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Gp120 3D structures
From Proteopedia
(Difference between revisions)
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{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | *Gp120 from HIV-1; Domains – Clade A/E 1-140; outer – 1-181; RHPA 1-216; V1-V2 118-246; V3 296-331; core | + | *Gp120 from HIV-1; Domains – Clade A/E 1-140; outer – 1-181; RHPA 1-216; V1-V2 118-246; V3 296-331; core 1-353; C5 484-506 |
| - | **[[3dnl]], [[3dnn]], [[3dno]], [[3tgq]], [[3tgr]], [[3tgt]], [[3tih]], [[5f4u]] - Gp120 core<br /> | + | **[[3dnl]], [[3dnn]], [[3dno]], [[3tgq]], [[3tgr]], [[3tgt]], [[3tih]], [[5f4u]], [[6utb]], [[6utd]] - Gp120 core<br /> |
**[[5fa2]] - Gp120 core (mutant)<br /> | **[[5fa2]] - Gp120 core (mutant)<br /> | ||
**[[1meq]] – GP120 C5 domain – NMR<br /> | **[[1meq]] – GP120 C5 domain – NMR<br /> | ||
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**[[5t33]] - Gp120 RHPA + antibody <br /> | **[[5t33]] - Gp120 RHPA + antibody <br /> | ||
**[[3u2s]] - Gp120 V1V2 region + antibody PG9<br /> | **[[3u2s]] - Gp120 V1V2 region + antibody PG9<br /> | ||
| - | **[[3se8]], [[3se9]], [[3hi1]], [[3rjq]], [[4jkp]], [[4jm2]], [[4lss]], [[4lsv]], [[4ywg]], [[4xvs]], [[3ngb]], [[4ye4]], [[4rwy]], [[4jan]], [[4lst]], [[5te7]], [[5f6j]], [[5te4]], [[6bf4]], [[5wb9]], [[5w6d]], [[5ukr]], [[5uem]], [[5igx]], [[4dvr]] - Gp120 + antibody<br /> | + | **[[3se8]], [[3se9]], [[3hi1]], [[3rjq]], [[4jkp]], [[4jm2]], [[4lss]], [[4lsv]], [[4ywg]], [[4xvs]], [[3ngb]], [[4ye4]], [[4rwy]], [[4jan]], [[4lst]], [[5te7]], [[5f6j]], [[5te4]], [[6bf4]], [[5wb9]], [[5w6d]], [[5ukr]], [[5uem]], [[5igx]], [[4dvr]] - Gp120 core + antibody<br /> |
| - | **[[3idx]], [[3idy]], [[2ny7]], [[4jdt]], [[5fyl]], [[5fec]], [[6bck]], [[6p8m]] - Gp120 core (mutant) + antibody <br /> | + | **[[3idx]], [[3idy]], [[2ny7]], [[4jdt]], [[5fyl]], [[5fec]], [[6bck]], [[6p8m]], [[6oz2]], [[6oz3]] - Gp120 core (mutant) + antibody <br /> |
| - | **[[6v0r]], [[6vfl]], [[6vrw]] - Gp120 | + | **[[6p8m]], [[6xcj]] - Gp120 44-494 + antibody <br /> |
| + | **[[6v0r]], [[6vfl]], [[6vrw]], [[7l7t]], [[7l7u]] - Gp120 33-513 + Gp41 – Cryo EM <br /> | ||
**[[6l1y]] - Gp120 core + CD4 <br /> | **[[6l1y]] - Gp120 core + CD4 <br /> | ||
**[[4rz8]], [[5f4l]], [[5f4p]], [[5f4r]] - Gp120 core + CD4 mimic <br /> | **[[4rz8]], [[5f4l]], [[5f4p]], [[5f4r]] - Gp120 core + CD4 mimic <br /> | ||
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**[[4jzw]], [[4jzz]], [[4k0a]], [[4ka2]] - Gp120 core + CD4 mimetic miniprotein<br /> | **[[4jzw]], [[4jzz]], [[4k0a]], [[4ka2]] - Gp120 core + CD4 mimetic miniprotein<br /> | ||
**[[4jpj]], [[4rx4]] - Gp120 Clade A + antibody <br /> | **[[4jpj]], [[4rx4]] - Gp120 Clade A + antibody <br /> | ||
| + | **[[7klc]] - Gp120 Clade A 43-126,194-489 + antibody <br /> | ||
| + | **[[7jks]], [[7jkt]] - Gp120 43-510 + antibody <br /> | ||
**[[6one]], [[6onf]], [[6onh]], [[6onv]], [[6ooo]], [[6p9n]] - Gp120 Clade A/E (mutant) + CD4 mimetic<br /> | **[[6one]], [[6onf]], [[6onh]], [[6onv]], [[6ooo]], [[6p9n]] - Gp120 Clade A/E (mutant) + CD4 mimetic<br /> | ||
| - | **[[3tgs]], [[4dko]], [[4dkp]], [[4dkq]], [[4dkr]] - Gp120 core + piperidine derivative<br /> | + | **[[3tgs]], [[4dko]], [[4dkp]], [[4dkq]], [[4dkr]], [[6ooo]] - Gp120 core + piperidine derivative<br /> |
**[[5u6e]] - Gp120 core + pyrrole derivative<br /> | **[[5u6e]] - Gp120 core + pyrrole derivative<br /> | ||
| - | **[[4dvx]], [[4dvw]], [[4dvv]], [[4dvt]], [[4dvs]] - Gp120 core (mutant) + piperazine derivative<br /> | + | **[[4dvx]], [[4dvw]], [[4dvv]], [[4dvt]], [[4dvs]], [[6uw]] - Gp120 core (mutant) + piperazine derivative<br /> |
| + | **[[6ut1]] - Gp120 core (mutant) + inhibitor<br /> | ||
*Gp120 ternary complex | *Gp120 ternary complex | ||
| - | **[[5kjr]] - Gp120 Clade A/E + M48U1 peptide + antibody<br /> | + | **[[5kjr]], [[6mfp]] - Gp120 Clade A/E + M48U1 peptide + antibody<br /> |
| - | **[[4rfo]], [[4rfn]] - Gp120 Clade A/E (mutant) + M48U1 peptide + antibody<br /> | + | **[[4rfo]], [[4rfn]], [[6mg7]] - Gp120 Clade A/E 4-492 (mutant) + M48U1 peptide + antibody<br /> |
**[[4h8w]] - Gp120 Clade A/E + CD4 + antibody<br /> | **[[4h8w]] - Gp120 Clade A/E + CD4 + antibody<br /> | ||
**[[3jwd]], [[3jwo]], [[2i5y]], [[2i60]] - Gp120 core + hCD4 N terminal + antibody <br /> | **[[3jwd]], [[3jwo]], [[2i5y]], [[2i60]] - Gp120 core + hCD4 N terminal + antibody <br /> | ||
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**[[5a8h]], [[5a7x]], [[4rqs]], [[4r4h]], [[4r2g]], [[4p9h]] - Gp120 core + hCD4 D1-D2 domain + antibody<br /> | **[[5a8h]], [[5a7x]], [[4rqs]], [[4r4h]], [[4r2g]], [[4p9h]] - Gp120 core + hCD4 D1-D2 domain + antibody<br /> | ||
**[[4laj]] - Gp120 core + CD4 mimetic miniprotein + antibody<br /> | **[[4laj]] - Gp120 core + CD4 mimetic miniprotein + antibody<br /> | ||
| - | **[[5w4l]], [[6w4m]] - Gp120 core (mutant) + CD4 mimetic peptide + antibody<br /> | + | **[[5w4l]], [[6w4m]], [[6w4m]] - Gp120 core (mutant) + CD4 mimetic peptide + antibody<br /> |
**[[4r4f]], [[4r4n]] - Gp120 core + M48U1 peptide + antibody<br /> | **[[4r4f]], [[4r4n]] - Gp120 core + M48U1 peptide + antibody<br /> | ||
| - | **[[5v8l]], [[5v8m]], [[5uty]], [[5utf]], [[5um8]], [[5jsa]], [[5js9]], [[5i8h]], [[5d9q]], [[5cjx]], [[5c7k | + | **[[5v8l]], [[5v8m]], [[5uty]], [[5utf]], [[5um8]], [[5jsa]], [[5js9]], [[5i8h]], [[5d9q]], [[5cjx]], [[5c7k]], [[6mft]], [[6mdt]], [[6mco]], [[6d2p]], [[6ck9]], [[6ch9]], [[6ch8]], [[6ch7]] - Gp120 core + Gp41 + antibody<br /> |
| + | **[[6ccb]], [[6x5b]], [[6x9r]], [[6x9s]], [[6x9t]], [[6x9u]], [[6x9v]] - Gp120 29-504 (mutant) + Gp41 + antibody<br /> | ||
**[[5fyk]], [[5fyj]], [[4nco]], [[6nnj]], [[6nnf]], [[6nm6]] - Gp120 core (mutant) + Gp41 + antibody<br /> | **[[5fyk]], [[5fyj]], [[4nco]], [[6nnj]], [[6nnf]], [[6nm6]] - Gp120 core (mutant) + Gp41 + antibody<br /> | ||
| - | **[[6cde]], [[6cdi]], [[ | + | **[[6cde]], [[6cdi]], [[6okp]], [[6e5p]], [[6cuf]], [[6cue]], [[6chb]], [[5u1f]], [[5thr]], [[4cc8]], [[3j70]], [[6u59]], [[6uda]], [[6udk]], [[6v8z]], [[6vlr]], [[6vo1]], [[6vtt]], [[7lo6]] - Gp120 core + Gp41 + antibody – Cryo EM<br /> |
| + | **[[6mn7]], [[6nqd]], [[6olp]], [[6orn]], [[6oro]], [[6orp]], [[6orq]], [[6pw6]], [[6u59]], [[6uda]], [[6ulc]], [[6um6]], [[6um7]], [[6v8x]], [[6vi0]], [[6vo0]], [[6vo3]], [[6vtt]], [[6vy2]], [[7l86]], [[7l87]], [[7l88]], [[7l89]], [[7l8a]], [[7l8b]], [[7l8c]], [[7l8d]], [[7l8s]], [[7l8t]], [[7l8u]], [[7l8w]], [[7l8x]], [[7l8y]], [[7l8z]], [[7l90]], [[7ll1]], [[7ll2]], [[7llk]], [[7lua]] - Gp120 29-508 + Gp41 + antibody – Cryo EM<br /> | ||
| + | **[[6nc2]], [[6nc3]] - Gp120 29-508 (mutant) + Gp41 + antibody – Cryo EM<br /> | ||
**[[3j5m]] - Gp120 core (mutant) + Gp41 + antibody – Cryo EM<br /> | **[[3j5m]] - Gp120 core (mutant) + Gp41 + antibody – Cryo EM<br /> | ||
| - | **[[6u0n]] - Gp120 | + | **[[6u0n]] - Gp120 32-505 + Gp41 + antibody + CD4 – Cryo EM<br /> |
| - | **[[6um5]] - Gp120 | + | **[[6um5]] - Gp120 30-489 + Gp41 + antibody + CH848 – Cryo EM<br /> |
| - | **[[6vpx]] - Gp120 core + Gp41 + antibody + peptide – Cryo EM<br /> | + | **[[6vpx]], [[7lok]] - Gp120 core + Gp41 + antibody + peptide – Cryo EM<br /> |
*Gp120 from HIV-2 binary complex | *Gp120 from HIV-2 binary complex | ||
Revision as of 09:46, 15 August 2021
3D structures of Gp120
Updated on 15-August-2021
