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6ov6

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Current revision (14:53, 13 March 2024) (edit) (undo)
 
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<StructureSection load='6ov6' size='340' side='right'caption='[[6ov6]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
<StructureSection load='6ov6' size='340' side='right'caption='[[6ov6]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6ov6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bizionia_argentinensis_jub59 Bizionia argentinensis jub59]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OV6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6OV6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6ov6]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bizionia_argentinensis_JUB59 Bizionia argentinensis JUB59]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OV6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OV6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BZARG_797 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1046627 Bizionia argentinensis JUB59])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ov6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ov6 OCA], [http://pdbe.org/6ov6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ov6 RCSB], [http://www.ebi.ac.uk/pdbsum/6ov6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ov6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ov6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ov6 OCA], [https://pdbe.org/6ov6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ov6 RCSB], [https://www.ebi.ac.uk/pdbsum/6ov6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ov6 ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/G2EBB4_9FLAO G2EBB4_9FLAO]
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Tailed bacteriophages are one of the most widespread biological entities on Earth. Their singular structures, such as spikes or fibers are of special interest given their potential use in a wide range of biotechnological applications. In particular, the long fibers present at the termini of the T4 phage tail have been studied in detail and are important for host recognition and adsorption. Although significant progress has been made in elucidating structural mechanisms of model phages, the high-resolution structural description of the vast population of marine phages is still unexplored. In this context, we present here the crystal structure of C24, a putative receptor-binding tip-like protein from Bizionia argentinensis JUB59, a psychrotolerant bacterium isolated from the marine surface waters of Potter Cove, Antarctica. The structure resembles the receptor-binding tip from the bacteriophage T4 long tail fiber yet showing marked differences in its domain organization, size, sequence identity and metal binding nature. We confirmed the viral origin of C24 by induction experiments using mitomycin C. Our results reveal the presence of a novel uncharacterized prophage in the genome of B. argentinensis JUB59, whose morphology is compatible with the order Caudovirales and that carries the nucleotide sequence of C24 in its genome. This work provides valuable information to expand our current knowledge on the viral machinery prevalent in the oceans.
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Structure of the putative long tail fiber receptor-binding tip of a novel temperate bacteriophage from the Antarctic bacterium Bizionia argentinensis JUB59.,Pellizza L, Lopez JL, Vazquez S, Sycz G, Guimaraes BG, Rinaldi J, Goldbaum FA, Aran M, Mac Cormack WP, Klinke S J Struct Biol. 2020 Jul 28:107595. doi: 10.1016/j.jsb.2020.107595. PMID:32736071<ref>PMID:32736071</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 6ov6" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bizionia argentinensis jub59]]
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[[Category: Bizionia argentinensis JUB59]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Aran, M]]
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[[Category: Aran M]]
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[[Category: Guimaraes, B G]]
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[[Category: Guimaraes BG]]
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[[Category: Klinke, S]]
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[[Category: Klinke S]]
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[[Category: Pellizza, L]]
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[[Category: Pellizza L]]
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[[Category: Rinaldi, J]]
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[[Category: Rinaldi J]]
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[[Category: Fiber]]
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[[Category: Unknown function]]
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[[Category: Viral origin]]
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Current revision

CRYSTALLOGRAPHIC STRUCTURE OF THE C24 PROTEIN FROM THE ANTARCTIC MICROORGANISM BIZIONIA ARGENTINENSIS

PDB ID 6ov6

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