1ccn

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[[Image:1ccn.jpg|left|200px]]
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{{Seed}}
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[[Image:1ccn.png|left|200px]]
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{{STRUCTURE_1ccn| PDB=1ccn | SCENE= }}
{{STRUCTURE_1ccn| PDB=1ccn | SCENE= }}
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'''DIRECT NOE REFINEMENT OF CRAMBIN FROM 2D NMR DATA USING A SLOW-COOLING ANNEALING PROTOCOL'''
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===DIRECT NOE REFINEMENT OF CRAMBIN FROM 2D NMR DATA USING A SLOW-COOLING ANNEALING PROTOCOL===
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==Overview==
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A set of computer programs called DINOSAUR has been developed, which allows the refinement of biomolecular structures directly from 2D NOE intensities. The NOE restraining potential implemented emphasises the weak intensities corresponding to larger distances which are more likely to determine the three-dimensional structure. An approximation based on a two-spin approximation is proposed for the gradient of the NOE intensities instead of the exact solution which is extremely time-consuming. The DINOSAUR routines have been implemented in various refinement programs (Distance bound Driven Dynamics, Molecular Dynamics and Energy Minimisation) and tested on an eight-residue model peptide.
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(as it appears on PubMed at http://www.pubmed.gov), where 1841701 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1841701}}
==About this Structure==
==About this Structure==
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1CCN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Crambe_hispanica_subsp._abyssinica Crambe hispanica subsp. abyssinica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CCN OCA].
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1CCN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Crambe_hispanica_subsp._abyssinica Crambe hispanica subsp. abyssinica]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CCN OCA].
==Reference==
==Reference==
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[[Category: Rullmann, J A.C.]]
[[Category: Rullmann, J A.C.]]
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[[Category: Plant seed protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 12:35:16 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 20:33:42 2008''

Revision as of 17:33, 30 June 2008

Template:STRUCTURE 1ccn

DIRECT NOE REFINEMENT OF CRAMBIN FROM 2D NMR DATA USING A SLOW-COOLING ANNEALING PROTOCOL

Template:ABSTRACT PUBMED 1841701

About this Structure

1CCN is a Single protein structure of sequence from Crambe hispanica subsp. abyssinica. Full experimental information is available from OCA.

Reference

Direct NOE refinement of biomolecular structures using 2D NMR data., Bonvin AM, Boelens R, Kaptein R, J Biomol NMR. 1991 Sep;1(3):305-9. PMID:1841701

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