5lzk
From Proteopedia
(Difference between revisions)
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<StructureSection load='5lzk' size='340' side='right'caption='[[5lzk]], [[Resolution|resolution]] 1.57Å' scene=''> | <StructureSection load='5lzk' size='340' side='right'caption='[[5lzk]], [[Resolution|resolution]] 1.57Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5lzk]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5lzk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LZK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LZK FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.575Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lzk OCA], [https://pdbe.org/5lzk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lzk RCSB], [https://www.ebi.ac.uk/pdbsum/5lzk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lzk ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/FA83B_HUMAN FA83B_HUMAN] Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.<ref>PMID:22886302</ref> <ref>PMID:23676467</ref> <ref>PMID:23912460</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bountra | + | [[Category: Bountra C]] |
| - | [[Category: Bufton | + | [[Category: Bufton JC]] |
| - | [[Category: Bullock | + | [[Category: Bullock A]] |
| - | [[Category: Burgess-Brown | + | [[Category: Burgess-Brown NA]] |
| - | + | [[Category: Edwards AM]] | |
| - | [[Category: Edwards | + | [[Category: Pinkas DM]] |
| - | [[Category: Pinkas | + | [[Category: Shrestha L]] |
| - | + | [[Category: Williams EP]] | |
| - | [[Category: Shrestha | + | [[Category: Von Delft F]] |
| - | [[Category: Williams | + | |
| - | [[Category: | + | |
| - | + | ||
Current revision
Structure of the domain of unknown function DUF1669 from human FAM83B
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