hFc + peptide<br />
 +
**[[6d4i]] - rmFc Igg2<br />
 +
**[[6d4e]], [[6d4m]] - rmFc Igg3<br />
 +
**[[6d4n]] - rmFc Igg4<br />
*Fv Fragments
*Fv Fragments
Line 427: Line 575:
**[[3zhd]], [[3zhk]], [[3zhl]] – hFv scaffold<br />
**[[3zhd]], [[3zhk]], [[3zhl]] – hFv scaffold<br />
**[[4u3x]] – hFv + lysozyme<br />
**[[4u3x]] – hFv + lysozyme<br />
 +
**[[6dzl]] – hFv + ebola protein – Cryo EM<br />
**[[3dur]], [[3dus]], [[3duu]], [[3dv4]], [[3dv6]] – mFv + Ig-like protein<br />
**[[3dur]], [[3dus]], [[3duu]], [[3dv4]], [[3dv6]] – mFv + Ig-like protein<br />
**[[3hb3]] – mFv + cytochrome c oxidase subunit 1-β<br />
**[[3hb3]] – mFv + cytochrome c oxidase subunit 1-β<br />
**[[1qle]] - mFv + cytochrome c oxidase<br />
**[[1qle]] - mFv + cytochrome c oxidase<br />
**[[6oik]] - mFv + AChR + guanine nucleotide-binding protein + transducin – Cryo EM<br />
**[[6oik]] - mFv + AChR + guanine nucleotide-binding protein + transducin – Cryo EM<br />
- 
* Single chain variable fragment (scFv)
* Single chain variable fragment (scFv)
-
**[[6ehy]], [[6ehv]], [[6ehw]], [[6ehx]], [[5c2b]], [[5wym]], [[1x9q]], [[2a9m]], [[3kdm]], [[4buh]], [[3u6r]], [[3auv]] – hscFv <br />
+
**[[6ehy]], [[6ehv]], [[6ehw]], [[6ehx]], [[5c2b]], [[5wym]], [[1x9q]], [[2a9m]], [[3kdm]], [[4buh]], [[3u6r]], [[3auv]], [[6qb9]], [[6qf9]], [[6vrp]], [[7ah1]] – hscFv <br />
-
**[[4x4x]], [[6dn0]], [[2a9n]] – hscFv (mutant)<br />
+
**[[4x4x]], [[4x4y]], [[2a9n]], [[6vun]], [[6vuo]], [[6vup]], [[7kbm]], [[7kbo]] – hscFv (mutant)<br />
**[[3juy]], [[4ut7]] – hscFv anti-HIV<br />
**[[3juy]], [[4ut7]] – hscFv anti-HIV<br />
-
**[[4h0g]], [[4nkd]], [[4nkm]], [[4nko]], [[3nn8]], [[3bd3]], [[3bd4]], [[3bd5]], [[2gjj]], [[5b3n]], [[4laq]], [[4gqp]], [[3umt]] – mscFv <br />
+
**[[6j9o]] – hscFv anti-influenza<br />
 +
**[[6ffj]] – hscFv anti-tumor<br />
 +
**[[6uup]], [[6uy3]] – cscFv - camel <br />
 +
**[[6pil]], [[6psc]] – rscFv <br />
 +
**[[4h0g]], [[4nkd]], [[4nkm]], [[4nko]], [[3nn8]], [[3bd3]], [[3bd4]], [[3bd5]], [[2gjj]], [[5b3n]], [[4laq]], [[4gqp]], [[3umt]], [[6s2i]], [[6tnp]] – mscFv <br />
**[[1p4i]] – mscFv (mutant)<br />
**[[1p4i]] – mscFv (mutant)<br />
**[[4p49]], [[4p48]], [[4ouo]], [[5vf6]] – scFv - chicken<br />
**[[4p49]], [[4p48]], [[4ouo]], [[5vf6]] – scFv - chicken<br />
-
 
+
**[[6wzn]] – syscFv <br />
* Single chain variable fragment complex
* Single chain variable fragment complex
Line 448: Line 600:
**[[5ljy]] – hscFv + Hantaan virus envelope protein<br />
**[[5ljy]] – hscFv + Hantaan virus envelope protein<br />
**[[6pcu]] – hscFv + rotavirus capsid protein<br />
**[[6pcu]] – hscFv + rotavirus capsid protein<br />
-
**[[5wn9]] – hscFv + respiratory syncytial virus envelope protein<br />
+
**[[5wn9]] – hscFv + RSV envelope protein<br />
**[[4nik]] – hscFv + gankyrin<br />
**[[4nik]] – hscFv + gankyrin<br />
**[[5jz7]] – hscFv + NGF<br />
**[[5jz7]] – hscFv + NGF<br />
**[[4kv5]] – hscFv + TGF<br />
**[[4kv5]] – hscFv + TGF<br />
 +
**[[6tou]] – hscFv + rabies glycoprotein<br />
 +
**[[6ikm]] – hscFv + polyamine transport protein<br />
**[[2ybr]], [[2yc1]] – hscFv + CN2 toxin<br />
**[[2ybr]], [[2yc1]] – hscFv + CN2 toxin<br />
**[[5ujz]], [[5uk0]], [[5uk1]], [[5uk2]] - hscFv + hemagglutinin – Cryo EM<br />
**[[5ujz]], [[5uk0]], [[5uk1]], [[5uk2]] - hscFv + hemagglutinin – Cryo EM<br />
**[[4v1d]] - hscFv + mammal toxin CN2 <br />
**[[4v1d]] - hscFv + mammal toxin CN2 <br />
-
**[[5dhz]], [[5dhy]], [[5dhx]], [[5dhv]] – hscFv anti-HIV + HIV REV<br />
+
**[[6i07]] – hscFv + EpCAM<br />
 +
**[[6kn9]] – hscFv + IL-18R<br />
 +
**[[5d9q]] – hscFv + antibody + gp120 + gp40<br />
 +
**[[5dhz]], [[5dhy]], [[5dhx]], [[5dhv]], [[6cbp]], [[6nnf]] – hscFv anti-HIV + HIV protein<br />
**[[3ab0]] – mscFv + BCLA protein<br />
**[[3ab0]] – mscFv + BCLA protein<br />
**[[5jyl]], [[5jym]] – mscFv + cadherin<br />
**[[5jyl]], [[5jym]] – mscFv + cadherin<br />
Line 466: Line 623:
**[[3h3b]], [[6eqc]] – mscFv + hexon protein – Cryo EM<br />
**[[3h3b]], [[6eqc]] – mscFv + hexon protein – Cryo EM<br />
**[[4f9p]], [[4f9l]] – mscFv + BTN3A1<br />
**[[4f9p]], [[4f9l]] – mscFv + BTN3A1<br />
-
**[[5aam]], [[5aaw]] – mscFv + Dengue virus envelope protein<br />
+
**[[5aam]], [[5aaw]], [[7k93]] – mscFv + Dengue virus envelope protein<br />
**[[5kov]] – mscFv + Astrovirus envelope protein<br />
**[[5kov]] – mscFv + Astrovirus envelope protein<br />
 +
**[[6h3t]], [[6h3u]] – mscFv + bovine schmallenberg virus envelope protein<br />
 +
**[[6j11]] - mscFv + MERS-CoV spike protein<br />
**[[1dzb]], [[2znx]] – mscFv + lysozyme<br />
**[[1dzb]], [[2znx]] – mscFv + lysozyme<br />
**[[1a14]], [[1nmc]] – mscFv + neuraminidase<br />
**[[1a14]], [[1nmc]] – mscFv + neuraminidase<br />
**[[1fo0]], [[1kj2]], [[1nam]] – mscFv + TCR + MHC + peptide<br />
**[[1fo0]], [[1kj2]], [[1nam]] – mscFv + TCR + MHC + peptide<br />
-
**[[5d9q]] – hscFv + antibody + gp120 + gp40<br />
+
**[[6lgw]] – rmscFv + rabies glycoprotein<br />
-
 
+
* Single chain variable fragment complex with small molecule
* Single chain variable fragment complex with small molecule
Line 483: Line 641:
**[[4lar]] – hscFv + dexedrine<br />
**[[4lar]] – hscFv + dexedrine<br />
**[[4las]] – hscFv + amphetamine derivative<br />
**[[4las]] – hscFv + amphetamine derivative<br />
-
 
+
**[[6k4z]] – mscFv + NPA<br />
* Single chain variable fragment complex with peptide
* Single chain variable fragment complex with peptide
**[[5yax]] – hscFv + HBV peptide<br />
**[[5yax]] – hscFv + HBV peptide<br />
-
**[[5npi]], [[5npj]] – mscFv + hepatitis peptide<br />
 
**[[5a2i]], [[5aij]], [[5a2k]], [[5a2l]] – mscFv + TN peptide<br />
**[[5a2i]], [[5aij]], [[5a2k]], [[5a2l]] – mscFv + TN peptide<br />
**[[1p4b]] – mscFv + GCN4 peptide<br />
**[[1p4b]] – mscFv + GCN4 peptide<br />
-
**[[4h0h]], [[5fxc]], [[5owp]], [[1ktr]] – mscFv + peptide<br />
+
**[[4h0h]], [[5fxc]], [[5owp]], [[1ktr]], [[6fzq]], [[6tgg]] – mscFv + peptide<br />
-
*Single domain antibody VHH or Camelid antibody or nanobody NB80
+
*Single domain antibody VHH or Camelid antibody or nanobody
**[[5i0z]], [[5c6w]] – hVHH <br />
**[[5i0z]], [[5c6w]] – hVHH <br />
**[[6cnw]] – hyVHH - hybrid<br />
**[[6cnw]] – hyVHH - hybrid<br />
-
**[[4ppt]], [[4idl]], [[1shm]], [[2xa3]], [[5sv4]], [[4w81]], [[4w70]], [[4w68]], [[4tyu]], [[6ezw]], [[6f0d]], [[5nlu]], [[4krn]], [[4poy]], [[1sjv]], [[1u0q]], [[3qxu]], [[3qxw]], [[4b50]], [[5tp3]], [[1sjx]], [[4qgy]], [[5h8d]], [[4b5e]], [[6fys]] – LgVHH <br />
+
**[[4ppt]], [[4idl]], [[1shm]], [[2xa3]], [[5sv4]], [[4w81]], [[4w70]], [[4w68]], [[4tyu]], [[6ezw]], [[6f0d]], [[5nlu]], [[4krn]], [[4poy]], [[1sjv]], [[1u0q]], [[3qxu]], [[3qxw]], [[4b50]], [[5tp3]], [[1sjx]], [[4qgy]], [[5h8d]], [[4b5e]], [[6dbd]], [[6fpv]], [[6fys]], [[6oc8]], [[6ru3]], [[7lvu]] – LgVHH <br />
**[[1g9e]] – LgVHH - NMR<br />
**[[1g9e]] – LgVHH - NMR<br />
**[[4u05]] – LgVHH (mutant)<br />
**[[4u05]] – LgVHH (mutant)<br />
-
**[[4w2p]], [[6apo]], [[6apq]] – LgVHH anti-marburg virus<br />
+
**[[4w2p]], [[6apo]], [[6app]], [[6apq]] – LgVHH anti-marburg virus<br />
**[[6ck8]] – LgVHH anti-influenza virus<br />
**[[6ck8]] – LgVHH anti-influenza virus<br />
**[[3r0m]] – LgVHH anti-HIV<br />
**[[3r0m]] – LgVHH anti-HIV<br />
-
**[[2xxc]] – ViVHH anti-HIV - vicuna<br />
+
**[[2xxc]] – ViVHH anti-HIV - vicugna<br />
**[[6cwk]] – ViVHH anti-ricin<br />
**[[6cwk]] – ViVHH anti-ricin<br />
-
**[[5u64]], [[5u65]], [[1f2x]], [[1yc7]], [[5e7b]], [[5m7q]], [[5jmr]], [[3dwt]], [[3tpk]], [[3ln9]] – cVHH - camel<br />
+
**[[6dyx]], [[6iyn]] – ViVHH <br />
 +
**[[5u64]], [[5u65]], [[1f2x]], [[1yc7]], [[5e7b]], [[5m7q]], [[5jmr]], [[3dwt]], [[3tpk]], [[3ln9]], [[6heq]], [[6jb9]], [[6qtl]] – cVHH <br />
**[[1yc8]], [[3eak]] – cVHH (mutant)<br />
**[[1yc8]], [[3eak]] – cVHH (mutant)<br />
**[[6itp]], [[6itq]] – cVHH anti-cortisol<br />
**[[6itp]], [[6itq]] – cVHH anti-cortisol<br />
**[[6t2j]] – syVHH <br />
**[[6t2j]] – syVHH <br />
- 
*VHH binary complexes
*VHH binary complexes
**[[6oan]], [[6oao]] – hVHH + DBP<br />
**[[6oan]], [[6oao]] – hVHH + DBP<br />
 +
**[[6sge]] – hVHH + ROHB<br />
**[[1i3u]], [[1i3v]], [[1dq0]] - LgVHH + hapten<br />
**[[1i3u]], [[1i3v]], [[1dq0]] - LgVHH + hapten<br />
**[[3qxt]], [[3qxv]] – LgVHH + methotrexate<br />
**[[3qxt]], [[3qxv]] – LgVHH + methotrexate<br />
Line 527: Line 685:
**[[4hep]], [[4hem]] – LgVHH + BPP<br />
**[[4hep]], [[4hem]] – LgVHH + BPP<br />
**[[4w2q]], [[4w2o]], [[6app]] – LgVHH + Marburg virus nucleoprotein<br />
**[[4w2q]], [[4w2o]], [[6app]] – LgVHH + Marburg virus nucleoprotein<br />
-
**[[6fyt]], [[6fyu]], [[6fyw]] – LgVHH + Influenza virus hemagglutinin<br />
+
**[[6fyt]], [[6fyu]], [[6fyw]], [[6s0y]] – LgVHH + Influenza virus protein<br />
-
**[[6ana]], [[6and]], [[6ani]] – LgVHH + mouse antibody<br />
+
**[[6qx3]] – LgVHH + Influenza virus protein – Cryo EM<br />
 +
**[[6ana]], [[6and]], [[6ani]] – LgVHH + mFab<br />
**[[4krl]], [[4krm]] – LgVHH + EGFR<br />
**[[4krl]], [[4krm]] – LgVHH + EGFR<br />
**[[3rjq]] – LgVHH anti-HIV + gp120<br />
**[[3rjq]] – LgVHH anti-HIV + gp120<br />
**[[2bse]] – LgVHH + receptor-binding protein<br />
**[[2bse]] – LgVHH + receptor-binding protein<br />
**[[4ej1]], [[4eiz]], [[4eig]] – LgVHH + DHFR <br />
**[[4ej1]], [[4eiz]], [[4eig]] – LgVHH + DHFR <br />
-
**[[3p0g]], [[4lde]], [[4ldl]], [[4ldo]] – LgVHH + adrenergic receptor<br />
+
**[[3p0g]], [[4lde]], [[4ldl]], [[4ldo]], [[6mxt]], [[7bu7]] – LgVHH + adrenergic receptor<br />
**[[4n1h]], [[4m3k]], [[5lwf]] – LgVHH + beta-lactamase<br />
**[[4n1h]], [[4m3k]], [[5lwf]] – LgVHH + beta-lactamase<br />
**[[5m95]], [[5m94]], [[4wgw]], [[4wgv]] – LgVHH + metal cation transporter<br />
**[[5m95]], [[5m94]], [[4wgw]], [[4wgv]] – LgVHH + metal cation transporter<br />
-
**[[5h8o]] – LgVHH + ASC<br />
+
**[[5h8o]], [[6f2g]] – LgVHH + ASC<br />
**[[3k3q]] – LgVHH + Botox<br />
**[[3k3q]] – LgVHH + Botox<br />
**[[4wem]], [[4wen]], [[4weu]] – LgVHH + adhesin<br />
**[[4wem]], [[4wen]], [[4weu]] – LgVHH + adhesin<br />
**[[4p2c]] – LgVHH + Shiga toxin<br />
**[[4p2c]] – LgVHH + Shiga toxin<br />
 +
**[[6oq5]], [[6oq6]], [[6oq7]], [[6oq8]] – LgVHH + Clostridium toxin<br />
 +
**[[6hjx]], [[6ssi]] – LgVHH + ELIC<br />
**[[4aq1]] – LgVHH + SBSB<br />
**[[4aq1]] – LgVHH + SBSB<br />
**[[6h7j]], [[6h7l]], [[6h7m]], [[6h7n]] – lgVHH + thioredoxin + adrenergic receptor <br />
**[[6h7j]], [[6h7l]], [[6h7m]], [[6h7n]] – lgVHH + thioredoxin + adrenergic receptor <br />
-
**[[1jto]], [[1jtp]], [[1jtt]], [[1ri8]], [[1xfp]], [[1zmy]], [[1zv5]], [[1zvh]], [[4i0c]], [[1op9]], [[1mel]], [[1rjc]], [[1zvy]] – cVHH + lysozyme<br />
+
**[[6u51]], [[6u52]], [[6u54]], [[6u55]] – LgVHH anti-ebola + nucleoprotein<br />
-
**[[2x89]] – cVHH + β-2-microglobulin<br />
+
**[[7lvw]] – LgVHH + RSV fusion protein<br />
-
**[[1kxq]], [[1kxt]], [[1kxv]] – cVHH + α-amylase<br />
+
**[[6war]] - LgVHH + MERS-CoV spike protein<br />
-
**[[3qsk]], [[2p42]], [[2p43]], [[2p44]], [[2p45]], [[2p46]], [[2p47]], [[2p48]], [[2p49]], [[2p4a]] – cVHH + RNAse 1<br />
+
**[[6qup]] – LgVHH + receptor kinase<br />
 +
**[[6qgy]] – LgVHH + BamA<br />
 +
**[[6rvc]] – LgVHH + PTCH1<br />
 +
**[[6z6v]] – LgVHH + complement C1<br />
 +
**[[6h15]] – LgVHH + LRP6<br />
 +
**[[6b73]] – LgVHH + opioid receptor<br />
 +
**[[6i8g]] – LgVHH + EDS1<br />
 +
**[[6hhu]] – LgVHH + SAP<br />
 +
**[[6c9w]] – LgVHH + lactose permease<br />
 +
**[[6h02]] – LgVHH + mediator of RNA polymerase<br />
 +
**[[6gs4]] – LgVHH + DtpA<br />
 +
**[[6z1v]] – LgVHH + CD9<br />
 +
**[[6f5g]] - LgVHH + PCSK9 <br />
**[[4tvs]] – viVHH + LAP1<br />
**[[4tvs]] – viVHH + LAP1<br />
**[[4yga]] – ViVHH + CDPK1<br />
**[[4yga]] – ViVHH + CDPK1<br />
**[[5l21]] – ViVHH + Botox<br />
**[[5l21]] – ViVHH + Botox<br />
**[[2xt1]], [[2xxm]] – ViVHH anti-HIV + HIV capsid<br />
**[[2xt1]], [[2xxm]] – ViVHH anti-HIV + HIV capsid<br />
-
**[[5o04]], [[5o02]], [[5o03]], [[5o05]], [[5tjw]], [[5omn]], [[4x7c]], [[4x7d]], [[4x7e]], [[4x7f]], [[5m30]] – ViVHH + virus capsid<br />
+
**[[5o04]], [[5o02]], [[5o03]], [[5o05]], [[5tjw]], [[5omn]], [[4x7c]], [[4x7d]], [[4x7e]], [[4x7f]], [[5m30]], [[6h6y]], [[6h71]], [[6h72]], [[6xw4]], [[6xw5]], [[6xw6]] – ViVHH + virus capsid<br />
**[[2xv6]] – ViVHH + p24<br />
**[[2xv6]] – ViVHH + p24<br />
**[[5hvf]], [[5hvg]], [[5hvh]] – ViVHH + carboxypeptidase<br />
**[[5hvf]], [[5hvg]], [[5hvh]] – ViVHH + carboxypeptidase<br />
**[[5hgg]], [[5lhr]], [[5lhq]], [[5lhp]], [[5lhn]] – ViVHH + urokinase-type plasminogen activator <br />
**[[5hgg]], [[5lhr]], [[5lhq]], [[5lhp]], [[5lhn]] – ViVHH + urokinase-type plasminogen activator <br />
 +
**[[6gwn]], [[6gwp]], [[7aqg]] – ViVHH + plasminogen activator inhibitor<br />
**[[5vxm]], [[5vxj]], [[5vxk]], [[5vxl]], [[5vlj]] - ViVHH + invasion IpaD<br />
**[[5vxm]], [[5vxj]], [[5vxk]], [[5vxl]], [[5vlj]] - ViVHH + invasion IpaD<br />
**[[5u4l]], [[4z9k]], [[4lhj]], [[4lgp]], [[6cwg]], [[5u4m]], [[6obc]], [[6obe]], [[6obg]], [[6obm]], [[6obo]], [[6oca]], [[6ocd]] – ViVHH anti-ricin + ricin<br />
**[[5u4l]], [[4z9k]], [[4lhj]], [[4lgp]], [[6cwg]], [[5u4m]], [[6obc]], [[6obe]], [[6obg]], [[6obm]], [[6obo]], [[6oca]], [[6ocd]] – ViVHH anti-ricin + ricin<br />
 +
**[[6x06]], [[6x07]], [[6x08]] – ViVHH + nucleoporin<br />
 +
**[[6rah]], [[6rai]] – ViVHH + TmrAB<br />
 +
**[[1jto]], [[1jtp]], [[1jtt]], [[1ri8]], [[1xfp]], [[1zmy]], [[1zv5]], [[1zvh]], [[4i0c]], [[1op9]], [[1mel]], [[1rjc]], [[1zvy]], [[6jb8]] – cVHH + lysozyme<br />
 +
**[[6jb2]], [[6jb5]] – cVHH (mutant) + lysozyme<br />
 +
**[[2x89]] – cVHH + β-2-microglobulin<br />
 +
**[[1kxq]], [[1kxt]], [[1kxv]] – cVHH + α-amylase<br />
 +
**[[3qsk]], [[2p42]], [[2p43]], [[2p44]], [[2p45]], [[2p46]], [[2p47]], [[2p48]], [[2p49]], [[2p4a]] – cVHH + RNAse 1<br />
 +
**[[6ir1]], [[6ir2]] – cVHH + mCherry<br />
 +
**[[6lr7]] – cVHH + GFP<br />
 +
**[[6rpj]] – cVHH + CTLA<br />
 +
**[[6hhd]] – cVHH + major prion protein<br />
**[[6knm]] - cVHH + apelin receptor<br />
**[[6knm]] - cVHH + apelin receptor<br />
-
**[[6sc5]], [[6sc6]], [[6sc7]], [[6sc8]], [[6sc9]] – syVHH + RNF31<br />
+
**[[6sc5]], [[6sc6]], [[6sc7]], [[6sc8]], [[6sc9]] – syVHH + RNF31<br/>
-
 
+
*VHH ternary complexes
*VHH ternary complexes
Line 564: Line 748:
**[[3v0a]] – LgVHH + BONT/A1 + NTNH<br />
**[[3v0a]] – LgVHH + BONT/A1 + NTNH<br />
**[[3sn6]] – LgVHH + adrenergic receptor + guanine nucleotide-binding protein<br />
**[[3sn6]] – LgVHH + adrenergic receptor + guanine nucleotide-binding protein<br />
 +
**[[7bts]], [[7bu6]] – LgVHH + adrenergic receptor + epinephrine<br />
**[[6oya]] - LgVHH + guanine nucleotide-binding protein + transducin + rhodopsin + GT-alpha/GI1-alpha – Cryo EM<br />
**[[6oya]] - LgVHH + guanine nucleotide-binding protein + transducin + rhodopsin + GT-alpha/GI1-alpha – Cryo EM<br />
**[[4laj]] - LgVHH + envelope glycoprotein gp120 + CD4<br />
**[[4laj]] - LgVHH + envelope glycoprotein gp120 + CD4<br />
**[[4orz]] – LgVHH + tyrosine protein kinase HCK + NEF<br />
**[[4orz]] – LgVHH + tyrosine protein kinase HCK + NEF<br />
 +
**[[6v7z]] – LgVHH + CD1d + b-2-microglobulin<br />
 +
**[[6v80]] – LgVHH + CD1d + NKT TCR + b-2-microglobulin<br />
**[[4kro]], [[4krp]] – LgVHH + antibody + EGFR<br />
**[[4kro]], [[4krp]] – LgVHH + antibody + EGFR<br />
**[[5j1s]], [[5j1t]] – ViVHH + Torsin + LULL1<br />
**[[5j1s]], [[5j1t]] – ViVHH + Torsin + LULL1<br />
**[[5uk4]], [[5ukb]] – ViVHH + virus capsid + RNA<br />
**[[5uk4]], [[5ukb]] – ViVHH + virus capsid + RNA<br />
**[[5jmo]] – cVHH + furin + CMK inhibitor<br />
**[[5jmo]] – cVHH + furin + CMK inhibitor<br />
-
**[[5fuc]] – cVHH + IL-6 + IL-6 receptor<br />
+
**[[5fuc]] – cVHH + IL-6 + IL-6R <br />
-
**[[6h7o]], [[6ibl]] – cVHH + thioredoxin + adrenergic receptor<br />
+
**[[6h7j]], [[6h7l]], [[6h7m]], [[6h7o]], [[6ibl]] – cVHH + thioredoxin + adrenergic receptor<br />
 +
**[[6n48]] – cVHH + modulator + adrenergic receptor<br />
 +
**[[6do1]] – syVHH + BRIL + S1I8 peptide<br/>
 +
 
 +
*Intrabody or anti-helix antibody
 +
 
 +
**[[6k67]] – hIB 3LRH + calmodulin<br />
 +
**[[6k3m]], [[6k64]], [[6k6a]], [[6k6b]] – hIB 3LRH + SpA IgG-binding domain protein<br />
 +
**[[6k69]] – hIB 3LRH + T4 lysozyme<br />
 +
 
}}
}}
[[Category: Topic Page]]
[[Category: Topic Page]]

Revision as of 09:01, 4 April 2021

Humanized mouse antibody (hmFab) is a modified mFab which resembles more hFab.
Broadly neutralizing Fab and Neutralizing Fab are anti-HIV Fab.
Lama antibodies or nanobodies or camelid or VHH are natural single-domain antibodies containing just the heavy chain.
scFv is a single chain variable fragment in a fusion protein of the variable regions of the heavy and light chains of immunoglobulin.

3D structures of Antibody

Updated on 04-April-2021


Proteopedia Page Contributors and Editors (what is this?)

Joel L. Sussman, Michal Harel, Jaime Prilusky

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