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5llj

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Current revision (18:33, 18 October 2023) (edit) (undo)
 
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<StructureSection load='5llj' size='340' side='right'caption='[[5llj]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
<StructureSection load='5llj' size='340' side='right'caption='[[5llj]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5llj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mvv Mvv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LLJ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5LLJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5llj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Visna/maedi_virus_EV1_KV1772 Visna/maedi virus EV1 KV1772]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LLJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36374 MVV])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5llj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5llj OCA], [http://pdbe.org/5llj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5llj RCSB], [http://www.ebi.ac.uk/pdbsum/5llj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5llj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5llj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5llj OCA], [https://pdbe.org/5llj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5llj RCSB], [https://www.ebi.ac.uk/pdbsum/5llj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5llj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/POL_VILVK POL_VILVK]] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.
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[https://www.uniprot.org/uniprot/POL_VILVK POL_VILVK] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Mvv]]
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[[Category: Visna/maedi virus EV1 KV1772]]
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[[Category: Cherepanov, P]]
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[[Category: Cherepanov P]]
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[[Category: Maskell, D P]]
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[[Category: Maskell DP]]
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[[Category: Pye, V E]]
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[[Category: Pye VE]]
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[[Category: C-terminal domain]]
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[[Category: Integrase]]
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[[Category: Viral protein]]
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[[Category: Visna/maedi virus]]
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Current revision

Maedi-Visna virus (MVV) integrase C-terminal domain (residues 220-276)

PDB ID 5llj

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