7jh3

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==Crystal structure of 4-aminobutyrate aminotransferase PuuE from Escherichia coli in complex with PLP==
==Crystal structure of 4-aminobutyrate aminotransferase PuuE from Escherichia coli in complex with PLP==
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<StructureSection load='7jh3' size='340' side='right'caption='[[7jh3]]' scene=''>
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<StructureSection load='7jh3' size='340' side='right'caption='[[7jh3]], [[Resolution|resolution]] 2.68&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JH3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7JH3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7jh3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JH3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JH3 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7jh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jh3 OCA], [http://pdbe.org/7jh3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7jh3 RCSB], [http://www.ebi.ac.uk/pdbsum/7jh3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7jh3 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.68&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jh3 OCA], [https://pdbe.org/7jh3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jh3 RCSB], [https://www.ebi.ac.uk/pdbsum/7jh3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jh3 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PUUE_ECOLI PUUE_ECOLI] Catalyzes the transfer of the amino group from gamma-aminobutyrate (GABA) to alpha-ketoglutarate (KG) to yield succinic semialdehyde (SSA). PuuE is important for utilization of putrescine as the sole nitrogen or carbon source.<ref>PMID:15590624</ref> <ref>PMID:20639325</ref>
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==See Also==
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*[[Aminotransferase 3D structures|Aminotransferase 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Di Leo R]]
[[Category: Di Leo R]]

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Crystal structure of 4-aminobutyrate aminotransferase PuuE from Escherichia coli in complex with PLP

PDB ID 7jh3

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