This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7cbn
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of beta-N-acetylhexosaminidase Am0868 from Akkermansia muciniphila== | ==Crystal structure of beta-N-acetylhexosaminidase Am0868 from Akkermansia muciniphila== | ||
| - | <StructureSection load='7cbn' size='340' side='right'caption='[[7cbn]]' scene=''> | + | <StructureSection load='7cbn' size='340' side='right'caption='[[7cbn]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CBN OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[7cbn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Akkermansia_muciniphila_ATCC_BAA-835 Akkermansia muciniphila ATCC BAA-835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CBN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CBN FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cbn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cbn OCA], [https://pdbe.org/7cbn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cbn RCSB], [https://www.ebi.ac.uk/pdbsum/7cbn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cbn ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/H0868_AKKM8 H0868_AKKM8] Potentially capable of cleaving the specific glycoside linkages in the process of mucin degradation in human intestinal tract (Probable). Hydrolyzes chromogenic substrates pNP-beta-GlcNAc with high activity and pNP-beta-GalNAc to a lesser extent, but not pNP-beta-glucose or pNP-beta-galactose (PubMed:32819592).<ref>PMID:32819592</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Beta-N-acetylhexosaminidase 3D structures|Beta-N-acetylhexosaminidase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Akkermansia muciniphila ATCC BAA-835]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Wang M]] | [[Category: Wang M]] | ||
[[Category: Xu W]] | [[Category: Xu W]] | ||
[[Category: Zhang M]] | [[Category: Zhang M]] | ||
Current revision
Crystal structure of beta-N-acetylhexosaminidase Am0868 from Akkermansia muciniphila
| |||||||||||
